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Initial residual stress is omnipresent in biological tissues and soft matter, and can affect growth-induced pattern selection significantly. Here we demonstrate this effect experimentally by letting soft tubes grow in the presence or…

Soft Condensed Matter · Physics 2020-09-11 Yangkun Du , Chaofeng Lü , Congshan Liu , Zilong Han , Jian Li , Weiqi Chen , Shaoxing Qua , Michel Destrade

The supramolecular assembly of lipids into bilayer membranes is essential for cellular structure and function. However, the impact of lipid structural variations such as acyl chain length, degree of unsaturation, and headgroup type on…

Soft Condensed Matter · Physics 2024-12-13 Sonam Phuntsho

The study of growth-induced surface wrinkling in constrained bilayers comprising a thin film attached to a thick substrate is a canonical model for understanding pattern formation in many biological systems. While the bilayer model has…

Soft Condensed Matter · Physics 2024-05-21 Jiajia Shen , Yibin Fu , Alberto Pirrera , Rainer M. J. Groh

Self-assembly into target structures is an efficient material design strategy. Combining analytical calculations and computational techniques of evolutionary and Monte Carlo types, we report about a remarkable structural variability of…

Soft Condensed Matter · Physics 2016-09-28 M. Antlanger , G. Kahl , M. Mazars , L. Samaj , E. Trizac

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

We present a theory for the damping of layer-by-layer growth oscillations in molecular beam epitaxy. The surface becomes rough on distances larger than a layer coherence length which is substantially larger than the diffusion length. The…

Statistical Mechanics · Physics 2009-10-30 H. Kallabis , L. Brendel , J. Krug , D. E. Wolf

Anisotropic collective patterns occur frequently in the morphogenesis of 2D biofilms. These patterns are often attributed to growth regulation mechanisms and differentiation based on gradients of diffusing nutrients and signalling…

Biological Physics · Physics 2017-10-11 Cameron Zachreson , Xinhui Yap , Erin S. Gloag , Raz Shimoni , Cynthia B. Whitchurch , Milos Toth

Shape-programmed sheets morph from one surface into another upon activation by stimuli such as illumination, and have attracted much interest for their potential engineering applications, especially in soft robotics. Complex shape changes…

Soft Condensed Matter · Physics 2024-10-17 Daniel Duffy , Itay Griniasty , John Biggins , Cyrus Mostajeran

We introduce a general theoretical framework to study the shape dynamics of actively growing and remodeling surfaces. Using this framework we develop a physical model for growing bacterial cell walls and study the interplay of cell shape…

Biological Physics · Physics 2016-04-08 Shiladitya Banerjee , Norbert F. Scherer , Aaron R. Dinner

Growth-induced instabilities are ubiquitous in biological systems and lead to diverse morphologies in the form of wrinkling, folding, and creasing. The current work focusses on the mechanics behind growth-induced wrinkling instabilities in…

Pattern Formation and Solitons · Physics 2022-06-28 Sumit Mehta , Gangadharan Raju , Prashant Saxena

How does growth encode form in developing organisms? Many different spatiotemporal growth profiles may sculpt tissues into the same target 3D shapes, but only specific growth patterns are observed in animal and plant development. In…

Soft Condensed Matter · Physics 2023-02-16 Dillon J. Cislo , Anastasios Pavlopoulos , Boris I. Shraiman

Surface tension governed by differential adhesion can drive fluid particle mixtures to sort into separate regions, i.e., demix. Does the same phenomenon occur in confluent biological tissues? We begin to answer this question for epithelial…

The sessile microbial communities known as biofilms exhibit varying architectures as environmental factors are varied, which for immersed biofilms includes the shear rate of the surrounding flow. Here we modify an established agent-based…

Biological Physics · Physics 2014-03-11 D. A. Head

During development, organisms acquire three-dimensional shapes with important physiological consequences. While the basic mechanisms underlying morphogenesis are known in eukaryotes, it is often difficult to manipulate them in vivo. To…

Tissue growth kinetics and interface dynamics depend on the properties of the tissue environment and cell-cell interactions. In cellular environments, substrate heterogeneity and geometry arise from a variety factors, such as the structure…

Soft Condensed Matter · Physics 2023-03-21 Mahmood Mazarei , Jan Astrom , Jan Westerlund , Mikko Karttunen

Giant unilamellar vesicles (GUVs) composed of as few as three lipid species can phase separate into small-scale lipid domains with stripes and dots patterns. These patterns have been experimentally characterized in terms of how their size…

Soft Condensed Matter · Physics 2025-05-21 Qiwei Yu , Andrej Košmrlj

Smooth and curved microstructural topologies found in nature - from soap films to trabecular bone - have inspired several mimetic design spaces for architected metamaterials and bio-scaffolds. However, the design approaches so far have been…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Yaqi Guo , Saurav Sharma , Siddhant Kumar

Soft and biological matter come in a variety of shapes and geometries. When soft surfaces that do not fit into each other due to a mismatch in Gaussian curvatures form an interface, beautiful geometry-induced patterns emerge. In this paper,…

Soft Condensed Matter · Physics 2024-04-05 Aashna Chawla , Deepak Kumar

We study the interplay between surface roughening and phase separation during the growth of binary films. Already in 1+1 dimension, we find a variety of different scaling behaviors depending on how the two phenomena are coupled. In the most…

Statistical Mechanics · Physics 2009-10-31 Barbara Drossel , Mehran Kardar

A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…

Biological Physics · Physics 2018-12-26 T. A. Engstrom , Teng Zhang , A. K. Lawton , A. L. Joyner , J. M. Schwarz