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While remarkable advances have been made in Computed Tomography (CT), capturing CT images with non-standardized protocols causes low reproducibility regarding radiomic features, forming a barrier on CT image analysis in a large scale.…
Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…
Breast cancer is a significant public health concern and early detection is critical for triaging high risk patients. Sequential screening mammograms can provide important spatiotemporal information about changes in breast tissue over time.…
Radiomics has shown a capability for different types of cancers such as glioma to predict the clinical outcome. It can have a non-invasive means of evaluating the immunotherapy response prior to treatment. However, the use of deep…
'Radiomics' is a method that extracts mineable quantitative features from radiographic images. These features can then be used to determine prognosis, for example, predicting the development of distant metastases (DM). Existing radiomics…
Objective: Accurately classifying the malignancy of lesions detected in a screening scan is critical for reducing false positives. Radiomics holds great potential to differentiate malignant from benign tumors by extracting and analyzing a…
Recent technological advancements have enabled detailed investigation of associations between the molecular architecture and tumor heterogeneity, through multi-source integration of radiological imaging and genomic (radiogenomic) data. In…
Early diagnosis of pathological invasiveness of pulmonary adenocarcinomas using computed tomography (CT) imaging would alter the course of treatment of adenocarcinomas and subsequently improve the prognosis. Most of the existing systems use…
Quantitative medical image computing (radiomics) has been widely applied to build prediction models from medical images. However, overfitting is a significant issue in conventional radiomics, where a large number of radiomic features are…
Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…
Use expert visualization or conventional clinical indices can lack accuracy for borderline classications. Advanced statistical approaches based on eigen-decomposition have been mostly concerned with shape and motion indices. In this paper,…
Lung cancer is the leading cause of cancer death in the world. Accurate determination of the EGFR (epidermal growth factor receptor) mutation status is highly relevant for the proper treatment of this patients. Purpose: The aim of this…
Purpose: Radiation pneumonitis (RP) is a serious complication of intensity-modulated radiation therapy (IMRT) for breast cancer patients, underscoring the need for precise and explainable predictive models. This study presents an…
Purpose: We aimed to develop a data-driven multiomics approach integrating radiomics, dosiomics, and delta features to predict treatment response at an earlier stage (intra-treatment) for brain metastases (BMs) patients treated with PULSAR.…
Patients with metastatic breast cancer (mBC) undergo continuous medical imaging during treatment, making accurate lesion detection and monitoring over time critical for clinical decisions. Predicting drug response from post-treatment data…
Classical radiomic features are designed to quantify image appearance and intensity patterns. Compared with end-to-end deep learning (DL) models trained for disease classification, radiomics pipelines with low-dimensional parametric…
Radiomics-based machine learning models show promise for clinical decision support but are vulnerable to distribution shifts caused by variations in imaging protocols, positioning, and segmentation. This study systematically investigates…
Predicting clinical outcomes from medical images using quantitative features (``radiomics'') requires many method design choices, Currently, in new clinical applications, finding the optimal radiomics method out of the wide range of methods…
Implicit representation mapping (IRM) can translate image features to any continuous resolution, showcasing its potent capability for ultra-high-resolution image segmentation refinement. Current IRM-based methods for refining…
Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…