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Unsupervised anomaly detection (UAD) aims to detect anomalies without labeled data, a necessity in many machine learning applications where anomalous samples are rare or not available. Most state-of-the-art methods fall into two categories:…

Machine Learning · Computer Science 2025-07-30 Nicolas Pinon , Carole Lartizien

This research proposes a very lightweight model "Fibonacci-Net" along with a novel pooling technique, for automatic brain tumor classification from imbalanced Magnetic Resonance Imaging (MRI) datasets. Automatic brain tumor detection from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Santanu Roy , Ashvath Suresh , Archit Gupta , Shubhi Tiwari , Palak Sahu , Prashant Adhikari , Yuvraj S. Shekhawat

Deep learning models often achieve expert-level accuracy in medical image classification but suffer from a critical flaw: semantic incoherence. These high-confidence mistakes that are semantically incoherent (e.g., classifying a malignant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Abolfazl Mohammadi-Seif , Ricardo Baeza-Yates

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

A commonly adopted approach to carry out detection tasks in medical imaging is to rely on an initial segmentation. However, this approach strongly depends on voxel-wise annotations which are repetitive and time-consuming to draw for medical…

Anomaly detection focuses on identifying samples that deviate from the norm. Discovering informative representations of normal samples is crucial to detecting anomalies effectively. Recent self-supervised methods have successfully learned…

Machine Learning · Computer Science 2025-09-22 Alain Ryser , Thomas M. Sutter , Alexander Marx , Julia E. Vogt

Although neural networks have proven very successful in a number of medical image analysis applications, their use remains difficult when targeting subtle tasks such as the identification of barely visible brain lesions, especially given…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Verónica Muñoz-Ramírez , Nicolas Pinon , Florence Forbes , Carole Lartizen , Michel Dojat

Effective, robust, and automatic tools for brain tumor segmentation are needed for the extraction of information useful in treatment planning from magnetic resonance (MR) images. Context-aware artificial intelligence is an emerging concept…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Iulian Emil Tampu , Neda Haj-Hosseini , Anders Eklund

To develop a domain-agnostic, semi-supervised anomaly detection framework that integrates deep reinforcement learning (DRL) to address challenges such as large-scale data, overfitting, and class imbalance, focusing on brain MRI volumes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Zeduo Zhang , Yalda Mohsenzadeh

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Automated diagnosis from chest CT has improved considerably with deep learning, but models trained on skewed datasets tend to perform unevenly across patient demographics. However, the situation is worse than simple demographic bias. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Justin Li , Daniel Ding , Asmita Yuki Pritha , Aryana Hou , Xin Wang , Shu Hu

Ultrasound is the second most used modality in medical imaging. It is cost effective, hazardless, portable and implemented routinely in numerous clinical procedures. Nonetheless, image quality is characterized by granulated appearance, poor…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Lilach Barkat , Moti Freiman , Haim Azhari

Automatic medical image report generation has drawn growing attention due to its potential to alleviate radiologists' workload. Existing work on report generation often trains encoder-decoder networks to generate complete reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 Jianmo Ni , Chun-Nan Hsu , Amilcare Gentili , Julian McAuley

Accurate fetal brain segmentation is crucial for extracting biomarkers and assessing neurodevelopment, especially in conditions such as corpus callosum dysgenesis (CCD), which can induce drastic anatomical changes. However, the rarity of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Marina Grifell i Plana , Vladyslav Zalevskyi , Léa Schmidt , Yvan Gomez , Thomas Sanchez , Vincent Dunet , Mériam Koob , Vanessa Siffredi , Meritxell Bach Cuadra

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Background and objective: Prior probability shift between training and deployment datasets challenges deep learning-based medical image classification. Standard correction methods reweight posterior probabilities to adjust prior bias, yet…

Quantitative Methods · Quantitative Biology 2025-11-06 Takaaki Tachibana , Toru Nagasaka , Yukari Adachi , Hiroki Kagiyama , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Motion artifacts present a significant challenge in structural MRI (sMRI), often compromising clinical diagnostics and large-scale automated analysis. While manual quality control (QC) remains the gold standard, it is increasingly…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Chinmay Bakhale , Anil Sao