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Molecular editing aims to modify a given molecule to optimize desired chemical properties while preserving structural similarity. However, current approaches typically rely on string-based or continuous representations, which fail to…

Machine Learning · Computer Science 2025-05-27 Yuanxin Zhuang , Dazhong Shen , Ying Sun

The ratio of two probability densities, called a density-ratio, is a vital quantity in machine learning. In particular, a relative density-ratio, which is a bounded extension of the density-ratio, has received much attention due to its…

Machine Learning · Statistics 2021-07-05 Atsutoshi Kumagai , Tomoharu Iwata , Yasuhiro Fujiwara

Accurate many-body treatments of condensed-phase systems are challenging because correlated solvers such as full configuration interaction (FCI) and the density matrix renormalization group (DMRG) scale exponentially with system size.…

Short-fiber-reinforced composites (SFRC) are high-performance engineering materials for lightweight structural applications in the automotive and electronics industries. Typically, SFRC structures are manufactured by injection molding,…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Haoyan Wei , C. T. Wu , Wei Hu , Tung-Huan Su , Hitoshi Oura , Masato Nishi , Tadashi Naito , Stan Chung , Leo Shen

The ongoing energy crisis has underscored the urgent need for energy-efficient materials with high energy utilization efficiency, prompting a surge in research into organic compounds due to their environmental compatibility, cost-effective…

Chemical Physics · Physics 2025-07-24 Qi Ou , Hongshuai Wang , Minyang Zhuang , Shangqian Chen , Lele Liu , Ning Wang , Zhifeng Gao

We propose a simple, but efficient and accurate machine learning (ML) model for developing high-dimensional potential energy surface. This so-called embedded atom neural network (EANN) approach is inspired by the well-known empirical…

Chemical Physics · Physics 2019-10-23 Yaolong Zhang , Ce Hu , Bin Jiang

Machine Learning (ML) approximations to Density Functional Theory (DFT) potential energy surfaces (PESs) are showing great promise for reducing the computational cost of accurate molecular simulations, but at present they are not applicable…

Chemical Physics · Physics 2020-03-05 Xiaowei Xie , Kristin A. Persson , David W. Small

The imperative for early detection of type 2 diabetes mellitus (T2DM) is challenged by its asymptomatic onset and dependence on suboptimal clinical diagnostic tests, contributing to its widespread global prevalence. While research into…

Machine Learning · Computer Science 2024-12-17 Sanjana Gundapaneni , Zhuo Zhi , Miguel Rodrigues

Electron density distribution plays an essential role in predicting molecular properties. It is also a simple observable from which machine-learning models for molecular electronic structure can be derived. In the present work, we present…

Chemical Physics · Physics 2022-04-01 Lan Nguyen Tran

Kohn-Sham density functional theory is the base of modern computational approaches to electronic structures. Their accuracy vitally relies on the exchange-correlation energy functional, which encapsulates electron-electron interaction…

Computational Physics · Physics 2019-11-04 Ryo Nagai , Ryosuke Akashi , Osamu Sugino

We propose Cormorant, a rotationally covariant neural network architecture for learning the behavior and properties of complex many-body physical systems. We apply these networks to molecular systems with two goals: learning atomic…

Computational Physics · Physics 2019-11-27 Brandon Anderson , Truong-Son Hy , Risi Kondor

A crucial aspect in the simulation of electrochemical interfaces consists in treating the distribution of electronic charge of electrode materials that are put in contact with an electrolyte solution. Recently, it has been shown how a…

Materials Science · Physics 2024-07-16 Andrea Grisafi , Mathieu Salanne

Machine learning is used to approximate density functionals. For the model problem of the kinetic energy of non-interacting fermions in 1d, mean absolute errors below 1 kcal/mol on test densities similar to the training set are reached with…

Computational Physics · Physics 2015-06-03 John C. Snyder , Matthias Rupp , Katja Hansen , Klaus-Robert Müller , Kieron Burke

Transition metal chromophores with earth-abundant transition metals are an important design target for their applications in lighting and non-toxic bioimaging, but their design is challenged by the scarcity of complexes that simultaneously…

Chemical Physics · Physics 2022-09-16 Chenru Duan , Aditya Nandy , Gianmarco Terrones , David W. Kastner , Heather J. Kulik

The objective of deep metric learning (DML) is to learn embeddings that can capture semantic similarity and dissimilarity information among data points. Existing pairwise or tripletwise loss functions used in DML are known to suffer from…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Xinshao Wang , Yang Hua , Elyor Kodirov , Neil M. Robertson

Split Learning (SL) is a promising Distributed Learning approach in electromyography (EMG) based prosthetic control, due to its applicability within resource-constrained environments. Other learning approaches, such as Deep Learning and…

Machine Learning · Computer Science 2024-05-14 Matea Marinova , Daniel Denkovski , Hristijan Gjoreski , Zoran Hadzi-Velkov , Valentin Rakovic

Understanding the applicability and limitations of electronic-structure methods needs careful and efficient comparison with accurate reference data. Knowledge of the quality and errors of electronic-structure calculations is crucial to…

Gonadotrophin-releasing hormone receptor (GnRH1R) is a promising therapeutic target for the treatment of uterine diseases. To date, several GnRH1R antagonists are available in clinical investigation without satisfying multiple property…

Biomolecules · Quantitative Biology 2022-07-26 Song Li , Song Ke , Chenxing Yang , Jun Chen , Yi Xiong , Lirong Zheng , Hao Liu , Liang Hong

We derive a self-consistent local variant of the Thomas-Fermi approximation for (quasi-)two-dimensional (2D) systems by localizing the Hartree term. The scheme results in an explicit orbital-free representation of the electron density and…

Strongly Correlated Electrons · Physics 2013-02-04 E. Rasanen , S. Pittalis , G. Bekcioglu , I. Makkonen

We demonstrate a machine learning approach designed to extract hidden chemistry/physics to facilitate new materials discovery. In particular, we propose a novel method for learning latent knowledge from material structure data in which…

Materials Science · Physics 2021-08-03 Tien-Cuong Nguyen , Van-Quyen Nguyen , Van-Linh Ngo , Quang-Khoat Than , Tien-Lam Pham
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