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Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

Quantitative Methods · Quantitative Biology 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

Mechanistic interpretability improves the safety, reliability, and robustness of large AI models. This study examined individual attention heads in vision transformers (ViTs) fine tuned on distorted 2D spectrogram images containing non…

Machine Learning · Computer Science 2025-03-25 Nooshin Bahador

Although interpretable prototype networks have improved the transparency of deep learning image classification, the need for multiple prototypes in collaborative decision-making increases cognitive complexity and hinders user understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Yitao Peng , Lianghua He , Hongzhou Chen

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Multimodal Large Language Models (MLLMs) have shown promise in visual-textual reasoning, with Multimodal Chain-of-Thought (MCoT) prompting significantly enhancing interpretability. However, existing MCoT methods rely on rationale-rich…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Yiwen Jiang , Deval Mehta , Siyuan Yan , Yaling Shen , Zimu Wang , Zongyuan Ge

Physics-informed neural networks (PINNs) provide a promising framework for solving inverse problems governed by partial differential equations (PDEs) by integrating observational data and physical constraints in a unified optimization…

Machine Learning · Computer Science 2026-04-07 Yongsheng Chen , Yong Chen , Wei Guo , Xinghui Zhong

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Large Language Models (LLMs) have experienced a rapid rise in AI, changing a wide range of applications with their advanced capabilities. As these models become increasingly integral to decision-making, the need for thorough…

Machine Learning · Computer Science 2024-01-09 Jatin Nainani

Solving Partial Differential Equations (PDEs) is fundamental to numerous scientific and engineering disciplines. A common challenge arises from solving the PDE families, which are characterized by sharing an identical mathematical structure…

Artificial Intelligence · Computer Science 2026-02-13 Yipeng Huang , Dejun Xu , Zexin Lin , Zhenzhong Wang , Min Jiang

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Despite the impressive advancements achieved using deep-learning for functional brain activity analysis, the heterogeneity of functional patterns and scarcity of imaging data still pose challenges in tasks such as prediction of future onset…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Wenhui Cui , Haleh Akrami , Ganning Zhao , Anand A. Joshi , Richard M. Leahy

Machine learning is used more and more often for sensitive applications, sometimes replacing humans in critical decision-making processes. As such, interpretability of these algorithms is a pressing need. One popular algorithm to provide…

Machine Learning · Computer Science 2020-01-14 Damien Garreau , Ulrike von Luxburg

Deep neural networks have achieved remarkable performance in various text-based tasks but often lack interpretability, making them less suitable for applications where transparency is critical. To address this, we propose ProtoLens, a novel…

Computation and Language · Computer Science 2024-10-25 Bowen Wei , Ziwei Zhu

Medical imaging and multi-modal clinical settings often face the challange of missing modality in their diagnostic pipelines. Existing imputation methods either lack representational capacity or are computationally expensive. We propose…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Afifa Khaled , Ebrahim Hamid Sumiea

As deep neural network (DNN) models are growing exponentially in size, their deployment on resource-constrained edge platforms is becoming increasingly challenging. In-memory-computing (IMC) with non-volatile memories (NVMs) has emerged as…

Emerging Technologies · Computer Science 2026-04-07 Imtiaz Ahmed , Sumeet Kumar Gupta

Accurate and automatic segmentation of brain tumors in multi-parametric magnetic resonance imaging (mpMRI) is essential for quantitative measurements, which play an increasingly important role in clinical diagnosis and prognosis. The…

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

While physics-informed neural networks (PINNs) have become a popular deep learning framework for tackling forward and inverse problems governed by partial differential equations (PDEs), their performance is known to degrade when larger and…

Machine Learning · Computer Science 2024-02-13 Sifan Wang , Bowen Li , Yuhan Chen , Paris Perdikaris
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