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Modern histopathology relies on the microscopic examination of thin tissue sections stained with histochemical techniques, typically using brightfield or fluorescence microscopy. However, the staining of samples can permanently alter their…

While diffusion models have made remarkable progress in image generation, their outputs can still appear unrealistic and lack fine details, especially when using fewer number of neural function evaluations (NFEs) or lower guidance scales.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Seyedmorteza Sadat , Farnood Salehi , Romann M. Weber

Integrated Gradients (IG) is a widely adopted feature attribution method that satisfies desirable axiomatic properties. However, the choice of integration path significantly affects the quality of attributions, and the standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Soyeon Kim , Seongwoo Lim , Kyowoon Lee , Jaesik Choi

Information-theoretic image quality assessment (IQA) models such as Visual Information Fidelity (VIF) and Spatio-temporal Reduced Reference Entropic Differences (ST-RRED) have enjoyed great success by seamlessly integrating natural scene…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Abhinau K. Venkataramanan , Alan C. Bovik

Scene Graph Generation (SGG) suffers from a long-tailed distribution, where a few predicate classes dominate while many others are underrepresented, leading to biased models that underperform on rare relations. Unbiased-SGG methods address…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Runfeng Qu , Ole Hall , Pia K Bideau , Julie Ouerfelli-Ethier , Martin Rolfs , Klaus Obermayer , Olaf Hellwich

Virtual stain transfer is a promising area of research in Computational Pathology, which has a great potential to alleviate important limitations when applying deeplearningbased solutions such as lack of annotations and sensitivity to a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Jelica Vasiljević , Friedrich Feuerhake , Cédric Wemmert , Thomas Lampert

Hematoxylin and eosin (H&E)-stained slides are central to cancer diagnosis and monitoring, visualizing tissue architecture and cellular morphology. However, H&E lacks the molecular specificity needed to distinguish cell states and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

This paper studies stable learning methods for generative models that enable high-quality data generation. Noise injection is commonly used to stabilize learning. However, selecting a suitable noise distribution is challenging.…

Machine Learning · Statistics 2024-10-29 Yoshitaka Koike , Takumi Nakagawa , Hiroki Waida , Takafumi Kanamori

Learner performance data collected by Intelligent Tutoring Systems (ITSs), such as responses to questions, is essential for modeling and predicting learners' knowledge states. However, missing responses due to skips or incomplete attempts…

Deep neural networks have produced significant progress among machine learning models in terms of accuracy and functionality, but their inner workings are still largely unknown. Attribution methods seek to shine a light on these "black box"…

Machine Learning · Computer Science 2023-06-27 Daniel Lundstrom , Meisam Razaviyayn

Integrated Gradients (IG), a widely used axiomatic path-based attribution method, assigns importance scores to input features by integrating model gradients along a straight path from a baseline to the input. While effective in some cases,…

Machine Learning · Computer Science 2026-02-27 Sina Salek , Joseph Enguehard

Despite being trained on balanced datasets, existing AI-generated image detectors often exhibit systematic bias at test time, frequently misclassifying fake images as real. We hypothesize that this behavior stems from distributional shift…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Muli Yang , Gabriel James Goenawan , Henan Wang , Huaiyuan Qin , Chenghao Xu , Yanhua Yang , Fen Fang , Ying Sun , Joo-Hwee Lim , Hongyuan Zhu

Image inpainting techniques have shown promising improvement with the assistance of generative adversarial networks (GANs) recently. However, most of them often suffered from completed results with unreasonable structure or blurriness. To…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Zheng Hui , Jie Li , Xiumei Wang , Xinbo Gao

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Junhyeok Lee , Han Jang , Heeseong Eum , Joon Jang , Kyu Sung Choi

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Generative adversarial networks (GANs) have given us a great tool to fit implicit generative models to data. Implicit distributions are ones we can sample from easily, and take derivatives of samples with respect to model parameters. These…

Machine Learning · Statistics 2017-02-28 Ferenc Huszár

Computer vision is hard because of a large variability in lighting, shape, and texture; in addition the image signal is non-additive due to occlusion. Generative models promised to account for this variability by accurately modelling the…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Varun Jampani , Sebastian Nowozin , Matthew Loper , Peter V. Gehler

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Generative Adversarial Networks (GANs) advance face synthesis through learning the underlying distribution of observed data. Despite the high-quality generated faces, some minority groups can be rarely generated from the trained models due…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Shuhan Tan , Yujun Shen , Bolei Zhou

Diffusion probabilistic models learn to remove noise added during training, generating novel data (e.g., images) from Gaussian noise through sequential denoising. However, conditioning the generative process on corrupted or masked images is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Sakshi Agarwal , Gabriel Hope , Jimin Heo , Erik B. Sudderth