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Current machine learning has made great progress on computer vision and many other fields attributed to the large amount of high-quality training samples, while it does not work very well on genomic data analysis, since they are notoriously…

Machine Learning · Computer Science 2020-09-04 Ziyi Yang , Jun Shu , Yong Liang , Deyu Meng , Zongben Xu

The paper presents a systematic review of state-of-the-art approaches to identify patient cohorts using electronic health records. It gives a comprehensive overview of the most commonly de-tected phenotypes and its underlying data sets.…

Machine Learning · Statistics 2017-07-25 Norman Hiob , Stefan Lessmann

Electronic Health Records (EHRs) provide crucial information for clinical decision-making. However, their high-dimensionality, heterogeneity, and sparsity make clinical prediction challenging. Large Language Models (LLMs) allowed progress…

Computation and Language · Computer Science 2026-01-28 Jesus Lovon-Melgarejo , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

The machine learning modeling process conventionally culminates in selecting a single model that maximizes a selected performance metric. However, this approach leads to abandoning a more profound analysis of slightly inferior models.…

Machine Learning · Computer Science 2024-10-28 Katarzyna Kobylińska , Mateusz Krzyziński , Rafał Machowicz , Mariusz Adamek , Przemysław Biecek

Fine-grained entity typing (FET) is the task of identifying specific entity types at a fine-grained level for entity mentions based on their contextual information. Conventional methods for FET require extensive human annotation, which is…

Computation and Language · Computer Science 2023-10-13 Siru Ouyang , Jiaxin Huang , Pranav Pillai , Yunyi Zhang , Yu Zhang , Jiawei Han

This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor…

Machine Learning · Statistics 2016-09-21 Shalmali Joshi , Suriya Gunasekar , David Sontag , Joydeep Ghosh

AI systems in high-consequence domains such as defense, intelligence, and disaster response must detect rare, high-impact events while operating under tight resource constraints. Traditional annotation strategies that prioritize label…

Machine Learning · Computer Science 2025-05-22 Dave Cook , Tim Klawa

Prototype-based neural networks offer interpretable predictions by comparing inputs to learned, representative signal patterns anchored in training data. While such models have shown promise in the classification of physiological data, it…

Machine Learning · Computer Science 2026-05-28 Sahil Sethi , David Chen , Michael C. Burkhart , Nipun Bhandari , Bashar Ramadan , Brett Beaulieu-Jones

Intensive Care Units are complex, data-rich environments where critically ill patients are treated using variety of clinical equipment. The data collected using this equipment can be used clinical staff to gain insight into the condition of…

Human-Computer Interaction · Computer Science 2024-10-23 Marceli Wac , Raul Santos-Rodriguez , Chris McWilliams , Christopher Bourdeaux

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Digital pathology has seen the advent of a wealth of foundational models (FM), yet to date their performance on cell phenotyping has not been benchmarked in a unified manner. We therefore propose PhenoBench: A comprehensive benchmark for…

End-to-end models in general, and Recurrent Neural Network Transducer (RNN-T) in particular, have gained significant traction in the automatic speech recognition community in the last few years due to their simplicity, compactness, and…

Computation and Language · Computer Science 2020-11-17 Duc Le , Gil Keren , Julian Chan , Jay Mahadeokar , Christian Fuegen , Michael L. Seltzer

Achieving robust performance and fairness across diverse patient populations remains a challenge in developing clinically deployable deep learning models for diagnostic imaging. Synthetic data generation has emerged as a promising strategy…

The automated generation of research workflows is essential for improving the reproducibility of research and accelerating the paradigm of "AI for Science". However, existing methods typically extract merely fragmented procedural components…

Computation and Language · Computer Science 2025-09-24 Heng Zhang , Chengzhi Zhang

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision…

Computation and Language · Computer Science 2026-03-17 Fariba Afrin Irany , Sampson Akwafuo

De-identification is the process of removing 18 protected health information (PHI) from clinical notes in order for the text to be considered not individually identifiable. Recent advances in natural language processing (NLP) has allowed…

Computation and Language · Computer Science 2018-10-04 Kaung Khin , Philipp Burckhardt , Rema Padman

Identifying complex phenotypes from high-dimensional biological data is challenging due to the intricate interdependencies among different physiological indicators. Traditional approaches often focus on detecting outliers in single…

Machine Learning · Statistics 2024-10-24 Yafei Shen , Tao Zhang , Zhiwei Liu , Kalliopi Kostelidou , Ying Xu , Ling Yang

Radiology report annotation is essential for clinical NLP, yet manual labeling is slow and costly. We present RadAnnotate, an LLM-based framework that studies retrieval-augmented synthetic reports and confidence-based selective automation…

Computation and Language · Computer Science 2026-03-18 Saisha Pradeep Shetty , Roger Eric Goldman , Vladimir Filkov

Background: Huntington's disease (HD) is a rare, genetically determined brain disorder that limits the life of the patient, although early prognosis of HD can substantially improve the patient's quality of life. Current HD prognosis methods…

Signal Processing · Electrical Eng. & Systems 2023-02-09 Sucheer Maddury