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Concept Bottleneck Models (CBMs) have garnered increasing attention due to their ability to provide concept-based explanations for black-box deep learning models while achieving high final prediction accuracy using human-like concepts.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Lijie Hu , Tianhao Huang , Huanyi Xie , Xilin Gong , Chenyang Ren , Zhengyu Hu , Lu Yu , Ping Ma , Di Wang

Introduction: Deep learning (DL) models can help detect intracranial aneurysms on CTA, but high false positive (FP) rates remain a barrier to clinical translation, despite improvement in model architectures and strategies like detection…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Jisoo Kim , Chu-Hsuan Lin , Alberto Ceballos-Arroyo , Ping Liu , Huaizu Jiang , Shrikanth Yadav , Qi Wan , Lei Qin , Geoffrey S Young

Concept bottleneck models (CBM) aim to improve model interpretability by predicting human level "concepts" in a bottleneck within a deep learning model architecture. However, how the predicted concepts are used in predicting the target…

Machine Learning · Computer Science 2025-04-15 Matthew Shen , Aliyah Hsu , Abhineet Agarwal , Bin Yu

Automated ICD-10 coding from clinical discharge summaries requires models that are both accurate on long-tailed multi-label classification tasks and interpretable to clinicians. Concept Bottleneck Models (CBMs) offer a principled framework…

Machine Learning · Computer Science 2026-05-12 Mohammed Sameer Syed , Xuan Lu

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

Trauma is a significant cause of mortality and disability, particularly among individuals under forty. Traditional diagnostic methods for traumatic injuries, such as X-rays, CT scans, and MRI, are often time-consuming and dependent on…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Liheng Jiang , Xuechun yang , Chang Yu , Zhizhong Wu , Yuting Wang

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Concept Bottleneck Models (CBMs) ground image classification on human-understandable concepts to allow for interpretable model decisions. Crucially, the CBM design inherently allows for human interventions, in which expert users are given…

Machine Learning · Computer Science 2024-08-07 Nishad Singhi , Jae Myung Kim , Karsten Roth , Zeynep Akata

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

Concept Bottleneck Models (CBMs) are interpretable models that route predictions through a layer of human-interpretable concepts. While widely studied in vision and, more recently, in NLP, CBMs remain largely unexplored in multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Pierre Moreau , Emeline Pineau Ferrand , Yann Choho , Benjamin Wong , Annabelle Blangero , Milan Bhan

Concept Bottleneck Models (CBMs) enhance interpretability by introducing a layer of human-understandable concepts between inputs and predictions. While recent methods automate concept generation using Large Language Models (LLMs) and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Delong Zhao , Qiang Huang , Di Yan , Yiqun Sun , Jun Yu

The concept bottleneck model (CBM), as a technique improving interpretability via linking predictions to human-understandable concepts, makes high-risk and life-critical medical image classification credible. Typically, existing CBM methods…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Chunjiang Wang , Kun Zhang , Yandong Liu , Zhiyang He , Xiaodong Tao , S. Kevin Zhou

Early detection of melanoma is crucial for preventing severe complications and increasing the chances of successful treatment. Existing deep learning approaches for melanoma skin lesion diagnosis are deemed black-box models, as they omit…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Cristiano Patrício , João C. Neves , Luís F. Teixeira

The opaque nature of Large Language Models (LLMs) has led to significant research efforts aimed at enhancing their interpretability, primarily through post-hoc methods. More recent in-hoc approaches, such as Concept Bottleneck Models…

Machine Learning · Computer Science 2025-02-20 Or Raphael Bidusa , Shaul Markovitch

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

The widespread adoption of deep learning models in computer vision has intensified concerns about interpretability. Despite strong performance, these models are often treated as black boxes, with limited systematic investigation of their…

Machine Learning · Computer Science 2026-05-13 Konstantinos P. Panousis , Diego Marcos

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Concept bottleneck models (CBMs) are inherently interpretable and intervenable neural network models, which explain their final label prediction by the intermediate prediction of high-level semantic concepts. However, they require target…

Machine Learning · Computer Science 2026-04-06 Shin'ya Yamaguchi , Kosuke Nishida , Daiki Chijiwa , Yasutoshi Ida

Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Erin Rainville , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity…

Signal Processing · Electrical Eng. & Systems 2024-10-14 Kaizhong Zheng , Shujian Yu , Baojuan Li , Robert Jenssen , Badong Chen