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One of the key limitations of Molecular Dynamics simulations is the computational intractability of sampling protein conformational landscapes associated with either large system size or long timescales. To overcome this bottleneck, we…

Biomolecules · Quantitative Biology 2018-07-09 Zahra Shamsi , Kevin J. Cheng , Diwakar Shukla

Linear regression models are useful statistical tools to analyze data sets in several different fields. There are several methods to estimate the parameters of a linear regression model. These methods usually perform under normally…

Methodology · Statistics 2020-08-10 Şenay Özdemir , Yeşim Güney , Yetkin Tuaç , Olcay Arslan

Efficient estimation methods for simultaneous autoregressive (SAR) models with missing data in the response variable have been well-explored in the literature. A common practice is to introduce measurement error into SAR models to separate…

Methodology · Statistics 2024-10-10 Anjana Wijayawardhana , Thomas Suesse , David Gunawan

We introduce a recursive algorithm of conveniently general form for estimating the coefficient of a moving average model of order one and obtain convergence results for both correct and misspecified MA(1) models. The algorithm encompasses…

Statistics Theory · Mathematics 2007-06-13 James L. Cantor , David F. Findley

We consider reinforcement learning in an environment modeled by an episodic, finite, stage-dependent Markov decision process of horizon $H$ with $S$ states, and $A$ actions. The performance of an agent is measured by the regret after…

The proportional hazards model has been extensively used in many fields such as biomedicine to estimate and perform statistical significance testing on the effects of covariates influencing the survival time of patients. The classical…

Statistics Theory · Mathematics 2026-01-16 Hanxuan Ye , Xianyang Zhang , Huijuan Zhou

In this work, we propose a deep learning-based method to perform semiparametric regression analysis for spatially dependent data. To be specific, we use a sparsely connected deep neural network with rectified linear unit (ReLU) activation…

Machine Learning · Statistics 2023-12-19 Kexuan Li , Jun Zhu , Anthony R. Ives , Volker C. Radeloff , Fangfang Wang

This article is dedicated to the estimation of the regression function when the explanatory variable is a weakly dependent process whose correlation coefficient exhibits exponential decay and has a known bounded density function. The…

Statistics Theory · Mathematics 2025-07-17 Karine Bertin , Lisandro Fermin , Miguel Padrino

We introduce a new adjusted residual maximum likelihood method (REML) in the context of producing an empirical Bayes (EB) confidence interval for a normal mean, a problem of great interest in different small area applications. Like other…

Statistics Theory · Mathematics 2014-08-29 Masayo Yoshimori , Partha Lahiri

Spatial autocorrelation coefficients such as Moran's index proved to be an eigenvalue of the spatial correlation matrixes. An eigenvalue represents a kind of characteristic length for quantitative analysis. However, if a spatial correlation…

Physics and Society · Physics 2021-02-04 Yanguang Chen

We propose a specification test for conditional location--scale models based on extremal dependence properties of the standardized residuals. We do so comparing the left-over serial extremal dependence -- as measured by the pre-asymptotic…

Methodology · Statistics 2021-08-05 Yannick Hoga

Compositional data find broad application across diverse fields due to their efficacy in representing proportions or percentages of various components within a whole. Spatial dependencies often exist in compositional data, particularly when…

Methodology · Statistics 2024-03-21 Teo Nguyen , Sarat Moka , Kerrie Mengersen , Benoit Liquet

The lack of reliable automatic evaluation metrics is a major impediment to the development of open-domain dialogue systems. Various reference-based metrics have been proposed to calculate a score between a predicted response and a small set…

Computation and Language · Computer Science 2022-03-17 Jun Gao , Wei Bi , Ruifeng Xu , Shuming Shi

Prompt learning has emerged as an effective technique for fine-tuning large-scale foundation models for downstream tasks. However, conventional prompt learning methods are prone to overfitting and can struggle with out-of-distribution…

Temporal Point Processes (TPP) with partial likelihoods involving a latent structure often entail an intractable marginalization, thus making inference hard. We propose a novel approach to Maximum Likelihood Estimation (MLE) involving…

Machine Learning · Computer Science 2019-12-20 Amrith Setlur , Barnabás Póczós

In regression modelling approach, the main step is to fit the regression line as close as possible to the target variable. In this process most algorithms try to fit all of the data in a single line and hence fitting all parts of target…

Machine Learning · Statistics 2018-05-07 Kumarjit Pathak , Jitin Kapila , Aasheesh Barvey , Nikit Gawande

We develop new tools for formal inference and informal model validation in the analysis of spatial point pattern data. The score test is generalized to a "pseudo-score" test derived from Besag's pseudo-likelihood, and to a class of…

Methodology · Statistics 2012-05-18 Adrian Baddeley , Ege Rubak , Jesper Møller

One of the notorious issues for Reinforcement Learning (RL) is poor sample efficiency. Compared to single agent RL, the sample efficiency for Multi-Agent Reinforcement Learning (MARL) is more challenging because of its inherent partial…

Machine Learning · Computer Science 2024-04-16 Linjie Xu , Zichuan Liu , Alexander Dockhorn , Diego Perez-Liebana , Jinyu Wang , Lei Song , Jiang Bian

We study efficiency improvements in randomized experiments for estimating a vector of potential outcome means using regression adjustment (RA) when there are more than two treatment levels. We show that linear RA which estimates separate…

Econometrics · Economics 2025-01-13 Akanksha Negi , Jeffrey M. Wooldridge

Interval-valued data receives much attention due to its wide applications in the fields of finance, econometrics, meteorology and medicine. However, most regression models developed for interval-valued data assume observations are mutually…

Applications · Statistics 2022-10-31 Tingting Huang