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Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Traditional staining normalization approaches, e.g. Macenko, typically rely on the choice of a single representative reference image, which may not adequately account for the diverse staining patterns of datasets collected in practical…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Desislav Ivanov , Carlo Alberto Barbano , Marco Grangetto

Continual learning (CL) is essential for deploying medical image segmentation models in clinical environments where imaging domains, anatomical targets, and diagnostic tasks evolve over time. However, continual segmentation still faces…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Bomin Wang , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

We consider machine-learning-based malignancy prediction and lesion identification from clinical dermatological images, which can be indistinctly acquired via smartphone or dermoscopy capture. Additionally, we do not assume that images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Meng Xia , Meenal K. Kheterpal , Samantha C. Wong , Christine Park , William Ratliff , Lawrence Carin , Ricardo Henao

Unsupervised image complexity representation often suffers from bias in positive sample selection and sensitivity to image content. We propose CLICv2, a contrastive learning framework that enforces content invariance for complexity…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Shipeng Liu , Liang Zhao , Dengfeng Chen

The lack of well-annotated datasets in computational pathology (CPath) obstructs the application of deep learning techniques for classifying medical images. %Since pathologist time is expensive, dataset curation is intrinsically difficult.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Ryan Zhang , Jiadai Zhu , Stephen Yang , Mahdi S. Hosseini , Angelo Genovese , Lina Chen , Corwyn Rowsell , Savvas Damaskinos , Sonal Varma , Konstantinos N. Plataniotis

Learned image compression (LIC) methods have exhibited promising progress and superior rate-distortion performance compared with classical image compression standards. Most existing LIC methods are Convolutional Neural Networks-based…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Jinming Liu , Heming Sun , Jiro Katto

Calcified plaque in the aorta and pelvic arteries is associated with coronary artery calcification and is a strong predictor of heart attack. Current calcified plaque detection models show poor generalizability to different domains (ie.…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Yingying Zhu , Daniel C. Elton , Sungwon Lee , Perry J. Pickhardt , Ronald M. Summers

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Accuracy and consistency are two key factors in computer-assisted magnetic resonance (MR) image analysis. However, contrast variation from site to site caused by lack of standardization in MR acquisition impedes consistent measurements. In…

Image and Video Processing · Electrical Eng. & Systems 2021-03-25 Lianrui Zuo , Blake E. Dewey , Aaron Carass , Yihao Liu , Yufan He , Peter A. Calabresi , Jerry L. Prince

Context modeling is essential in learned image compression for accurately estimating the distribution of latents. While recent advanced methods have expanded context modeling capacity, they still struggle to efficiently exploit long-range…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Yuqi Li , Haotian Zhang , Li Li , Dong Liu

Multi-label classification (MLC) studies the problem where each instance is associated with multiple relevant labels, which leads to the exponential growth of output space. MLC encourages a popular framework named label compression (LC) for…

Machine Learning · Computer Science 2020-09-21 Jiaqi Lv , Tianran Wu , Chenglun Peng , Yunpeng Liu , Ning Xu , Xin Geng

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

An often overlooked problem in medical image segmentation research is the effective selection of training subsets to annotate from a complete set of unlabelled data. Many studies select their training sets at random, which may lead to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Stephen Lloyd-Brown , Susan Francis , Caroline Hoad , Penny Gowland , Karen Mullinger , Andrew French , Xin Chen

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

Semi-supervised learning is of great significance in medical image segmentation by exploiting unlabeled data. Among its strategies, the co-training framework is prominent. However, previous co-training studies predominantly concentrate on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Pengcheng Zhou , Lantian Zhang , Wei Li

In recent years, a standard computational pathology workflow has emerged where whole slide images are cropped into tiles, these tiles are processed using a foundation model, and task-specific models are built using the resulting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Eric Zimmermann , Julian Viret , Michal Zelechowski , James Brian Hall , Neil Tenenholtz , Adam Casson , George Shaikovski , Eugene Vorontsov , Siqi Liu , Kristen A Severson