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Diamond containing the negatively charged nitrogen-vacancy (NV) center is emerging as a significant new system for magnetometry. However, most NV sensors require microscopes to collect the fluorescence signals and are therefore limited to…

Transmission electron microscopy (TEM) can be used to successfully determine the structures of proteins. However, such studies are typically done ex situ after extraction of the protein from the cellular environment. Here we describe an…

Biological Physics · Physics 2017-11-07 Michael P. Lake , Louis-S. Bouchard

The negatively-charged NV$^-$-center in diamond has shown great success in nanoscale, high-sensitivity magnetometry. Efficient fluorescence detection is crucial for improving the sensitivity. Furthermore, integrated devices enable…

Solid-state quantum sensors are attracting wide interest because of their exceptional sensitivity at room temperature. In particular, the spin properties of individual nitrogen vacancy (NV) color centers in diamond make it an outstanding…

Understanding the microscopic thermal effects of the hydrogel is important for its application in diverse fields, including thermal-related studies in tissue engineering and thermal management for flexible electronic devices. In recent…

The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…

Instrumentation and Detectors · Physics 2016-08-30 F. Picollo , A. Battiato , E. Carbone , L. Croin , E. Enrico , J. Forneris , S. Gosso , P. Olivero , A. Pasquarelli , V. Carabelli

We demonstrate the tracking of the spin dynamics of ensemble and individual magnetic ferritin proteins from cryogenic up to room temperature using the nitrogen-vacancy color center in diamond as magnetic sensor. We employ different…

Mesoscale and Nanoscale Physics · Physics 2014-11-24 Eike Schäfer-Nolte , Lukas Schlipf , Markus Ternes , Friedemann Reinhard , Klaus Kern , Jörg Wrachtrup

The increasing complexity of advanced semiconductor packages, driven by chiplet architectures and 2.5D/3D integration, challenges conventional failure localization methods such as lock-in thermography (LIT) and complicates current Failure…

Quantum Physics · Physics 2025-12-09 Bartu Bisgin , Marwa Garsi , Andreas Welscher , Michael Hanke , Fleming Bruckmaier

We present an optimized scheme for nanoscale measurements of temperature in a complex environment using the nitrogen-vacancy center in nanodiamonds. To this end we combine a Ramsey measurement utilized to temperature determination with…

Photothermal therapies are based on the optical excitation of plasmonic nanoparticles in the biological environment. The effects of the irradiation on the biological medium depend critically on the heat transfer process at the nanoparticle…

Computational Physics · Physics 2017-11-21 Andrea Torchi , Federica Simonelli , Riccardo Ferrando , Giulia Rossi

Among all materials, mono-crystalline diamond has one of the highest measured thermal conductivities, with values above 2000 W/m/K at room temperature. This stems from momentum-conserving `normal' phonon-phonon scattering processes…

We report on a novel flow-based method for high-precision chemical detection that integrates quantum sensing with droplet microfluidics. We deploy nanodiamond particles hosting fluorescent nitrogen vacancy defects as quantum sensors in…

Fluorescent nanodiamonds are attracting major attention in the field of bio-sensing and biolabeling. In this work we demonstrate a robust approach to surface functionalize individual nanodiamonds with metal-phenolic networks that enhance…

Precise assessment of the mechanical properties of soft biological systems at the nanoscale is crucial for understanding physiology, pathology, and developing relevant drugs. Conventional atomic force microscopy (AFM)-based indentation…

Biological Physics · Physics 2024-08-21 Yue Cui , Weng-Hang Leong , Guoli Zhu , Ren-Bao Liu , Quan Li

Electronic band structures and the Fermi energy provide essential information for understanding the electronic properties of solids. In semiconductors, the Fermi energy level is determined by the donor and acceptor concentrations. For…

Integration of optically-active nanodiamonds with glass fibers is a powerful method of scaling of diamond magnetic sensing functionality. We propose a novel approach for integration of nanodiamonds containing nitrogen-vacancy centers…

We describe how the finite-difference time-domain (FDTD) technique can be used to compute the quasinormal mode (QNM) for metallic nano-resonators, which is important for describing and understanding light-matter interactions in…

Mesoscale and Nanoscale Physics · Physics 2015-01-26 Rong-Chun Ge , S. Hughes

A conformal dispersive finite-difference time-domain (FDTD) method is developed for the study of one-dimensional (1-D) plasmonic waveguides formed by an array of periodic infinite-long silver cylinders at optical frequencies. The curved…

Other Condensed Matter · Physics 2009-11-11 Yan Zhao , Yang Hao

Endoscopic optical imaging using a single multimode fiber (MMF) has emerged as a promising approach for highly compact, minimally invasive, and high-resolution imaging. Unlike conventional fiber bundles, MMF-based endomicroscopes exploit…

Nanodiamonds containing nitrogen-vacancy (NV) centers are promising quantum sensors for biological applications thanks to their sub-micron spatial resolution, biocompatibility, and versatile multi-modal responses. However, the optically…

Applied Physics · Physics 2026-03-23 Shuo Wang , Ming-Zhong Ai , Jing-Wei Fan , Junchen Ye , Chao Lin , Quan Li , Ren-Bao Liu
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