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Artificial Intelligence (AI) systems are transforming critical sectors such as healthcare, finance, and transportation, enhancing operational efficiency and decision-making processes. However, their deployment in high-stakes domains has…

Computers and Society · Computer Science 2025-08-01 Diego Russo , Gian Marco Orlando , Valerio La Gatta , Vincenzo Moscato

The lack of interpretability in the field of medical image analysis has significant ethical and legal implications. Existing interpretable methods in this domain encounter several challenges, including dependency on specific models,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Lijie Hu , Songning Lai , Wenshuo Chen , Hongru Xiao , Hongbin Lin , Lu Yu , Jingfeng Zhang , Di Wang

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

As large language models (LLMs) become integrated into everyday and high-stakes decision-making, they inherit the ambiguity and biases of human language. While they produce fluent and coherent outputs, they rely on statistical pattern…

Artificial Intelligence · Computer Science 2026-04-17 Rikard Rosenbacke , Carl Rosenbacke , Victor Rosenbacke , Martin McKee

To improve the trustworthiness of an AI model, finding consistent, understandable representations of its inference process is essential. This understanding is particularly important in high-stakes operations such as weather forecasting,…

Artificial Intelligence · Computer Science 2025-04-02 Soyeon Kim , Junho Choi , Subeen Lee , Jaesik Choi

Public health reasoning requires population level inference grounded in scientific evidence, expert consensus, and safety constraints. However, it remains underexplored as a structured machine learning problem with limited supervised…

Computation and Language · Computer Science 2026-05-27 Zhaokun Yan , Shan Xu , Wuzheng Dong , Zhaohan Liu , Lijie Feng , Chengxiao Dai , Chen Tianqi , Binfan Liu , Yunpu Ma , Wenting Wei , Yingting Li , Yi Zhang , Tongning Wu

Adaptive medical AI models often face performance drops in dynamic clinical environments due to data drift. We propose an autonomous continuous monitoring and data integration framework that maintains robust performance over time. Focusing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Mohammad Daouk , Jan Ulrich Becker , Neeraja Kambham , Anthony Chang , Chandra Mohan , Hien Van Nguyen

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological…

Computation and Language · Computer Science 2025-10-14 Wenqing Zhang , Trang Nguyen , Elizabeth A. Stuart , Yiqun T. Chen

Trustworthiness and transparency are essential for the clinical adoption of artificial intelligence (AI) in healthcare and biomedical research. Recent deep research systems aim to accelerate evidence-grounded scientific discovery by…

The regulatory approval and broad clinical deployment of medical AI have been hampered by the perception that deep learning models fail in unpredictable and possibly catastrophic ways. A lack of statistically rigorous uncertainty…

Machine Learning · Computer Science 2022-07-07 Charles Lu , Anastasios N. Angelopoulos , Stuart Pomerantz

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

Artificial Intelligence · Computer Science 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nicklas Neu , Thomas Ebner , Jasmin Primus , Bernhard Schenkenfelder , Raphael Zefferer , Mathias Brunbauer , Florian Kromp

Medicine is rife with high-stakes uncertainty. Doctors routinely make clinical judgments and decisions that juggle many fundamental unknowns, like predictions about what might be causing a patients' symptoms or decisions about what…

With the growing use of language models (LMs) in clinical environments, there is an immediate need to evaluate the accuracy and safety of LM-generated medical text. Currently, such evaluation relies solely on manual physician review.…

Transparency in Machine Learning (ML), attempts to reveal the working mechanisms of complex models. Transparent ML promises to advance human factors engineering goals of human-centered AI in the target users. From a human-centered design…

Human-Computer Interaction · Computer Science 2022-10-03 Haomin Chen , Catalina Gomez , Chien-Ming Huang , Mathias Unberath

Explainable Artificial Intelligence (XAI) has become critical in enhancing the transparency and trustworthiness of AI systems, especially as these systems are increasingly deployed in high-stakes domains such as healthcare and finance.…

Symbolic Computation · Computer Science 2024-08-13 Shengxin Hong , Xiuyi Fan

The ability to translate diverse patterns of inputs into structured patterns of behavior has been thought to rest on both humans' and machines' ability to learn robust representations of relevant concepts. The rapid advancement of…

Artificial Intelligence · Computer Science 2025-10-02 Zach Studdiford , Timothy T. Rogers , Kushin Mukherjee , Siddharth Suresh

Large Language Models (LLMs) are increasingly employed in software engineering tasks such as requirements elicitation, design, and evaluation, raising critical questions regarding their alignment with human judgments on responsible AI…

Software Engineering · Computer Science 2025-11-07 Asma Yamani , Malak Baslyman , Moataz Ahmed

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger
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