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Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

Weakly supervised image segmentation with image-level labels has drawn attention due to the high cost of pixel-level annotations. Traditional methods using Class Activation Maps (CAMs) often highlight only the most discriminative regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qingchen Tang , Lei Fan , Maurice Pagnucco , Yang Song

Multimodal image fusion (MMIF) integrates information from different modalities to obtain a comprehensive image, aiding downstream tasks. However, existing research focuses on complementary information fusion and training strategies,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Dan He , Guofen Wang , Weisheng Li , Yucheng Shu , Wenbo Li , Lijian Yang , Yuping Huang , Feiyan Li

Autoencoders represent an effective approach for computing the underlying factors characterizing datasets of different types. The latent representation of autoencoders have been studied in the context of enabling interpolation between data…

Machine Learning · Computer Science 2020-10-23 Alon Oring , Zohar Yakhini , Yacov Hel-Or

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

We propose Motion-Compensated Latent Semantic Canvases (MCLSC) for visual situational awareness on resource-constrained edge devices. The core idea is to maintain persistent semantic metadata in two latent canvases - a slowly accumulating…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Igor Lodin , Sergii Filatov , Vira Filatova , Dmytro Filatov

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Khang Le , Anh Mai Vu , Thi Kim Trang Vo , Ha Thach , Ngoc Bui Lam Quang , Thanh-Huy Nguyen , Minh H. N. Le , Zhu Han , Chandra Mohan , Hien Van Nguyen

The primary goal of continual learning (CL) task in medical image segmentation field is to solve the "catastrophic forgetting" problem, where the model totally forgets previously learned features when it is extended to new categories…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Qian Chen , Lei Zhu , Hangzhou He , Xinliang Zhang , Shuang Zeng , Qiushi Ren , Yanye Lu

Current image compression models often require separate models for each quality level, making them resource-intensive in terms of both training and storage. To address these limitations, we propose an innovative approach that utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Ayman A. Ameen , Thomas Richter , André Kaup

Zero-shot learning holds tremendous potential for histopathology image analysis by enabling models to generalize to unseen classes without extensive labeled data. Recent advancements in vision-language models (VLMs) have expanded the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

Virtual immunohistochemistry (IHC) aims to computationally synthesize molecular staining patterns from routine Hematoxylin and Eosin (H\&E) images, offering a cost-effective and tissue-efficient alternative to traditional physical staining.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Rongze Ma , Mengkang Lu , Zhenyu Xiang , Yongsheng Pan , Yicheng Wu , Qingjie Zeng , Yong Xia

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Automated blood morphology analysis can support hematological diagnostics in low- and middle-income countries (LMICs) but remains sensitive to dataset shifts from staining variability, imaging differences, and rare morphologies. Building…

Machine Learning · Computer Science 2026-01-08 Gabriel Ansah , Eden Ruffell , Delmiro Fernandez-Reyes , Petru Manescu

We propose a CNN based technique that aggregates feature maps from its multiple layers that can localize abnormalities with greater details as well as predict pathology under consideration. Existing class activation mapping (CAM) techniques…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Sumeet Shinde , Tanay Chougule , Jitender Saini , Madhura Ingalhalikar

Anomaly detection in medical imaging is essential for identifying rare pathological conditions, particularly when annotated abnormal samples are limited. We propose a hybrid anomaly detection framework that integrates self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Pritam Kar , Gouri Lakshmi S , Saptarshi Bej

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng