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Tunable dynamical tissue phantom for laser speckle imaging

Medical Physics 2024-04-24 v1

Abstract

We introduce a novel method to design and implement a tunable dynamical tissue phantom for laser speckle-based in-vivo blood flow imaging. This approach relies on Stochastic Differential Equations (SDE) to control a piezoelectric actuator which, upon illuminated with a laser source, generates speckles of pre-defined probability density function and auto-correlation. The validation experiments show that the phantom can generate dynamic speckles that closely replicate both surfaces as well as deep tissue blood flow for a reasonably wide range and accuracy.

Cite

@article{arxiv.2404.14577,
  title  = {Tunable dynamical tissue phantom for laser speckle imaging},
  author = {Soumyajit Sarkar and K. Murali and Hari M. Varma},
  journal= {arXiv preprint arXiv:2404.14577},
  year   = {2024}
}
R2 v1 2026-06-28T16:02:54.696Z