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As language models (LMs) are used to build autonomous agents in real environments, ensuring their adversarial robustness becomes a critical challenge. Unlike chatbots, agents are compound systems with multiple components taking actions,…

Machine Learning · Computer Science 2025-02-06 Chen Henry Wu , Rishi Shah , Jing Yu Koh , Ruslan Salakhutdinov , Daniel Fried , Aditi Raghunathan

Practitioners deploying multi-agent large language model (LLM) systems must currently choose between communication topologies such as chain, star, mesh, and richer variants without any pre-inference diagnostic for which topology will…

Multiagent Systems · Computer Science 2026-05-15 Ethan Parks , Dalal Alharthi

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

When are multi-agent LLM systems merely a collection of individual agents versus an integrated collective with higher-order structure? We introduce an information-theoretic framework to test -- in a purely data-driven way -- whether…

Multiagent Systems · Computer Science 2026-04-30 Christoph Riedl

Organisations are starting to adopt LLM-based AI agents, with their deployments naturally evolving from single agents towards interconnected, multi-agent networks. Yet a collection of safe agents does not guarantee a safe collection of…

Multiagent Systems · Computer Science 2025-08-11 Alistair Reid , Simon O'Callaghan , Liam Carroll , Tiberio Caetano

Multi-Agent Policy Gradient (MAPG) has made significant progress in recent years. However, centralized critics in state-of-the-art MAPG methods still face the centralized-decentralized mismatch (CDM) issue, which means sub-optimal actions…

Multiagent Systems · Computer Science 2024-01-17 Xingzhou Lou , Junge Zhang , Timothy J. Norman , Kaiqi Huang , Yali Du

Large Language Model (LLM) agents, which integrate planning, memory, reflection, and tool-use modules, have shown promise in solving complex, multi-step tasks. Yet their sophisticated architectures amplify vulnerability to cascading…

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Graph topology is a fundamental determinant of memory leakage in multi-agent LLM systems, yet its effects remain poorly quantified. We introduce MAMA (Multi-Agent Memory Attack), a framework that measures how network structure shapes…

Cryptography and Security · Computer Science 2026-01-13 Jinbo Liu , Defu Cao , Yifei Wei , Tianyao Su , Yuan Liang , Yushun Dong , Yan Liu , Yue Zhao , Xiyang Hu

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

Computation and Language · Computer Science 2025-11-17 Arsh Gupta , Ajay Narayanan Sridhar , Bonam Mingole , Amulya Yadav

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Argument Mining (AM) is a foundational technology for automated writing evaluation, yet traditional supervised approaches rely heavily on expensive, domain-specific fine-tuning. While Large Language Models (LLMs) offer a training-free…

Computation and Language · Computer Science 2026-03-31 Jakub Bąba , Jarosław A. Chudziak

Rare diseases are challenging to diagnose due to limited patient data and genetic diversity. Despite advances in variant prioritization, many cases remain undiagnosed. While large language models (LLMs) have performed well in medical exams,…

Multidisciplinary team (MDT) consultations are the gold standard for cancer care decision-making, yet current practice lacks structured mechanisms for quantifying consensus and ensuring decision traceability. We introduce a Multi-Agent…

Multiagent Systems · Computer Science 2025-12-17 Xudong Han , Xianglun Gao , Xiaoyi Qu , Zhenyu Yu

The advancement of large language model (LLM) based agents has shifted AI evaluation from single-turn response assessment to multi-step task completion in interactive environments. We present an empirical study evaluating frontier AI models…

Artificial Intelligence · Computer Science 2026-01-15 Logan Ritchie , Sushant Mehta , Nick Heiner , Mason Yu , Edwin Chen

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Computation and Language · Computer Science 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

Artificial Intelligence · Computer Science 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Multi-agent debate (MAD) systems improve LLM reasoning through iterative deliberation, but remain vulnerable to debate collapse, a failure type where final agent decisions are compromised on erroneous reasoning. Existing methods lack…

Multiagent Systems · Computer Science 2026-02-10 Luoxi Tang , Yuqiao Meng , Joseph Costa , Yingxue Zhang , Muchao Ye , Zhaohan Xi

Multi-agent LLM pipelines produce contradictory evidence on whether team diversity improves output quality: heterogeneous Mixture-of-Agents teams outperform single models, yet homogeneous Self-MoA teams consistently win under…

Multiagent Systems · Computer Science 2026-03-24 Artem Maryanskyy
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