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Related papers: Novel Asymmetrical High-Resolution and High-Sensit…

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A NEMA performance evaluation was conducted on the new General Electric (GE) digital Omni Legend PET-CT system with 32-cm extended field-of-view. This study marks the introduction of the first-ever commercially available clinical digital…

Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…

Medical Physics · Physics 2021-09-29 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Hiroyuki Ohba , Ryosuke Ota , Etsuji Yoshikawa , Yasuomi Ouchi

Crystal arrays made of LSO and LuAP crystals 2x2x10 mm pixels were manufactured for evaluation of detector with depth-of-interaction (DOI) determination capability intended for small animal positron emission tomograph. Position-sensitive…

Instrumentation and Detectors · Physics 2007-05-23 A. Fedorov , A. Annenkov , A. Kholmetsky , M. Korzhik , P. Lecoq , A. Lobko , O. Missevitch , A. Tkatchov

High-resolution dense prediction enables many appealing real-world applications, such as computational photography, autonomous driving, etc. However, the vast computational cost makes deploying state-of-the-art high-resolution dense…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Han Cai , Junyan Li , Muyan Hu , Chuang Gan , Song Han

This work summarizes the design, construction, initial performance evaluation and pilot clinical results of the IMAS system, a long axial field of view (FOV), also known as total-body (TB-), positron emission tomography (PET) prototype…

Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ramy Hussein , David Shin , Moss Zhao , Jia Guo , Guido Davidzon , Michael Moseley , Greg Zaharchuk

Intraoperative optical imaging is a localization technique for the functional areas of the human brain cortex during neurosurgical procedures. These areas can be assessed by monitoring cerebral hemodynamics and metabolism. A robust…

The Dynamic Cardiac SPECT (DC-SPECT) system is being developed at the Massachusetts General Hospital, featuring a static cardio focus asymmetrical geometry enabling simultaneous high resolution and high sensitivity imaging. Among 14 design…

Medical Physics · Physics 2023-01-02 Yuemeng Feng , William Worstell , Matthew Kupinski , Lars R Furenlid , Hamid Sabet

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

We formulate an optimization problem to estimate probability densities in the context of multidimensional problems that are sampled with uneven probability. It considers detector sensitivity as an heterogeneous density and takes advantage…

Machine Learning · Computer Science 2025-06-04 Aleix Boquet-Pujadas , Pol del Aguila Pla , Michael Unser

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

We aim to optimize the binary detection of Chronic Obstructive Pulmonary Disease (COPD) based on emphysema presence in the lung with convolutional neural networks (CNN) by exploring manually adjusted versus automated window-setting…

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

Medical Physics · Physics 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

A tightly focused pulsed laser can locally modify the crystal structure inside the bulk of a scintillator. The result is incorporation of so-called optical barriers with a refractive index (RI) different from that of the crystal bulk, that…

Medical Physics · Physics 2018-07-11 Lisa Bläckberg , Georges El Fakhri , Hamid Sabet

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

Automated fetal head segmentation in ultrasound images is critical for accurate biometric measurements in prenatal care. While existing deep learning approaches have achieved a reasonable performance, they struggle with issues like low…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Ammar Bhilwarawala , Mainak Bandyopadhyay

Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…

Medical Physics · Physics 2023-08-08 Fumio Hashimoto , Yuya Onishi , Kibo Ote , Hideaki Tashima , Taiga Yamaya

Depth electrodes used in stereoelectroencephalography (sEEG) and deep-brain stimulation (DBS) are essential tools for neural recording and stimulation. Traditional designs have limited spatial resolution, typically 8 to 16 cylindrical…

Purpose: The physical properties of yttrium-90 (90Y) allow for imaging with positron emission tomography/computed tomography (PET/CT). The increased sensitivity of long axial field-of-view (LAFOV) PET/CT scanners possibly allows to overcome…