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Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Federated learning (FL) effectively mitigates the data silo challenge brought about by policies and privacy concerns, implicitly harnessing more data for deep model training. However, traditional centralized FL models grapple with diverse…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Li Lin , Yixiang Liu , Jiewei Wu , Pujin Cheng , Zhiyuan Cai , Kenneth K. Y. Wong , Xiaoying Tang

Magnetic Resonance Imaging is a critical imaging modality in clinical diagnosis and research, yet its complexity and heterogeneity hinder scalable, generalizable machine learning. Although foundation models have revolutionized language and…

Traditional methods for tabular classification usually rely on supervised learning from scratch, which requires extensive training data to determine model parameters. However, a novel approach called Prior-Data Fitted Networks (TabPFN) has…

Machine Learning · Computer Science 2024-06-12 Quangao Liu , Wei Yang , Chen Liang , Longlong Pang , Zhuozhang Zou

Multiple Instance Learning (MIL) has demonstrated promise in Whole Slide Image (WSI) classification. However, a major challenge persists due to the high computational cost associated with processing these gigapixel images. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen

Multiple-instance learning (MIL) is a paradigm of machine learning that aims to classify a set (bag) of objects (instances), assigning labels only to the bags. This problem is often addressed by selecting an instance to represent each bag,…

Human-Computer Interaction · Computer Science 2021-12-22 Sonia Castelo , Moacir Ponti , Rosane Minghim

Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…

Computer Vision and Pattern Recognition · Computer Science 2019-10-23 Shaohua Li , Yong Liu , Xiuchao Sui , Cheng Chen , Gabriel Tjio , Daniel Shu Wei Ting , Rick Siow Mong Goh

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A. Fallowfield , Hideki Ueno , Hitoshi Tsuda , David J. Harrison , Hakan Bilen , Timothy J. Kendall

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Medical vision-language pretraining (VLP) that leverages naturally-paired medical image-report data is crucial for medical image analysis. However, existing methods struggle to accurately characterize associations between images and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Xinjie Liang , Xiangyu Li , Fanding Li , Jie Jiang , Qing Dong , Wei Wang , Kuanquan Wang , Suyu Dong , Gongning Luo , Shuo Li

Federated learning (FL) offers a privacy-centric distributed learning framework, enabling model training on individual clients and central aggregation without necessitating data exchange. Nonetheless, FL implementations often suffer from…

Artificial Intelligence · Computer Science 2024-05-13 Rongyu Zhang , Yun Chen , Chenrui Wu , Fangxin Wang , Bo Li

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Multi-modal medical image segmentation plays an essential role in clinical diagnosis. It remains challenging as the input modalities are often not well-aligned spatially. Existing learning-based methods mainly consider sharing trainable…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Jingkun Chen , Wenqi Li , Hongwei Li , Jianguo Zhang

Image feature matching, a foundational task in computer vision, remains challenging for multimodal image applications, often necessitating intricate training on specific datasets. In this paper, we introduce a Unified Feature Matching…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Yide Di , Yun Liao , Hao Zhou , Kaijun Zhu , Qing Duan , Junhui Liu , Mingyu Lu

Visual place recognition is essential for vision-based robot localization and SLAM. Despite the tremendous progress made in recent years, place recognition in changing environments remains challenging. A promising approach to cope with…

Robotics · Computer Science 2023-04-17 Reihaneh Mirjalili , Michael Krawez , Wolfram Burgard

Referring image segmentation is a typical multi-modal task, which aims at generating a binary mask for referent described in given language expressions. Prior arts adopt a bimodal solution, taking images and languages as two modalities…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Zizhang Li , Mengmeng Wang , Jianbiao Mei , Yong Liu

Whole slide image (WSI) classification is a critical task in computational pathology. However, the gigapixel-size of such images remains a major challenge for the current state of deep-learning. Current methods rely on multiple-instance…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Etienne Pochet , Rami Maroun , Roger Trullo

Medical vision-language models enable co-learning and integrating features from medical imaging and clinical text. However, these models are not easy to train and the latent representation space can be complex. Here we propose a novel way…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Che Liu , Sibo Cheng , Chen Chen , Mengyun Qiao , Weitong Zhang , Anand Shah , Wenjia Bai , Rossella Arcucci