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In the context of the genome-wide association studies (GWAS), one has to solve long sequences of generalized least-squares problems; such a task has two limiting factors: execution time --often in the range of days or weeks-- and data…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-02 Lucas Beyer , Paolo Bientinesi

Single-cell analysis is currently one of the most high-resolution techniques to study biology. The large complex datasets that have been generated have spurred numerous developments in computational biology, in particular the use of…

Genomics · Quantitative Biology 2023-04-27 Ionut Sebastian Mihai , Sarang Chafle , Johan Henriksson

Clustering analysis is fundamental in single-cell RNA sequencing (scRNA-seq) data analysis for elucidating cellular heterogeneity and diversity. Recent graph-based scRNA-seq clustering methods, particularly graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-07-15 Ping Xu , Pengfei Wang , Zhiyuan Ning , Meng Xiao , Min Wu , Yuanchun Zhou

Single-cell RNA sequencing (scRNA-seq) is essential for unraveling cellular heterogeneity and diversity, offering invaluable insights for bioinformatics advancements. Despite its potential, traditional clustering methods in scRNA-seq data…

Machine Learning · Computer Science 2025-10-01 Ping Xu , Zhiyuan Ning , Meng Xiao , Guihai Feng , Xin Li , Yuanchun Zhou , Pengfei Wang

The self-join finds all objects in a dataset that are within a search distance, epsilon, of each other; therefore, the self-join is a building block of many algorithms. We advance a GPU-accelerated self-join algorithm targeted towards high…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Michael Gowanlock , Ben Karsin

Simulators are a primary tool in computer architecture research but are extremely computationally intensive. Simulating modern architectures with increased core counts and recent workloads can be challenging, even on modern hardware. This…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-27 Rodrigo Huerta , Antonio González

Hash tables are ubiquitous. Properties such as an amortized constant time complexity for insertion and querying as well as a compact memory layout make them versatile associative data structures with manifold applications. The rapidly…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-13 Daniel Jünger , Robin Kobus , André Müller , Christian Hundt , Kai Xu , Weiguo Liu , Bertil Schmidt

Graph-based ANNS algorithms have gained increasing research interest and market adoption due to their efficiency and accuracy in retrieval. Existing approaches primarily rely on CPUs for graph index construction and retrieval, but this…

Databases · Computer Science 2026-05-12 Lan Lu , Peiqi Yin , Isaac Yang , Tao Luo , Hua Fan , Wenchao Zhou , Feifei Li , Boon Thau Loo

Computational biology has increasingly turned to agent-based modeling to explore complex biological systems. Biological diffusion (diffusion, decay, secretion, and uptake) is a key driver of biological tissues. GPU computing can vastly…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-27 Matt Stack , Paul Macklin , Robert Searles , Sunita Chandrasekaran

Simulations of physical phenomena are essential to the expedient design of precision components in aerospace and other high-tech industries. These phenomena are often described by mathematical models involving partial differential equations…

Computational Physics · Physics 2017-01-05 Daniel Magee , Kyle E Niemeyer

Latent Dirichlet Allocation(LDA) is a popular topic model. Given the fact that the input corpus of LDA algorithms consists of millions to billions of tokens, the LDA training process is very time-consuming, which may prevent the usage of…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-03-14 Xiaolong Xie , Yun Liang , Xiuhong Li , Wei Tan

This paper introduces sTiles, a GPU-accelerated framework for factorizing sparse structured symmetric matrices. By leveraging tile algorithms for fine-grained computations, sTiles uses a structure-aware task execution flow to handle…

Performance · Computer Science 2025-01-07 Esmail Abdul Fattah , Hatem Ltaief , Havard Rue , David Keyes

Real-time trajectory optimization for nonlinear constrained autonomous systems is critical and typically performed by CPU-based sequential solvers. Specifically, reliance on global sparse linear algebra or the serial nature of dynamic…

Robotics · Computer Science 2026-03-13 Yilin Zou , Zhong Zhang , Maxime Robic , Fanghua Jiang

A modern graphics processing unit (GPU) is able to perform massively parallel scientific computations at low cost. We extend our implementation of the checkerboard algorithm for the two dimensional Ising model [T. Preis et al., J. Comp.…

Computational Physics · Physics 2010-07-22 Benjamin Block , Peter Virnau , Tobias Preis

Restricted solid on solid surface growth models can be mapped onto binary lattice gases. We show that efficient simulation algorithms can be realized on GPUs either by CUDA or by OpenCL programming. We consider a deposition/evaporation…

Computational Physics · Physics 2015-03-17 Henrik Schulz , Géza Ódor , Gergely Ódor , Máté Ferenc Nagy

Recent decades have witnessed the tremendous development of network science, which indeed brings a new and insightful language to model real systems of different domains. Betweenness, a widely employed centrality in network science, is a…

Social and Information Networks · Computer Science 2017-01-24 Rui Fan , Ke Xu , Jichang Zhao

Open-source simulation tools play a crucial role for neuromorphic application engineers and hardware architects to investigate performance bottlenecks and explore design optimizations before committing to silicon. Reconfigurable…

Emerging Technologies · Computer Science 2024-04-26 Sahil Hassan , Michael Inouye , Miguel C. Gonzalez , Ilkin Aliyev , Joshua Mack , Maisha Hafiz , Ali Akoglu

Computational Fluid Dynamics (CFD) is the simulation of fluid flow undertaken with the use of computational hardware. The underlying equations are computationally challenging to solve and necessitate high performance computing (HPC) to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-04 Zachary Cooper-Baldock , Brenda Vara Almirall , Kiao Inthavong

Online analytical processing of queries on datasets in the many-terabyte range is only possible with costly distributed computing systems. To decrease the cost and increase the throughput, systems can leverage accelerators such as GPUs,…

The convex hull is a fundamental geometrical structure for many applications where groups of points must be enclosed or represented by a convex polygon. Although efficient sequential convex hull algorithms exist, and are constantly being…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-27 Alan Keith , Héctor Ferrada , Cristóbal A. Navarro