Related papers: Controlled release from polyurethane films: drug r…
We have developed a microfluidic tool to measure the diffusion coefficient $D$ of solutes in an aqueous solution, by following the temporal relaxation of an initially steep concentration gradient in a microchannel. Our chip exploits…
A flexible sheet in uniform parallel flow is studied in order to quantify its fluid dynamic drag and fluid-elastic stability characteristics. An experimental campaign is undertaken that involves a cantilevered sheet in air flow…
We use event driven simulations to analyze glassy dynamics as a function of density and energy dissipation in a two-dimensional bidisperse granular fluid under stationary conditions. Clear signatures of a glass transition are identified,…
In this paper, we study experimentally and theoretically the dynamics of liquid plugs in rectangular microchannels for both unidirectional and cyclic pressure forcing. In both cases, it is shown that the transition between quasi-static and…
Valveless pumping assists in fluid transport in various organisms and engineering systems. In a previous work, to study the actuator impact effects on valveless pumping, we constructed a piecewise-linear lumped-parameter model for a…
A key step in the development of a new drug is the design of drug-excipient complexes that lead to an optimal drug release kinetics. Computational chemistry, specifically enhanced sampling molecular dynamics methods, can play a key role in…
Rheo-optical measurements on Polyemethyl methacrylate (PMMA) and 4-Butoxycarbonylmethylurethane (4-BCMU) show that these synthetic random coil polymer chains compress in Couette flow at semi-dilute concentrations. All previous models of…
Releasing capsules are widely employed in biomedical applications as smart carriers of therapeutic agents, including drugs and bioactive compounds. Such delivery vehicles typically consist of a loaded core, enclosed by one or multiple…
Polymer stretching in random smooth flows is investigated within the framework of the FENE dumbbell model. The advecting flow is Gaussian and short-correlated in time. The stationary probability density function of polymer extension is…
We show that simulations of polymer rheology at a fluctuating mesoscopic scale and at the macroscopic scale where flow instabilities occur can be achieved at the same time with dissipative particle dynamics (DPD) technique.} We model the…
Thin liquid films are central to everyday life. They are ubiquitous in modern technology (pharmaceuticals, coatings), consumer products (foams, emulsions) and also serve vital biological functions (tear film of the eye, pulmonary…
We theoretically investigate Coulomb drag in a system of two parallel monolayers of graphene. Using a Boltzmann equation approach we study a variety of limits ranging from the non-degenerate interaction dominated limit close to charge…
Pulse-modulated feedback is utilized in drug dosing to mimic sustained over a longer period of time manual discrete dose administration, the latter is in contrast with continuous drug infusion. The intermittent mode of dosing calls for a…
The oral route is the most common choice for drug administration because of convenience, low cost, and high patient compliance, but is also a complex route. The rate of dissolution and gastric emptying of the dissolved active pharmaceutical…
Plasma treatment of polymer films results in their electrical charging, which in turn gives rise to an increase in their surface energy. The process results in pronounced hydrophilization of the polymer surfaces. A phenomenological theory…
The influence of structural constraints on the relaxation dynamics of three polyurea networks with varying degree of crosslinking, has been studied by means of a thorough analysis of broadband dielectric spectroscopy measurements. Two…
The surface morphologies of poly(chloro-p-xylylene) films were measured using atomic force microscopy and analyzed within the frame work of the dynamic scaling theory. The evolution of polymer films grown with fixed experimental parameters…
Airway clearance by coughing is a key mechanism for mucus transport, particularly in obstructive lung diseases associated with altered mucus rheology. We investigate the dynamics of a viscoplastic liquid film driven by flow in a turbulent…
Following our first report (A. Groisman and V. Steinberg, $\sl Nature$ $\bf 405$, 53 (2000)) we present an extended account of experimental observations of elasticity induced turbulence in three different systems: a swirling flow between…
Droplet velocities used in impact studies were investigated using high-speed photography. It was determined that droplets do not reach terminal velocity before a typical impact, raising the question of how to predict impact velocity. This…