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Wearable devices record physiological and behavioral signals that can improve health predictions. While foundation models are increasingly used for such predictions, they have been primarily applied to low-level sensor data, despite…

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier

Artificial intelligence foundation models are increasingly deployed for prostate cancer Gleason grading, where GP3/GP4 distinction directly impacts treatment decisions. However, these models may achieve high validation accuracy by learning…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Joshua L. Ebbert , Dennis Della Corte

Mitotic figures are classified into typical and atypical variants, with atypical counts correlating strongly with tumor aggressiveness. Accurate differentiation is therefore essential for patient prognostication and resource allocation, yet…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Mieko Ochi , Bae Yuan

Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide…

NLP models often rely on superficial cues known as dataset biases to achieve impressive performance, and can fail on examples where these biases do not hold. Recent work sought to develop robust, unbiased models by filtering biased examples…

Computation and Language · Computer Science 2023-05-31 Yuval Reif , Roy Schwartz

Foundation models refer to artificial intelligence (AI) models that are trained on massive amounts of data and demonstrate broad generalizability across various tasks with high accuracy. These models offer versatile, one-for-many or…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Rina Bao , Erfan Darzi , Sheng He , Chuan-Heng Hsiao , Mohammad Arafat Hussain , Jingpeng Li , Atle Bjornerud , Ellen Grant , Yangming Ou

The development of foundation models for brain MRI depends critically on the scale, diversity, and consistency of available data, yet systematic assessments of these factors remain scarce. In this study, we analyze 54 publicly accessible…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Minh Sao Khue Luu , Margaret V. Benedichuk , Ekaterina I. Roppert , Roman M. Kenzhin , Bair N. Tuchinov

Deep learning based methods for image reconstruction are state-of-the-art for a variety of imaging tasks. However, neural networks often perform worse if the training data differs significantly from the data they are applied to. For…

Image and Video Processing · Electrical Eng. & Systems 2024-08-08 Kang Lin , Reinhard Heckel

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Reliable predictions from systems biology models require knowing whether parameters can be estimated from available data, and with what certainty. Identifiability analysis reveals whether parameters are learnable in principle (structural…

The development of deep learning algorithms has extensively empowered humanity's task automatization capacity. However, the huge improvement in the performance of these models is highly correlated with their increasing level of complexity,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Eduarda Caldeira , Pedro C. Neto , Marco Huber , Naser Damer , Ana F. Sequeira

Causal structure learning refers to a process of identifying causal structures from observational data, and it can have multiple applications in biomedicine and health care. This paper provides a practical review and tutorial on scalable…

Machine Learning · Computer Science 2023-01-20 Pulakesh Upadhyaya , Kai Zhang , Can Li , Xiaoqian Jiang , Yejin Kim

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

To develop a preliminary understanding towards Graph Foundation Models, we study the extent to which pretrained Graph Neural Networks can be applied across datasets, an effort requiring to be agnostic to dataset-specific features and their…

Foundation models are deep neural networks (such as GPT-5, Gemini~3, and Opus~4) trained on large datasets that can perform diverse downstream tasks -- text and code generation, question answering, summarization, image classification, and…

Machine Learning · Computer Science 2026-05-01 Logan G Wright , Tianyu Wang , Tatsuhiro Onodera , Peter L. McMahon

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu
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