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Concept-based explanation methods, such as concept bottleneck models (CBMs), aim to improve the interpretability of machine learning models by linking their decisions to human-understandable concepts, under the critical assumption that such…

Artificial Intelligence · Computer Science 2025-02-03 Halil Ibrahim Aysel , Xiaohao Cai , Adam Prugel-Bennett

Concept bottleneck models (CBMs) are interpretable neural networks that first predict labels for human-interpretable concepts relevant to the prediction task, and then predict the final label based on the concept label predictions. We…

Machine Learning · Computer Science 2023-04-28 Kushal Chauhan , Rishabh Tiwari , Jan Freyberg , Pradeep Shenoy , Krishnamurthy Dvijotham

Concept Bottleneck Models (CBMs) aim for ante-hoc interpretability by learning a bottleneck layer that predicts interpretable concepts before the decision. State-of-the-art approaches typically select which concepts to learn via human…

Machine Learning · Computer Science 2026-03-10 Antonio De Santis , Schrasing Tong , Marco Brambilla , Lalana Kagal

Modern deep neural networks have now reached human-level performance across a variety of tasks. However, unlike humans they lack the ability to explain their decisions by showing where and telling what concepts guided them. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Itay Benou , Tammy Riklin-Raviv

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Concept Bottleneck Models (CBMs) provide explicit interpretations for deep neural networks through concepts and allow intervention with concepts to adjust final predictions. Existing CBMs assume concepts are conditionally independent given…

Machine Learning · Computer Science 2026-05-04 Haotian Xu , Tsui-Wei Weng , Lam M. Nguyen , Tengfei Ma

Concept Bottleneck Models (CBMs) have been proposed as a compromise between white-box and black-box models, aiming to achieve interpretability without sacrificing accuracy. The standard training procedure for CBMs is to predefine a…

Machine Learning · Computer Science 2025-12-05 Jean Feng , Avni Kothari , Luke Zier , Chandan Singh , Yan Shuo Tan

Concept Bottleneck Models (CBMs) have become a popular approach to enable interpretability in neural networks by constraining classifier inputs to a set of human-understandable concepts. While effective, current models embed concepts in…

Machine Learning · Computer Science 2026-05-13 Daniel Uyterlinde , Swasti Shreya Mishra , Pascal Mettes

Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Concept Bottleneck Models (CBMs) aim to enhance interpretability by predicting human-understandable concepts as intermediates for decision-making. However, these models often face challenges in ensuring reliable concept representations,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Yuxuan Cai , Xiyu Wang , Satoshi Tsutsui , Winnie Pang , Bihan Wen

Concept Bottleneck Models (CBMs) tackle the opacity of neural architectures by constructing and explaining their predictions using a set of high-level concepts. A special property of these models is that they permit concept interventions,…

Background:Subarachnoid hemorrhage caused by ruptured cerebral aneurysm often leads to fatal consequences.However,if the aneurysm can be found and treated during asymptomatic periods,the probability of rupture can be greatly reduced.At…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Chen Geng , Meng Chen , Ruoyu Di , Dongdong Wang , Liqin Yang , Wei Xia , Yuxin Li , Daoying Geng

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

Interpreting and explaining the behavior of deep neural networks is critical for many tasks. Explainable AI provides a way to address this challenge, mostly by providing per-pixel relevance to the decision. Yet, interpreting such…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Bowen Wang , Liangzhi Li , Yuta Nakashima , Hajime Nagahara

Information from neuroimaging examinations is increasingly used to support diagnoses of dementia, e.g., Alzheimer's disease. While current clinical practice is mainly based on visual inspection and feature engineering, Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Michael Scheschenja , Joel Wessendorf , Meike Nauta , Vincenzo Positano , Christin Seifert

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Concept bottleneck models (CBMs) are a class of interpretable neural network models that predict the target response of a given input based on its high-level concepts. Unlike the standard end-to-end models, CBMs enable domain experts to…

Machine Learning · Computer Science 2023-07-04 Sungbin Shin , Yohan Jo , Sungsoo Ahn , Namhoon Lee

Catastrophic forgetting remains a fundamental challenge in continual learning, in which models often forget previous knowledge when fine-tuned on a new task. This issue is especially pronounced in class incremental learning (CIL), which is…

Machine Learning · Computer Science 2026-04-17 Amirhosein Javadi , Tuomas Oikarinen , Tara Javidi , Tsui-Wei Weng

Concept Bottleneck Models (CBMs) provide inherent interpretability by first predicting a set of human-understandable concepts and then mapping them to labels through a simple classifier. While users can intervene in the concept space to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Hangzhou He , Lei Zhu , Kaiwen Li , Xinliang Zhang , Jiakui Hu , Ourui Fu , Zhengjian Yao , Yanye Lu