Related papers: D3LM: A Discrete DNA Diffusion Language Model for …

Diffusion language models (DLMs) are an attractive alternative to autoregressive models because they promise sublinear-time, parallel generation, yet practical gains remain elusive as high-quality samples still demand hundreds of refinement…

This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA sequences, and Absorb-Escape, a post-training algorithm…

We propose TraceRL, a trajectory-aware reinforcement learning framework for diffusion language models (DLMs) that incorporates preferred inference trajectory into post-training, and is applicable across different architectures. Equipped…

3D molecule generation is crucial for drug discovery and material design. While prior efforts focus on 3D diffusion models for their benefits in modeling continuous 3D conformers, they overlook the advantages of 1D SELFIES-based Language…

Diffusion models have emerged as a powerful class of generative models, achieving state-of-the-art results in continuous data domains such as image and video generation. Their core mechanism involves a forward diffusion process that…

Diffusion Language Models (DLMs) present a compelling alternative to autoregressive models, offering flexible, any-order infilling without specialized prompting design. However, their practical utility is blocked by a critical limitation:…

Autoregressive (AR) generation is the standard decoding paradigm for Large Language Models (LLMs), but its token-by-token nature limits parallelism at inference time. Diffusion Language Models (DLLMs) offer parallel decoding by recovering…

Large language models (LLMs) have revolutionized natural language processing and are increasingly applied to other sequential data types, including genetic sequences. However, adapting LLMs to genomics presents significant challenges.…

Diffusion large language models (dLLMs) have emerged as a new architecture following auto regressive models. Their denoising process offers a powerful generative advantage, but they present significant challenges in learning and…

Masked language modelling (MLM) as a pretraining objective has been widely adopted in genomic sequence modelling. While pretrained models can successfully serve as encoders for various downstream tasks, the distribution shift between…

We present LLaDA2.0-Uni, a unified discrete diffusion large language model (dLLM) that supports multimodal understanding and generation within a natively integrated framework. Its architecture combines a fully semantic discrete tokenizer, a…

Masked diffusion language models (MDLMs) offer the potential for parallel token generation, but most open-source MDLMs decode fewer than 5 tokens per model forward pass even with sophisticated sampling strategies, limiting their parallel…

Recently, continuous diffusion models (CDM) have been introduced into non-autoregressive (NAR) text-to-text generation. However, the discrete nature of text increases the difficulty of CDM to generate coherent and fluent texts, and also…

Embedding models are a fundamental component of modern AI systems such as semantic search and retrieval-augmented generation. Recent advances in large foundation models have substantially accelerated the development of embedding models,…

Diffusion Language Models (DLMs) offer a promising parallel generation paradigm but suffer from slow inference due to numerous refinement steps and the inability to use standard KV caching. We introduce CDLM (Consistency Diffusion Language…

Large language models (LLMs) trained on text demonstrated remarkable results on natural language processing (NLP) tasks. These models have been adapted to decipher the language of DNA, where sequences of nucleotides act as "words" that…

Although diffusion language models (DLMs) are evolving quickly, many recent models converge on a set of shared components. These components, however, are distributed across ad-hoc research codebases or lack transparent implementations,…

Recent 3D human generative models have achieved remarkable progress by learning 3D-aware GANs from 2D images. However, existing 3D human generative methods model humans in a compact 1D latent space, ignoring the articulated structure and…

Diffusion large language models (dLLMs) are compelling alternatives to autoregressive (AR) models because their denoising models operate over the entire sequence. The global planning and iterative refinement features of dLLMs are…

Recent advances in self-supervised models for natural language, vision, and protein sequences have inspired the development of large genomic DNA language models (DNALMs). These models aim to learn generalizable representations of diverse…