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Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Despite being widely used to support clinical care, general-purpose large multimodal models (LMMs) have generally shown poor or inconclusive performance in medical image interpretation, particularly in pathology, where gigapixel images are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Thomas A. Buckley , Kian R. Weihrauch , Katherine Latham , Andrew Z. Zhou , Padmini A. Manrai , Arjun K. Manrai

Population Based Training (PBT) is a recent approach that jointly optimizes neural network weights and hyperparameters which periodically copies weights of the best performers and mutates hyperparameters during training. Previous PBT…

Artificial Intelligence · Computer Science 2022-02-01 Ang Li , Aleksandra Spyra , Sagi Perel , Valentin Dalibard , Max Jaderberg , Chenjie Gu , David Budden , Tim Harley , Pramod Gupta

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Chromosome analysis is vital for diagnosing genetic disorders and guiding cancer therapy decisions through the identification of somatic clonal aberrations. However, developing an AI model are hindered by the overwhelming complexity and…

Quantitative Methods · Quantitative Biology 2025-05-23 Changchun Yang , Weiqian Dai , Yilan Zhang , Siyuan Chen , Jingdong Hu , Junkai Su , Yuxuan Chen , Ao Xu , Na Li , Xin Gao , Yongguo Yu

Electronic health records contain inconsistently structured or free-text data, requiring efficient preprocessing to enable predictive health care models. Although artificial intelligence-driven natural language processing tools show promise…

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang

Breast cancer is the most widespread neoplasm among women and early detection of this disease is critical. Deep learning techniques have become of great interest to improve diagnostic performance. However, distinguishing between malignant…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Eleonora Lopez , Filippo Betello , Federico Carmignani , Eleonora Grassucci , Danilo Comminiello

In healthcare prediction tasks, it is essential to exploit the correlations between medical features and learn better patient health representations. Existing methods try to estimate feature correlations only from data, or increase the…

Machine Learning · Computer Science 2022-05-24 Xinyu Ma , Xu Chu , Yasha Wang , Hailong Yu , Liantao Ma , Wen Tang , Junfeng Zhao

Purpose: To analyze a recently published chest radiography foundation model for the presence of biases that could lead to subgroup performance disparities across biological sex and race. Materials and Methods: This retrospective study used…

Machine Learning · Computer Science 2023-10-03 Ben Glocker , Charles Jones , Melanie Roschewitz , Stefan Winzeck

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

Language models (LMs) such as BERT and GPT have revolutionized natural language processing (NLP). However, the medical field faces challenges in training LMs due to limited data access and privacy constraints imposed by regulations like the…

Computation and Language · Computer Science 2023-11-14 Le Peng , Gaoxiang Luo , sicheng zhou , jiandong chen , Rui Zhang , Ziyue Xu , Ju Sun

Breast cancer is considered the most critical and frequently diagnosed cancer in women worldwide, leading to an increase in cancer-related mortality. Early and accurate detection is crucial as it can help mitigate possible threats while…

Carcinogenesis is a proteiform phenomenon, with tumors emerging in various locations and displaying complex, diverse shapes. At the crucial intersection of research and clinical practice, it demands precise and flexible assessment. However,…

Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer variability, leading to potential delays or inaccuracies in identifying clinically significant…

Foundation models hold promise for specialized medical imaging tasks, though their effectiveness in breast imaging remains underexplored. This study leverages BiomedCLIP as a foundation model to address challenges in model generalization.…

Computer vision models excel at making predictions when the test distribution closely resembles the training distribution. Such models have yet to match the ability of biological vision to learn from multiple sources and generalize to new…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Tanmay Gupta , Ryan Marten , Aniruddha Kembhavi , Derek Hoiem

Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He