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One of the promising frontiers of bioengineering is the controlled release of a therapeuticdrug from a vehicle across the skin (transdermal drug delivery). In order to study the complete process, a two-phase mathematical model describing…

Quantitative Methods · Quantitative Biology 2016-01-15 Giuseppe Pontrelli , Filippo de Monte

We study the rheology of a suspension of soft deformable droplets subjected to a pressure-driven flow. Through computer simulations, we measure the apparent viscosity as a function of droplet concentration and pressure gradient, and provide…

Soft Condensed Matter · Physics 2017-11-22 M. Foglino , A. N. Morozov , O. Henrich , D. Marenduzzo

We study droplet dynamics and breakup in generic time-dependent flows via a multicomponent Lattice Boltzmann algorithm, with emphasis on flow start up conditions. We first study droplet breakup in a confined oscillatory shear flow via two…

Fluid Dynamics · Physics 2020-03-18 Felix Milan , Luca Biferale , Mauro Sbragaglia , Federico Toschi

The presence of dispersed-phase droplets can result in a notable increase in the system's drag. However, our understanding of the mechanism underlying this phenomenon remains limited. In this study, we use three-dimensional direct numerical…

Fluid Dynamics · Physics 2024-11-21 Jinghong Su , Yi-bao Zhang , Cheng Wang , Lei Yi , Fan Xu , Yaning Fan , Junwu Wang , Chao Sun

We present the high pressure dielectric spectroscopy (up to 4.2 GPa) and ultrasonic study (up to 1.7 GPa) of liquid and glassy propylene carbonate (PC). Both of the methods provide complementary pictures of the glass transition in PC under…

Soft Condensed Matter · Physics 2013-05-17 M. V. Kondrin , E. L. Gromnitskaya , A. A. Pronin , A. G. Lyapin , V. V. Brazhkin , A. A. Volkov

The structural arrest of a polymeric suspension might be driven by an increase of the cross--linker concentration, that drives the gel transition, as well as by an increase of the polymer density, that induces a glass transition. These…

Statistical Mechanics · Physics 2014-06-20 Nagi Khalil , Antonio Coniglio , Antonio de Candia , Annalisa Fierro , Massimo Pica Ciamarra

The glass transition temperature and relaxation dynamics of the segmental motions of thin films of polystyrene labeled with a dye, 4-[N-ethyl-N-(hydroxyethyl)]amino-4-nitraozobenzene (Disperse Red 1, DR1) are investigated using dielectric…

Soft Condensed Matter · Physics 2009-11-13 Rodney D. Priestley , Linda J. Broadbelt , John M. Torkelson , Koji Fukao

Probing the fluid dynamics of thin films is an excellent tool to study the solid/liquid boundary condition. There is no need for external stimulation or pumping of the liquid due to the fact that the dewetting process, an internal…

Soft Condensed Matter · Physics 2009-09-11 O. Baeumchen , K. Jacobs

In gravel-bed rivers, bedload transport exhibits considerable variability in time and space. Recently, stochastic bedload transport theories have been developed to address the mechanisms and effects of bedload transport fluctuations.…

Fluid Dynamics · Physics 2016-12-21 J. Heyman , P. Bohorquez , C. Ancey

Active emulsions can spontaneously form self-propelled droplets or phoretic micropumps. It has been predicted that the interaction with their self-generated chemical fields can lead to multistable higher-order flows and chemodynamic…

Depending on their mechanism of self-propulsion, active particles can exhibit a time-dependent, often periodic, propulsion velocity. The precise propulsion velocity profile determines their mean square displacement and their effective…

Soft Condensed Matter · Physics 2024-05-06 Arnau Jurado Romero , Carles Calero , Rossend Rey

The velocity relaxation of an impulsively forced spherical particle in a fluid confined by two parallel plane walls is studied using a direct numerical simulation approach. During the relaxation process, the momentum of the particle is…

Fluid Dynamics · Physics 2015-06-15 Rei Tatsumi , Ryoichi Yamamoto

Very high frequency (VHF) driven capacitive discharges are now being increasingly adopted for plasma-based materials processing due to their high processing rates and lower substrate damage. Past studies related to complex plasma dynamics…

Plasma Physics · Physics 2020-12-30 Sarveshwar Sharma , Nishant Sirse , Animesh Kuley , Abhijit Sen , Miles M Turner

A FLIP device gives cross-sectional area along the length of the esophagus and one pressure measurement, both as a function of time. Deducing mechanical properties of the esophagus including wall material properties, contraction strength,…

One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…

Applications · Statistics 2018-12-04 Luis F. Campos , Mark E. Glickman , Kristen B. Hunter

Experimental studies of systems containing active proteins that undergo conformational changes driven by catalytic chemical reactions have shown that the diffusion coefficients of passive tracer particles and active molecules are larger…

Soft Condensed Matter · Physics 2017-02-27 Matthew Dennison , Raymond Kapral , Holger Stark

The variation of blood flow characteristics caused by the probe pressure during noninvasive studies is of particular interest within the context of fundamental and applied research. It has been shown previously that the weak local pressure…

A simple stochastic model which describes microtubule dynamics and explicitly takes into account the relevant biochemical processes is presented. The model incorporates binding and unbinding of monomers and random phosphate release inside…

Statistical Mechanics · Physics 2015-05-27 Ranjith Padinhateeri , Anatoly B. Kolomeisky , David Lacoste

We experimentally demonstrate that the flow rate of granular material through an aperture is controlled by the exit velocity imposed to the particles and not by the pressure at the base, contrary to what is often assumed in previous works.…

A stochastic model for the dynamics of enzymatic catalysis in explicit, effective solvents under physiological conditions is presented. Analytically-computed first passage time densities of a diffusing particle in a spherical shell with…

Biomolecules · Quantitative Biology 2015-06-04 Jeremy Schofield , Paul Inder , Raymond Kapral