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Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heterogeneity. The purpose of this study was to evaluate the…

Quantitative Methods · Quantitative Biology 2019-08-08 Emily E Diller , Sha Cao , Beth Ey , Robert Lober , Jason G Parker

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

Current imaging methods for diagnosing BC are associated with limited sensitivity and specificity and modest positive predictive power. The recent progress in image analysis using artificial intelligence (AI) has created great promise to…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Reza Elahi , Mahdis Nazari

Objectives: High-grade serous ovarian carcinoma (HGSOC) is typically diagnosed at an advanced stage with extensive peritoneal metastases, making treatment challenging. Neoadjuvant chemotherapy (NACT) is often used to reduce tumor burden…

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

This paper proposes to use deep radiomic features (DRFs) from a convolutional neural network (CNN) to model fine-grained texture signatures in the radiomic analysis of recurrent glioblastoma (rGBM). We use DRFs to predict survival of rGBM…

Computer Vision and Pattern Recognition · Computer Science 2019-11-18 Ahmad Chaddad , Saima Rathore , Mingli Zhang , Christian Desrosiers , Tamim Niazi

Background: Nanoparticles can accumulate in solid tumors, serving as diagnostic or therapeutic agents for cancer. Clinical translation is challenging due to low accumulation in tumors and heterogeneity between tumor types and individuals.…

Quantitative Methods · Quantitative Biology 2024-06-17 Jiajia Tang , Jie Zhang , Jiulou Zhang , Yuxia Tang , Hao Ni , Shouju Wang

Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

Cancer grading is an essential task in pathology. The recent developments of artificial neural networks in computational pathology have shown that these methods hold great potential for improving the accuracy and quality of cancer…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Jaeung Lee , Keunho Byeon , Jin Tae Kwak

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

Applications · Statistics 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

Cancer segmentation in whole-slide images is a fundamental step for viable tumour burden estimation, which is of great value for cancer assessment. However, factors like vague boundaries or small regions dissociated from viable tumour areas…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Yibao Sun , Giussepi Lopez , Yaqi Wang , Xingru Huang , Huiyu Zhou , Qianni Zhang

Personalized precision radiation therapy requires more than simple classification, it demands the identification of prognostic, spatially informative features and the ability to adapt treatment based on individual response. This study…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

In the existing research of mammogram image classification, either clinical data or image features of a specific type is considered along with the supervised classifiers such as Neural Network (NN) and Support Vector Machine (SVM). This…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 S. Kavitha , K. K. Thyagharajan

Herein we propose a deep learning-based approach for the prediction of lung lesion response based on radiomic features extracted from clinical CT scans of patients in non-small cell lung cancer trials. The approach starts with the…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Antong Chen , Jennifer Saouaf , Bo Zhou , Randolph Crawford , Jianda Yuan , Junshui Ma , Richard Baumgartner , Shubing Wang , Gregory Goldmacher

In this paper we propose a method for predicting the status of MGMT promoter methylation in high-grade gliomas. From the available MR images, we segment the tumor using deep convolutional neural networks and extract both radiomic features…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Koen Van Leemput

Objective: Radiomics, an emerging tool for medical image analysis, is potential towards precisely characterizing gastric cancer (GC). Whether using one-slice 2D annotation or whole-volume 3D annotation remains a long-time debate, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Lingwei Meng , Di Dong , Xin Chen , Mengjie Fang , Rongpin Wang , Jing Li , Zaiyi Liu , Jie Tian

Breast cancer investigation is of great significance, and developing tumor detection methodologies is a critical need. However, it is a challenging task for breast ultrasound due to the complicated breast structure and poor quality of the…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Fei Xu , Yingtao Zhang , Min Xian , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

Purpose: Chest X-rays are essential for diagnosing pulmonary conditions, but limited access in resource-constrained settings can delay timely diagnosis. Electrocardiograms (ECGs), in contrast, are widely available, non-invasive, and often…

Signal Processing · Electrical Eng. & Systems 2025-09-23 Julia Matejas , Olaf Żurawski , Nils Strodthoff , Juan Miguel Lopez Alcaraz

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

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