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Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

This work studies the challenging problem of acquiring high-quality underwater images via 4-D light field (LF) imaging. To this end, we propose GeoDiff-LF, a novel diffusion-based framework built upon SD-Turbo to enhance underwater 4-D LF…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Yuji Lin , Qian Zhao , Zongsheng Yue , Junhui Hou , Deyu Meng

Diffusion models have achieved remarkable success in image generation but their practical application is often hindered by the slow sampling speed. Prior efforts of improving efficiency primarily focus on compressing models or reducing the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Jiuyi Xu , Qing Jin , Meida Chen , Andrew Feng , Yang Sui , Yangming Shi

Visuomotor imitation learning policies enable robots to efficiently acquire manipulation skills from visual demonstrations. However, as scene complexity and visual distractions increase, policies that perform well in simple settings often…

Artificial Intelligence · Computer Science 2025-11-11 Yuhang Dong , Haizhou Ge , Yupei Zeng , Jiangning Zhang , Beiwen Tian , Hongrui Zhu , Yufei Jia , Ruixiang Wang , Zhucun Xue , Guyue Zhou , Longhua Ma , Guanzhong Tian

Diffusion models have achieved impressive performance on multi-focus image fusion (MFIF). However, a key challenge in applying diffusion models to the ill-posed MFIF problem is that defocus blur can make common symmetric geometric…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Bo Li , Tingting Bao , Lingling Zhang , Weiping Fu , Yaxian Wang , Jun Liu

De novo molecular generation from tandem mass spectra is a challenging inverse problem whose core difficulty lies in the circular dependency between atom-level and bond-level reasoning: determining a bond's type requires knowing its…

Machine Learning · Computer Science 2026-05-11 Xujun Che , Xiuxia Du , Depeng Xu

The goal of scene text image super-resolution is to reconstruct high-resolution text-line images from unrecognizable low-resolution inputs. The existing methods relying on the optimization of pixel-level loss tend to yield text edges that…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Baolin Liu , Zongyuan Yang , Pengfei Wang , Junjie Zhou , Ziqi Liu , Ziyi Song , Yan Liu , Yongping Xiong

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

In clinical practice, tri-modal medical image fusion, compared to the existing dual-modal technique, can provide a more comprehensive view of the lesions, aiding physicians in evaluating the disease's shape, location, and biological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yushen Xu , Xiaosong Li , Yuchan Jie , Haishu Tan

Inverse protein folding generates valid amino acid sequences that can fold into a desired protein structure, with recent deep-learning advances showing strong potential and competitive performance. However, challenges remain, such as…

Biomolecules · Quantitative Biology 2025-07-29 Peizhen Bai , Filip Miljković , Xianyuan Liu , Leonardo De Maria , Rebecca Croasdale-Wood , Owen Rackham , Haiping Lu

Molecular optimization, aimed at improving binding affinity or other molecular properties, is a crucial task in drug discovery that often relies on the expertise of medicinal chemists. Recently, deep learning-based 3D generative models…

Machine Learning · Computer Science 2025-05-01 Anjie Qiao , Junjie Xie , Weifeng Huang , Hao Zhang , Jiahua Rao , Shuangjia Zheng , Yuedong Yang , Zhen Wang , Guo-Bo Li , Jinping Lei

Molecular docking that predicts the bound structures of small molecules (ligands) to their protein targets, plays a vital role in drug discovery. However, existing docking methods often face limitations: they either overlook crucial…

Quantitative Methods · Quantitative Biology 2025-02-24 Zizhuo Zhang , Lijun Wu , Kaiyuan Gao , Jiangchao Yao , Tao Qin , Bo Han

Diffusion probabilistic models have recently achieved remarkable success in generating high-quality images. However, balancing high perceptual quality and low distortion remains challenging in application of diffusion models in image…

Image and Video Processing · Electrical Eng. & Systems 2025-12-23 Juan Song , Jiaxiang He , Lijie Yang , Mingtao Feng , Keyan Wang

Current methods based on deep learning for self-supervised low-dose CT (LDCT) reconstruction, while reducing the dependence on paired data, face the problem of significantly decreased generalization when training with single-dose data and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Guoquan Wei , Liu Shi , Zekun Zhou , Mohan Li , Cunfeng Wei , Wenzhe Shan , Qiegen Liu

Diffusion probabilistic models are traditionally used to generate colors at fixed pixel positions in 2D images. Building on this, we extend diffusion models to point cloud semantic segmentation, where point positions also remain fixed, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Yong He , Hongshan Yu , Mingtao Feng , Tongjia Chen , Zechuan Li , Anwaar Ulhaq , Saeed Anwar , Ajmal Saeed Mian

Federated learning aims at training models collaboratively across participants while protecting privacy. However, one major challenge for this paradigm is the data heterogeneity issue, where biased data preferences across multiple clients,…

Machine Learning · Computer Science 2025-07-21 Huan Wang , Haoran Li , Huaming Chen , Jun Yan , Jiahua Shi , Jun Shen

Virtual try-on (VTON) aims to synthesize realistic images of a person wearing a target garment, with broad applications in e-commerce and digital fashion. While recent advances in latent diffusion models have substantially improved visual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xiang Xu

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu
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