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Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

Deep learning has shown remarkable performance in medical image segmentation. However, despite its promise, deep learning has many challenges in practice due to its inability to effectively transition to unseen domains, caused by the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Dewei Hu , Hao Li , Han Liu , Jiacheng Wang , Xing Yao , Daiwei Lu , Ipek Oguz

Imputation of missing images via source-to-target modality translation can improve diversity in medical imaging protocols. A pervasive approach for synthesizing target images involves one-shot mapping through generative adversarial networks…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Muzaffer Özbey , Onat Dalmaz , Salman UH Dar , Hasan A Bedel , Şaban Özturk , Alper Güngör , Tolga Çukur

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

Neurons and Cognition · Quantitative Biology 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Accurate diagnosis of Alzheimer's disease (AD) is essential for enabling timely intervention and slowing disease progression. Multimodal diagnostic approaches offer considerable promise by integrating complementary information across…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Yujie Nie , Jianzhang Ni , Yonglong Ye , Yuan-Ting Zhang , Yun Kwok Wing , Xiangqing Xu , Xin Ma , Lizhou Fan

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang

With the advancement of AIGC, video frame interpolation (VFI) has become a crucial component in existing video generation frameworks, attracting widespread research interest. For the VFI task, the motion estimation between neighboring…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Zhilin Huang , Yijie Yu , Ling Yang , Chujun Qin , Bing Zheng , Xiawu Zheng , Zikun Zhou , Yaowei Wang , Wenming Yang

Characterizing a preclinical stage of Alzheimer's Disease (AD) via single imaging is difficult as its early symptoms are quite subtle. Therefore, many neuroimaging studies are curated with various imaging modalities, e.g., MRI and PET,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Seunghun Baek , Jaeyoon Sim , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Multimodal Image Fusion (MMIF) aims to integrate complementary information from different imaging modalities to overcome the limitations of individual sensors. It enhances image quality and facilitates downstream applications such as remote…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Mengyu Wang , Zhenyu Liu , Kun Li , Yu Wang , Yuwei Wang , Yanyan Wei , Fei Wang

Medical data collected for diagnostic decisions are typically multimodal, providing comprehensive information on a subject. While computer-aided diagnosis systems can benefit from multimodal inputs, effectively fusing such data remains a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Qiuhui Chen , Yi Hong

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Anomaly synthesis is one of the effective methods to augment abnormal samples for training. However, current anomaly synthesis methods predominantly rely on texture information as input, which limits the fidelity of synthesized abnormal…

Computer Vision and Pattern Recognition · Computer Science 2024-05-03 Jie Hu , Yawen Huang , Yilin Lu , Guoyang Xie , Guannan Jiang , Yefeng Zheng , Zhichao Lu

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Accurate brain tumor segmentation is essential for preoperative evaluation and personalized treatment. Multi-modal MRI is widely used due to its ability to capture complementary tumor features across different sequences. However, in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Shenghao Zhu , Yifei Chen , Weihong Chen , Shuo Jiang , Guanyu Zhou , Yuanhan Wang , Feiwei Qin , Changmiao Wang , Qiyuan Tian

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Bhavesh Sandbhor , Bheeshm Sharma , Balamurugan Palaniappan

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou