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Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing…

Machine Learning · Computer Science 2026-05-06 He Lyu , Huolin Zeng , Junren Wang , Huazhen Yang , Linchao He , Yong Chen , Zhirui Li , Andreas Maier , Siming Bayer , Huan Song

Robust reinforcement learning agents using high-dimensional observations must be able to identify relevant state features amidst many exogeneous distractors. A representation that captures controllability identifies these state elements by…

Machine Learning · Computer Science 2024-06-25 Max Rudolph , Caleb Chuck , Kevin Black , Misha Lvovsky , Scott Niekum , Amy Zhang

Causal representation learning (CRL) seeks to uncover meaningful latent variables and their corresponding causal structure from high-dimensional observational data. Although its significance, CRL identifiability remains a crucial property,…

Machine Learning · Computer Science 2026-05-20 Manal Benhamza , Marianne Clausel , Myriam Tami

The recent availability of large datasets in bio-medicine has inspired the development of representation learning methods for multiple healthcare applications. Despite advances in predictive performance, the clinical utility of such methods…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Neeraj Wagh , Jionghao Wei , Samarth Rawal , Brent M. Berry , Yogatheesan Varatharajah

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Robust generalization beyond training distributions remains a critical challenge for deep neural networks. This is especially pronounced in medical image analysis, where data is often scarce and covariate shifts arise from different…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Francesco Di Salvo , Sebastian Doerrich , Jonas Alle , Christian Ledig

The classification of gigapixel histopathology images with deep multiple instance learning models has become a critical task in digital pathology and precision medicine. In this work, we propose a Transformer-based multiple instance…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Josef Cersovsky , Sadegh Mohammadi , Dagmar Kainmueller , Johannes Hoehne

The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data across privacy-siloed institutions and substantial heterogeneity…

Machine learning methods can be unreliable when deployed in domains that differ from the domains on which they were trained. There are a wide range of proposals for mitigating this problem by learning representations that are ``invariant''…

Machine Learning · Statistics 2023-02-09 Zihao Wang , Victor Veitch

Recent studies indicate that large multimodal models (LMMs) potentially act as general-purpose assistants and are highly robust against different distributions. Despite this, domain-specific adaptation is still necessary particularly in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Guanglin Zhou , Zhongyi Han , Shiming Chen , Biwei Huang , Liming Zhu , Salman Khan , Xin Gao , Lina Yao

Joint embeddings between medical imaging modalities and associated radiology reports have the potential to offer significant benefits to the clinical community, ranging from cross-domain retrieval to conditional generation of reports to the…

Machine Learning · Computer Science 2018-11-28 Tzu-Ming Harry Hsu , Wei-Hung Weng , Willie Boag , Matthew McDermott , Peter Szolovits

Deep learning has become a promising approach for automated medical diagnoses. When medical data samples are limited, collaboration among multiple institutions is necessary to achieve high algorithm performance. However, sharing patient…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Ken Chang , Niranjan Balachandar , Carson K Lam , Darvin Yi , James M Brown , Andrew Beers , Bruce R Rosen , Daniel L Rubin , Jayashree Kalpathy-Cramer

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Adapting machine learning models to medical time series across different domains remains a challenge due to complex temporal dependencies and dynamic distribution shifts. Current approaches often focus on isolated feature representations,…

Machine Learning · Computer Science 2025-09-23 YongKyung Oh , Alex Bui

Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities,…

Machine Learning · Computer Science 2018-11-13 Brandon Malone , Alberto Garcia-Duran , Mathias Niepert

Effective modeling of electronic health records presents many challenges as they contain large amounts of irregularity most of which are due to the varying procedures and diagnosis a patient may have. Despite the recent progress in machine…

Machine Learning · Computer Science 2019-10-07 Sajad Darabi , Mohammad Kachuee , Majid Sarrafzadeh

Ensuring generalization to unseen environments remains a challenge. Domain shift can lead to substantially degraded performance unless shifts are well-exercised within the available training environments. We introduce a simple robust…

Machine Learning · Computer Science 2021-10-20 Yilun Xu , Tommi Jaakkola

Multimodality Representation Learning, as a technique of learning to embed information from different modalities and their correlations, has achieved remarkable success on a variety of applications, such as Visual Question Answering (VQA),…

Artificial Intelligence · Computer Science 2024-03-04 Muhammad Arslan Manzoor , Sarah Albarri , Ziting Xian , Zaiqiao Meng , Preslav Nakov , Shangsong Liang