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Target Safety Assessment (TSA) requires systematic integration of heterogeneous evidence, including genetic, transcriptomic, target homology, pharmacological, and clinical data, to evaluate potential safety liabilities of therapeutic…

Computation and Language · Computer Science 2026-05-11 Xiaochen Zheng , Zhiwen Jiang , Melanie Guerard , Klas Hatje , Tatyana Doktorova

Multimodal large language models (MLLMs) have demonstrated strong capabilities in visual understanding, yet they remain limited in complex, multi-step reasoning that requires deep searching and integrating visual evidence with external…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Xiangyu Peng , Can Qin , An Yan , Xinyi Yang , Zeyuan Chen , Ran Xu , Chien-Sheng Wu

The rise of generative and autonomous agents marks a fundamental shift in computing, demanding a rethinking of how humans collaborate with probabilistic, partially autonomous systems. We present the Human-AI-Experience (HAX) framework, a…

Human-Computer Interaction · Computer Science 2025-12-16 Marc Scibelli , Krystelle Gonzalez Papaux , Julia Valenti , Srishti Kush

Does human-AI assistance unfold in the same way as human-human assistance? This research explores what can be learned from the expertise of blind individuals and sighted volunteers to inform the design of multimodal voice agents and address…

Human-Computer Interaction · Computer Science 2026-02-06 Damien Rudaz , Barbara Nino Carreras , Sara Merlino , Brian L. Due , Barry Brown

AI agents are promising for high-stakes enterprise workflows, but dependable deployment remains limited because tool-use failures are difficult to diagnose and control. Agents may skip required tool calls, invoke tools unnecessarily, or…

Artificial Intelligence · Computer Science 2026-05-22 Hariom Tatsat , Ariye Shater

Artificial intelligence (AI) is increasingly permeating healthcare, from physician assistants to consumer applications. Since AI algorithm's opacity challenges human interaction, explainable AI (XAI) addresses this by providing AI…

Explainable AI (XAI) holds the promise of advancing the implementation and adoption of AI-based tools in practice, especially in high-stakes environments like healthcare. However, most of the current research lacks input from end users, and…

Machine Learning · Computer Science 2025-08-06 T. E. Röber , R. Goedhart , S. İ. Birbil

Multi-modal representation methods have achieved advanced performance in medical applications by extracting more robust features from multi-domain data. However, existing methods usually need to train additional branches for downstream…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Weijian Huang , Hao Yang , Cheng Li , Mingtong Dai , Rui Yang , Shanshan Wang

Human-AI collaboration to identify and correct perceptual errors in chest radiographs has not been previously explored. This study aimed to develop a collaborative AI system, CoRaX, which integrates eye gaze data and radiology reports to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Akash Awasthi , Ngan Le , Zhigang Deng , Carol C. Wu , Hien Van Nguyen

Recent progress in multimodal graph neural networks has demonstrated that augmenting atomic XYZ geometries with textual chemical descriptors can enhance predictive accuracy across a range of electronic and thermodynamic properties. However,…

Multiagent Systems · Computer Science 2025-06-27 Can Polat , Mehmet Tuncel , Mustafa Kurban , Erchin Serpedin , Hasan Kurban

Existing AI-generated text detection methods heavily depend on large annotated datasets and external threshold tuning, restricting interpretability, adaptability, and zero-shot effectiveness. To address these limitations, we propose…

Computation and Language · Computer Science 2025-05-22 Jiatao Li , Mao Ye , Cheng Peng , Xunjian Yin , Xiaojun Wan

We examine the problem of explainable AI (xAI) and explore what delivering xAI means in practice, particularly in contexts that involve formal or informal and ad-hoc collaboration where agency and accountability in decision-making are…

Human-Computer Interaction · Computer Science 2020-10-06 Rob Procter , Mark Rouncefield , Peter Tolmie

Effective human-AI teaming heavily depends on swift trust, particularly in high-stakes scenarios such as emergency response, where timely and accurate decision-making is critical. In these time-sensitive and cognitively demanding settings,…

Artificial Intelligence · Computer Science 2025-07-30 Nishani Fernando , Bahareh Nakisa , Adnan Ahmad , Mohammad Naim Rastgoo

AI-assisted report generation offers the opportunity to reduce radiologists' workload stemming from expanded screening guidelines, complex cases and workforce shortages, while maintaining diagnostic accuracy. In addition to describing…

Modern human labor is characterized by specialization; we train for years and develop particular tools that allow us to perform well across a variety of tasks. In addition, AI agents have been specialized for domains such as software…

Computation and Language · Computer Science 2025-06-04 Aditya Bharat Soni , Boxuan Li , Xingyao Wang , Valerie Chen , Graham Neubig

Explainable Artificial Intelligence (XAI) is critical for ensuring trust and accountability, yet its development remains predominantly visual. For blind and low-vision (BLV) users, the lack of accessible explanations creates a fundamental…

Human-Computer Interaction · Computer Science 2026-05-05 Abu Noman Md Sakib , Protik Dey , Zijie Zhang , Taslima Akter

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

Computer-Using Agents (CUAs) aim to autonomously operate computer systems to complete real-world tasks. However, existing agentic systems remain difficult to scale and lag behind human performance. A key limitation is the absence of…

Multi-agent systems (MAS) are increasingly used in healthcare to support complex decision-making through collaboration among specialized agents. Because these systems act as collective decision-makers, they raise challenges for trust,…

Artificial Intelligence · Computer Science 2026-03-24 Truong Thanh Hung Nguyen , Hélène Fournier , Piper Jackson , Makoto Itoh , Shannon Freeman , Rene Richard , Hung Cao

Explainable Reinforcement Learning (XRL) has emerged as a promising approach in improving the transparency of Reinforcement Learning (RL) agents. However, there remains a gap between complex RL policies and domain experts, due to the…

Artificial Intelligence · Computer Science 2025-09-09 Haechang Kim , Hao Chen , Can Li , Jong Min Lee
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