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Vision-language models (VLMs) have demonstrated remarkable performance across a wide range of computer-vision tasks, sparking interest in their potential for digital health applications. Here, we apply VLMs to two fundamental challenges in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Victor Li , Naveenraj Kamalakannan , Avinash Parnandi , Heidi Schambra , Carlos Fernandez-Granda

Vision Language Models (VLMs) hold great promise for streamlining labour-intensive medical imaging workflows, yet systematic security evaluations in clinical settings remain scarce. We introduce VSF--Med, an end-to-end vulnerability-scoring…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Binesh Sadanandan , Vahid Behzadan

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area.…

Machine Learning · Computer Science 2024-10-10 Yuwei Zhang , Tong Xia , Aaqib Saeed , Cecilia Mascolo

Vision-Language Models (VLMs) have shown promise in various 2D visual tasks, yet their readiness for 3D clinical diagnosis remains unclear due to stringent demands for recognition precision, reasoning ability, and domain knowledge. To…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

The rapid advancement of pre-trained language models (PLMs) has demonstrated promising results for various code-related tasks. However, their effectiveness in detecting real-world vulnerabilities remains a critical challenge. While existing…

Cryptography and Security · Computer Science 2025-11-25 Youpeng Li , Weiliang Qi , Xuyu Wang , Fuxun Yu , Xinda Wang

Automatic radiology report generation holds significant potential to streamline the labor-intensive process of report writing by radiologists, particularly for 3D radiographs such as CT scans. While CT scans are critical for clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Che Liu , Zhongwei Wan , Yuqi Wang , Hui Shen , Haozhe Wang , Kangyu Zheng , Mi Zhang , Rossella Arcucci

Recently, large language models (LLMs) have taken the spotlight in natural language processing. Further, integrating LLMs with vision enables the users to explore emergent abilities with multimodal data. Visual language models (VLMs), such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Minh-Hao Van , Prateek Verma , Xintao Wu

Data in biology is redundant, noisy, and sparse. How does the type and scale of available data impact model performance? In this work, we specifically investigate how protein language models (pLMs) scale with increasing pretraining data. We…

Quantitative Methods · Quantitative Biology 2025-07-31 Aviv Spinner , Erika DeBenedictis , Corey M. Hudson

This paper presents novel benchmarks for evaluating vision-language models (VLMs) in zero-shot recognition, focusing on granularity and specificity. Although VLMs excel in tasks like image captioning, they face challenges in open-world…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Zhenlin Xu , Yi Zhu , Tiffany Deng , Abhay Mittal , Yanbei Chen , Manchen Wang , Paolo Favaro , Joseph Tighe , Davide Modolo

Evaluating the scientific discovery capabilities of large language model based agents, particularly how they cope with varying environmental complexity and utilize prior knowledge, requires specialized benchmarks currently lacking in the…

Machine Learning · Computer Science 2025-10-28 Yimeng Chen , Piotr Piȩkos , Mateusz Ostaszewski , Firas Laakom , Jürgen Schmidhuber

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Computation and Language · Computer Science 2026-02-11 Pengcheng Qiu , Chaoyi Wu , Junwei Liu , Qiaoyu Zheng , Yusheng Liao , Haowen Wang , Yun Yue , Qianrui Fan , Shuai Zhen , Jian Wang , Jinjie Gu , Yanfeng Wang , Ya Zhang , Weidi Xie

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Protein Language Models (PLMs) such as ESM2 have been shown to be capable of zero-shot prediction of critical scalar properties of proteins (fitness). In this work, we show that injecting a dropout layer at inference time between a PLM's…

Machine Learning · Computer Science 2025-06-19 Aditya Ravuri , Neil D. Lawrence

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

With the advancements in Large Language Models (LLMs), Vision-Language Models (VLMs) have reached a new level of sophistication, showing notable competence in executing intricate cognition and reasoning tasks. However, existing evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Yuanfeng Ji , Chongjian Ge , Weikai Kong , Enze Xie , Zhengying Liu , Zhengguo Li , Ping Luo

Vision-Language Models (VLMs) have emerged as powerful tools for image understanding tasks, yet their practical deployment remains hindered by significant architectural heterogeneity across model families. This paper introduces UVLM…

Machine Learning · Computer Science 2026-03-17 Joan Perez , Giovanni Fusco

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in…

Quantitative Methods · Quantitative Biology 2024-07-09 Yiqing Shen , Zan Chen , Michail Mamalakis , Luhan He , Haiyang Xia , Tianbin Li , Yanzhou Su , Junjun He , Yu Guang Wang

With the rise of Large Language Models (LLMs) and their vision-enabled counterparts (VLMs), numerous works have investigated their capabilities in tasks that fuse the modalities of vision and language. In this work, we benchmark the extent…

Computation and Language · Computer Science 2025-11-18 Tyler Loakman , Joseph James , Chenghua Lin

Vision-Language Models (VLMs) have achieved remarkable progress in complex visual understanding across scientific and reasoning tasks. While performance benchmarking has advanced our understanding of these capabilities, the critical…

Artificial Intelligence · Computer Science 2026-01-27 Asif Azad , Mohammad Sadat Hossain , MD Sadik Hossain Shanto , M Saifur Rahman , Md Rizwan Parvez