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Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

Deep neural networks have reached remarkable achievements in medical image processing tasks, specifically in classifying and detecting various diseases. However, when confronted with limited data, these networks face a critical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Matina Mahdizadeh Sani , Ali Royat , Mahdieh Soleymani Baghshah

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Ioannis Lagogiannis , Felix Meissen , Georgios Kaissis , Daniel Rueckert

Self-supervised contrastive representation learning offers the advantage of learning meaningful visual representations from unlabeled medical datasets for transfer learning. However, applying current contrastive learning approaches to…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Zeyu Fu , Jianbo Jiao , Robail Yasrab , Lior Drukker , Aris T. Papageorghiou , J. Alison Noble

Image anomaly detection consists in detecting images or image portions that are visually different from the majority of the samples in a dataset. The task is of practical importance for various real-life applications like biomedical image…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Axel De Nardin , Pankaj Mishra , Gian Luca Foresti , Claudio Piciarelli

Being able to adequately process and combine data arising from different sites is crucial in neuroimaging, but is difficult, owing to site, sequence and acquisition-parameter dependent biases. It is important therefore to design algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso

Pelvic diseases in women of reproductive age represent a major global health burden, with diagnosis frequently delayed due to high anatomical variability, complicating MRI interpretation. Existing AI approaches are largely disease-specific…

Convolutional Neural Network (CNN)-based accurate prediction typically requires large-scale annotated training data. In Medical Imaging, however, both obtaining medical data and annotating them by expert physicians are challenging; to…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Changhee Han , Kohei Murao , Shin'ichi Satoh , Hideki Nakayama

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

Neural network-based anomaly detection remains challenging in clinical applications with little or no supervised information and subtle anomalies such as hardly visible brain lesions. Among unsupervised methods, patch-based auto-encoders…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nicolas Pinon , Geoffroy Oudoumanessah , Robin Trombetta , Michel Dojat , Florence Forbes , Carole Lartizien

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

Quantitative Methods · Quantitative Biology 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Automated brain tumour segmentation has the potential of making a massive improvement in disease diagnosis, surgery, monitoring and surveillance. However, this task is extremely challenging. Here, we describe our automated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2020-05-13 Indrajit Mazumdar

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…

This paper addresses the dual challenge of improving anomaly detection and signal integrity in high-speed dynamic random access memory signals. To achieve this, we propose a joint training framework that integrates an autoencoder with a…

Machine Learning · Computer Science 2025-06-24 Muhammad Usama , Hee-Deok Jang , Soham Shanbhag , Yoo-Chang Sung , Seung-Jun Bae , Dong Eui Chang

Classification of heterogeneous diseases is challenging due to their complexity, variability of symptoms and imaging findings. Chronic Obstructive Pulmonary Disease (COPD) is a prime example, being underdiagnosed despite being the third…

Reconstruction-based methods play an important role in unsupervised anomaly detection in images. Ideally, we expect a perfect reconstruction for normal samples and poor reconstruction for abnormal samples. Since the generalizability of deep…

Computer Vision and Pattern Recognition · Computer Science 2021-07-29 Jinlei Hou , Yingying Zhang , Qiaoyong Zhong , Di Xie , Shiliang Pu , Hong Zhou

Unsupervised anomaly detection is a challenging task. Autoencoders (AEs) or generative models are often employed to model the data distribution of normal inputs and subsequently identify anomalous, out-of-distribution inputs by high…

Machine Learning · Computer Science 2025-06-12 Yalin Liao , Austin J. Brockmeier

Homologous anatomical landmarks between medical scans are instrumental in quantitative assessment of image registration quality in various clinical applications, such as MRI-ultrasound registration for tissue shift correction in…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao