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We model intracellular regulatory dynamics with threshold-type state-dependent delay and investigate the effect of the state-dependent diffusion time. A general model which is an extension of the classic differential equation models with…

Dynamical Systems · Mathematics 2018-03-13 Qingwen Hu

We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters we have found three phase transitions with one…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Stauffer , S. Cebrat

In this research, we present a generalized quasispecies model in which population growth is governed by an arbitrary nonlinear function incorporating time delays. We begin by demonstrating that, under the constant population constraint, the…

Dynamical Systems · Mathematics 2025-08-19 Nolbert Morales , Edward A. Turner

We propose a model of multispecies populations surviving on distributed resources. System dynamics are investigated under changes in abiotic factors such as the climate, as parameterized through environmental temperature. In particular, we…

Populations and Evolution · Quantitative Biology 2017-10-25 I. Sudakov , S. A. Vakulenko , D. Kirievskaya , K. M. Golden

CRISPR is a newly discovered prokaryotic immune system. Bacteria and archaea with this system incorporate genetic material from invading viruses into their genomes, providing protection against future infection by similar viruses. The…

Populations and Evolution · Quantitative Biology 2017-08-18 Pu Han , Michael W. Deem

The idea of a metapopulation has become canonical in ecology. Its original mean field form provides the important intuition that migration and extinction interact to determine the dynamics of a population composed of subpopulations. From…

Populations and Evolution · Quantitative Biology 2021-07-01 John Vandermeer , Zachary Hajian-Forooshani

We study large deviation events in the timing of disease recurrence. In particular, we are interested in modeling cancer treatment failure due to mutation-induced drug resistance. We first present a two-type branching process model of this…

Probability · Mathematics 2021-08-06 Pranav Hanagal , Kevin Leder , Zicheng Wang

A model to simulate the phenomenon of random lasing is presented. It couples Maxwell's equations with the rate equations of electronic population in a disordered system. Finite difference time domain methods are used to obtain the field…

Disordered Systems and Neural Networks · Physics 2009-10-31 Xunya Jiang , C. M. Soukoulis

The question of whether a population will persist or go extinct is of key interest throughout ecology and biology. Various mathematical techniques allow us to generate knowledge regarding individual behaviour, which can be analysed to…

Populations and Evolution · Quantitative Biology 2021-04-28 Stuart T. Johnston , Matthew J. Simpson , Edmund J. Crampin

Models of many-species ecosystems, such as the Lotka-Volterra and replicator equations, suggest that these systems generically exhibit near-extinction processes, where population sizes go very close to zero for some time before rebounding,…

Statistical Mechanics · Physics 2023-03-15 Thibaut Arnoulx de Pirey , Guy Bunin

We consider the contact process with infection rate $\lambda$ on a random $(d+1)$-regular graph with $n$ vertices, $G_n$. We study the extinction time $\tau_{G_n}$ (that is, the random amount of time until the infection disappears) as $n$…

Probability · Mathematics 2014-05-06 Jean-Christophe Mourrat , Daniel Valesin

This paper investigates biological models that represent the transition equation from a system in the past to a system in the future. It is shown that finite-time Lyapunov exponents calculated along a locally pullback attractive solution…

Dynamical Systems · Mathematics 2024-02-19 Jesús Dueñas , Iacopo P. Longo , Rafael Obaya

During recent years, the study of long transients has been expanded in ecological theory to account for shifts in long-term behavior of ecological systems. These long transients may lead to regime shifts between alternative states that…

Populations and Evolution · Quantitative Biology 2023-05-02 Jorge Arroyo-Esquivel , Alan Hastings , Marissa L Baskett

Mutations can arise from the chance misincorporation of nucleotides during DNA replication or from DNA lesions that are not repaired correctly. We introduce a model that relates the source of mutations to their accumulation with cell…

Populations and Evolution · Quantitative Biology 2015-07-27 Ziyue Gao , Minyoung J. Wyman , Guy Sella , Molly Przeworski

In this paper we consider two continuous-mass population models as analogues of logistic branching random walks, one is supported on a finite trait space and the other one is supported on an infinite trait space. For the first model with…

Probability · Mathematics 2013-04-18 Anton Bovier , Shi-Dong Wang

Rate-induced tipping occurs when a ramp parameter changes rapidly enough to cause the system to tip between co-existing, attracting states. We show that the addition of noise to the system can cause it to tip well below the critical rate at…

Dynamical Systems · Mathematics 2023-01-25 Katherine Slyman , Christopher K. Jones

Asynchronous replication of the genome has been associated with different rates of point mutation and copy number variation (CNV) in human populations. Here, we explored if the bias in the generation of CNV that is associated to DNA…

Genomics · Quantitative Biology 2013-11-27 David Juan , Daniel Rico , Tomas Marques-Bonet , Oscar Fernandez-Capetillo , Alfonso Valencia

This paper deals with an impulsive degenerate logistic model, where pulses are introduced for modeling interventions or disturbances, and degenerate logistic term may describe refugees or protections zones for the species. Firstly, the…

Populations and Evolution · Quantitative Biology 2024-02-20 Willian Cintra , Zhigui Lin , Carlos Alberto Santos , Phyu Phyu Win

Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the…

Biological Physics · Physics 2020-05-19 Yusuke Himeoka , Namiko Mitarai

The existence of anticipatory, complete and lag synchronization in a single system having two different time-delays, that is feedback delay $\tau_1$ and coupling delay $\tau_2$, is identified. The transition from anticipatory to complete…

Chaotic Dynamics · Physics 2009-11-10 D. V. Senthilkumar , M. Lakshmanan