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Large Language Models (LLMs) have recently emerged as planners for language-instructed agents, generating sequences of actions to accomplish natural language tasks. However, their reliability remains a challenge, especially in long-horizon…

Robotics · Computer Science 2025-11-11 Jun Wang , Yevgeniy Vorobeychik , Yiannis Kantaros

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

Artificial Intelligence · Computer Science 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Pre-trained Language Models (PLMs) have achieved remarkable performance for various language understanding tasks in IR systems, which require the fine-tuning process based on labeled training data. For low-resource scenarios, prompt-based…

Computation and Language · Computer Science 2022-04-04 Ziyun Xu , Chengyu Wang , Minghui Qiu , Fuli Luo , Runxin Xu , Songfang Huang , Jun Huang

Unlocking the next generation of biotechnology and therapeutic innovation demands overcoming the inherent complexity and resource-intensity of conventional protein engineering methods. Recent GenAI-powered computational techniques often…

User modeling in large e-commerce platforms aims to optimize user experiences by incorporating various customer activities. Traditional models targeting a single task often focus on specific business metrics, neglecting the comprehensive…

Information Retrieval · Computer Science 2025-02-28 Mingdai Yang , Fan Yang , Yanhui Guo , Shaoyuan Xu , Tianchen Zhou , Yetian Chen , Simone Shao , Jia Liu , Yan Gao

Large Language Models (LLMs) trained on web-scale text corpora have been shown to capture world knowledge in their parameters. However, the mechanism by which language models store different types of knowledge is poorly understood. In this…

Computation and Language · Computer Science 2024-11-08 Jared Fernandez , Yonatan Bisk , Emma Strubell

KEPLMs are pre-trained models that utilize external knowledge to enhance language understanding. Previous language models facilitated knowledge acquisition by incorporating knowledge-related pre-training tasks learned from relation triples…

Computation and Language · Computer Science 2024-03-19 Junbing Yan , Chengyu Wang , Taolin Zhang , Xiaofeng He , Jun Huang , Longtao Huang , Hui Xue , Wei Zhang

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

Biomolecules · Quantitative Biology 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein functions. Recent sequence representation learning methods based on Protein Language Models (PLMs) excel in sequence-based…

Quantitative Methods · Quantitative Biology 2023-10-19 Zuobai Zhang , Chuanrui Wang , Minghao Xu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

The mainstream paradigm behind continual learning has been to adapt the model parameters to non-stationary data distributions, where catastrophic forgetting is the central challenge. Typical methods rely on a rehearsal buffer or known task…

Machine Learning · Computer Science 2022-03-23 Zifeng Wang , Zizhao Zhang , Chen-Yu Lee , Han Zhang , Ruoxi Sun , Xiaoqi Ren , Guolong Su , Vincent Perot , Jennifer Dy , Tomas Pfister

Large language models (LLMs) are routinely pre-trained on billions of tokens, only to start the process over again once new data becomes available. A much more efficient solution is to continually pre-train these models, saving significant…

The study investigates the efficacy of pre-trained language models (PLMs) in analyzing argumentative moves in a longitudinal learner corpus. Prior studies on argumentative moves often rely on qualitative analysis and manual coding, limiting…

Computation and Language · Computer Science 2025-06-04 Wenjuan Qin , Weiran Wang , Yuming Yang , Tao Gui

Language Models are the underpin of all modern Natural Language Processing (NLP) tasks. The introduction of the Transformers architecture has contributed significantly into making Language Modeling very effective across many NLP task,…

Computation and Language · Computer Science 2021-11-05 Nikolaos Stylianou , Ioannis Vlahavas

The remarkable success of pretrained language models has motivated the study of what kinds of knowledge these models learn during pretraining. Reformulating tasks as fill-in-the-blanks problems (e.g., cloze tests) is a natural approach for…

Computation and Language · Computer Science 2020-11-10 Taylor Shin , Yasaman Razeghi , Robert L. Logan , Eric Wallace , Sameer Singh

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

Large language models (LLMs) still grapple with complex tasks like mathematical reasoning. Despite significant efforts invested in improving prefix prompts or reasoning process, the crucial role of problem context might have been neglected.…

Computation and Language · Computer Science 2024-03-28 Haoran Liao , Jidong Tian , Shaohua Hu , Hao He , Yaohui Jin

Recent advancements in vision-language models (VLMs), such as CLIP, have demonstrated substantial success in self-supervised representation learning for vision tasks. However, effectively adapting VLMs to downstream applications remains…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Conventional predictive modeling of parametric relationships in manufacturing processes is limited by the subjectivity of human expertise and intuition on the one hand and by the cost and time of experimental data generation on the other…

Computation and Language · Computer Science 2025-06-26 Kiarash Naghavi Khanghah , Anandkumar Patel , Rajiv Malhotra , Hongyi Xu

As the applications of large language models (LLMs) expand across diverse fields, the ability of these models to adapt to ongoing changes in data, tasks, and user preferences becomes crucial. Traditional training methods, relying on static…

Machine Learning · Computer Science 2024-06-11 Junhao Zheng , Shengjie Qiu , Chengming Shi , Qianli Ma

Over recent years, an increasing amount of compute and data has been poured into training large language models (LLMs), usually by doing one-pass learning on as many tokens as possible randomly selected from large-scale web corpora. While…

Computation and Language · Computer Science 2023-08-24 Kushal Tirumala , Daniel Simig , Armen Aghajanyan , Ari S. Morcos