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Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

The Segment Anything Model (SAM) is a powerful foundation model that has revolutionised image segmentation. To apply SAM to surgical instrument segmentation, a common approach is to locate precise points or boxes of instruments and then use…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenxi Yue , Jing Zhang , Kun Hu , Yong Xia , Jiebo Luo , Zhiyong Wang

Segmenting 3D objects into parts is a long-standing challenge in computer vision. To overcome taxonomy constraints and generalize to unseen 3D objects, recent works turn to open-world part segmentation. These approaches typically transfer…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Zhe Zhu , Le Wan , Rui Xu , Yiheng Zhang , Honghua Chen , Zhiyang Dou , Cheng Lin , Yuan Liu , Mingqiang Wei

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

The Segment Anything Model (SAM) and CLIP are remarkable vision foundation models (VFMs). SAM, a prompt driven segmentation model, excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero shot recognition…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Sidra Aleem , Fangyijie Wang , Mayug Maniparambil , Eric Arazo , Julia Dietlmeier , Guenole Silvestre , Kathleen Curran , Noel E. O'Connor , Suzanne Little

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

Ocular Toxoplasmosis (OT), is a common eye infection caused by T. gondii that can cause vision problems. Diagnosis is typically done through a clinical examination and imaging, but these methods can be complicated and costly, requiring…

Image and Video Processing · Electrical Eng. & Systems 2023-05-19 Syed Samiul Alam , Samiul Based Shuvo , Shams Nafisa Ali , Fardeen Ahmed , Arbil Chakma , Yeong Min Jang

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Optic disk segmentation is a prerequisite step in automatic retinal screening systems. In this paper, we propose an algorithm for optic disk segmentation based on a local adaptive thresholding method. Location of the optic disk is validated…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Farnoosh Ghadiri , Robert Bergevin , Masoud Shafiee

The Segment Anything Model (SAM), a foundation model for general image segmentation, has demonstrated impressive zero-shot performance across numerous natural image segmentation tasks. However, SAM's performance significantly declines when…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Cheng Chen , Juzheng Miao , Dufan Wu , Zhiling Yan , Sekeun Kim , Jiang Hu , Aoxiao Zhong , Zhengliang Liu , Lichao Sun , Xiang Li , Tianming Liu , Pheng-Ann Heng , Quanzheng Li

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…

Promptable foundation models, particularly Segment Anything Model (SAM), have emerged as a promising alternative to the traditional task-specific supervised learning for image segmentation. However, many evaluation studies have found that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Rachana Sathish , Rahul Venkataramani , K S Shriram , Prasad Sudhakar

While Contrastive Language-Image Pre-training (CLIP) has advanced open-vocabulary predictions, its performance on semantic segmentation remains suboptimal. This shortfall primarily stems from its spatial-invariant semantic features and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Yuheng Shi , Minjing Dong , Chang Xu

Instance segmentation of prohibited items in security X-ray images is a critical yet challenging task. This is mainly caused by the significant appearance gap between prohibited items in X-ray images and natural objects, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Yunhan Ren , Ruihuang Li , Lingbo Liu , Changwen Chen

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Using extensive training data from SA-1B, the Segment Anything Model (SAM) has demonstrated exceptional generalization and zero-shot capabilities, attracting widespread attention in areas such as medical image segmentation and remote…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Quan Zhang , Yuxin Qi , Xi Tang , Jinwei Fang , Xi Lin , Ke Zhang , Chun Yuan

Camouflaged object segmentation presents unique challenges compared to traditional segmentation tasks, primarily due to the high similarity in patterns and colors between camouflaged objects and their backgrounds. Effective solutions to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Wenqi Guo , Mohamed Shehata , Shan Du

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel