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Optical speckle patterns have been widely used for illumination in computational imaging, optical sectioning microscopy, and super-resolution imaging. However, commonly used speckles satisfy Rayleigh statistics, which are not ideal for…

Time-resolved photoluminescence (PL) is commonly used to track dynamics in a broad range of materials. Thus, the search for simplification of the acquisition of PL kinetics attracts continuous attention. This paper presents a new robust and…

Instrumentation and Detectors · Physics 2020-04-22 Jiri Junek , Lukas Ondic , Karel Zidek

Improving the resolution of fluorescence microscopy beyond the diffraction limit can be achievedby acquiring and processing multiple images of the sample under different illumination conditions.One of the simplest techniques, Random…

Many imaging applications require increasingly bright illumination sources, motivating the replacement of conventional thermal light sources with light emitting diodes (LEDs), superluminescent diodes (SLDs) and lasers. Despite their…

Optics · Physics 2017-04-05 Brandon Redding , Michael A. Choma , Hui Cao

Speckle patterns have been widely used in imaging techniques such as ghost imaging, dynamic speckle illumination microscopy, structured illumination microscopy, and photoacoustic fluctuation imaging. Recent advances in the ability to…

Optics · Physics 2021-05-28 Nicholas Bender , Mengyuan Sun , Hasan Yilmaz , Joerg Bewersdorf , Hui Cao

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

Optics · Physics 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller

We demonstrate speckle noise reduction in an in-line holographic imaging system using a Zwitterion-doped liquid crystal dynamic scatterer (LCDS) cell diffuser. Integrated into a minimally modified bright-field microscope, the LCDS actively…

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Laser speckle, the granular intensity pattern arising from random optical interference, provides a high-dimensional encoding of spectral information that can be exploited for precision metrology. Speckle-based spectrometers have advanced…

We experimentally generate speckle patterns with non-Rayleigh intensity statistics using a phase-only spatial light modulator. By introducing high order correlations to the input light fields we redistribute the intensity among the speckle…

Optics · Physics 2017-04-17 Yaron Bromberg , Hui Cao

Random lasers with low spatial coherence have important potential applications in high quality imaging and displaying. Here, a random laser with tunable angular spectra is proposed and fabricated through directly coupling an asymmetric…

Optics · Physics 2021-10-08 Huihui Shen , Yaoxing Bian , Junyan Li , Weinian Liu , Hanyi Xue , Zhaona Wang

Current optical manipulation techniques rely on carefully engineered setups and samples. Although similar conditions are routinely met in research laboratories, it is still a challenge to manipulate microparticles when the environment is…

The photoalignment technique for liquid crystal (LC) device fabrication, despite being a well-established method, remains of significant relevance because of its broad applicability. Among its applications, one of particular interest is the…

We consider the use of digital signal processing to reconstruct continuous reflectance spectra using a small finite set of randomly illuminated light emitting diodes (LEDs). We simulate the use of LEDs having identical spectral distance and…

Optics · Physics 2025-10-29 John C. Howell , Pieter H. Neethling , Tjaart P. J. Kruger

Random light fields -- commonly known as speckles -- demonstrate Rayleigh intensity statistics and only possess local correlations: which occur within the individual speckle grains. In this work, we develop an experimental method for…

Optics · Physics 2019-11-15 Nicholas Bender , Hasan Yılmaz , Yaron Bromberg , Hui Cao

We introduce a novel method to design and implement a tunable dynamical tissue phantom for laser speckle-based in-vivo blood flow imaging. This approach relies on Stochastic Differential Equations (SDE) to control a piezoelectric actuator…

Medical Physics · Physics 2024-04-24 Soumyajit Sarkar , K. Murali , Hari M. Varma

Structured light is a key component of many modern applications, ranging from superresolution microscopy to imaging, sensing, and quantum information processing. As the utilization of these powerful tools continues to spread, the demand for…

Spatially varying spectral modulation can be implemented using a liquid crystal spatial light modulator (SLM) since it provides an array of liquid crystal cells, each of which can be purposed to act as a programmable spectral filter array.…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Vishwanath Saragadam , Vijay Rengarajan , Ryuichi Tadano , Tuo Zhuang , Hideki Oyaizu , Jun Murayama , Aswin C. Sankaranarayanan

A single-pixel digital holography system with phase-encoded illumination using a digital micromirror device (DMD) as a spatial light modulator (SLM) is presented. The enhanced switching rate of DMDs, far exceeding the stringent frame-rate…

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