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We present an intensity speckle simulation algorithm based on stochastic differential equations. Intensity speckles are generated with a negative exponential distribution and an exponential auto-correlation decay. The mean of the…

Medical Physics · Physics 2021-07-19 Murali k , Hari M Varma

Dynamic speckle imaging, typically used in laser-illuminated surface diagnostics, has proven valuable for assessing biological activity. In this work, we demonstrate its feasibility in an endoscopic context using a disposable bronchoscope.…

Instrumentation and Detectors · Physics 2025-05-01 Aurélien plyer , Elise Colin , Enrique Garcia-Caurel

Speckled illumination enhances widefield fluorescence microscopy by enabling optical sectioning and super resolution. In random illumination microscopy, sequences of speckled illumination patterns are used to excite fluorescent samples and…

Photoacoustic tomography (PAT) is intrinsically sensitive to blood oxygen saturation (sO2) in vivo. However, making accurate sO2 measurements without knowledge of tissue- and instrumentation-related correction factors is extremely…

Medical Physics · Physics 2019-12-17 Marcel Gehrung , Sarah Bohndiek , Joanna Brunker

We experimentally generate three-dimensional speckles with customized intensity statistics. By modulating the phase front of a laser beam, far-field speckle patterns maintain the designed intensity probability density function while…

Optics · Physics 2023-03-15 SeungYun Han , Nicholas Bender , Hui Cao

This paper proposes the design of decision models based on Computational Intelligence techniques applied to image sequences of dynamic laser speckle. These models aim to identify image regions of biological specimens illuminated by a…

Structured illumination microscopy (SIM) reconstructs a super-resolved image from multiple raw images captured with different illumination patterns; hence, acquisition speed is limited, making it unsuitable for dynamic scenes. We propose a…

Optics · Physics 2025-06-17 Ruiming Cao , Fanglin Linda Liu , Li-Hao Yeh , Laura Waller

Optical speckle patterns have been widely used for illumination in computational imaging, optical sectioning microscopy, and super-resolution imaging. However, commonly used speckles satisfy Rayleigh statistics, which are not ideal for…

Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Significance: Optical imaging of blood oxygenation (sO$_2$) can be achieved based on the differential absorption spectra of oxy- and deoxy-haemoglobin. A key challenge in realising clinical validation of the sO$_2$ biomarkers is the absence…

Random lasers with low spatial coherence have important potential applications in high quality imaging and displaying. Here, a random laser with tunable angular spectra is proposed and fabricated through directly coupling an asymmetric…

Optics · Physics 2021-10-08 Huihui Shen , Yaoxing Bian , Junyan Li , Weinian Liu , Hanyi Xue , Zhaona Wang

We develop a general method for customizing the intensity statistics of speckle patterns on a target plane. By judiciously modulating the phase-front of a monochromatic laser beam, we experimentally generate speckle patterns with…

Optics · Physics 2019-03-12 Nicholas Bender , Hasan Yilmaz , Yaron Bromberg , Hui Cao

We study how stochastic differential equation (SDE) based ideas can inspire new modifications to existing algorithms for a set of problems in computer vision. Loosely speaking, our formulation is related to both explicit and implicit…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Zihang Meng , Vikas Singh , Sathya N. Ravi

Random light fields -- commonly known as speckles -- demonstrate Rayleigh intensity statistics and only possess local correlations: which occur within the individual speckle grains. In this work, we develop an experimental method for…

Optics · Physics 2019-11-15 Nicholas Bender , Hasan Yılmaz , Yaron Bromberg , Hui Cao

The characterization of dynamic phenomena using laser speckle has been studied in several applications and many descriptors have been developed to analyze the resulting images. In this work we compare the performance of a set of dynamic…

Objective: For real-time markerless tumour tracking in stereotactic lung radiotherapy, we propose a different approach which uses patient-specific deep learning (DL) using a personalized data generation strategy, avoiding the need for…

Medical Physics · Physics 2020-03-03 Wataru Takahashi , Shota Oshikawa , Shinichiro Mori

A bowtie is a filter used to shape an x-ray beam and equalize its flux reaching different detector channels. For development of spectral CT with energy-discriminative photon-counting (EDPC) detectors, here we propose and evaluate a dynamic…

Medical Physics · Physics 2013-04-30 Fenglin Liu , Ge Wang , Wenxiang Cong , Scott Hsieh , Norbert Pelc

Time-resolved photoluminescence (PL) is commonly used to track dynamics in a broad range of materials. Thus, the search for simplification of the acquisition of PL kinetics attracts continuous attention. This paper presents a new robust and…

Instrumentation and Detectors · Physics 2020-04-22 Jiri Junek , Lukas Ondic , Karel Zidek

Conventional frame-based camera is not able to meet the demand of rapid reaction for real-time applications, while the emerging dynamic vision sensor (DVS) can realize high speed capturing for moving objects. However, to achieve visual…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Lin Zhu , Siwei Dong , Tiejun Huang , Yonghong Tian

Optical techniques for spatiotemporal control can produce laser pulses with custom amplitude, phase, or polarization structure. In nonlinear optics and plasma physics, the use of structured pulses typically follows a forward design…

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