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Micro-sized cold atmospheric plasma (uCAP) has been developed to expand the applications of CAP in cancer therapy. In this paper, uCAP devices with different nozzle lengths were applied to investigate effects on both brain (glioblastoma…

Tissues and Organs · Quantitative Biology 2018-04-24 Zhitong Chen , Li Lin , Qinmin Zheng , Jonathan H. Sherman , Jerome Canady , Barry Trink , Michael Keidar

Here we report the development of SPRAY, a massively parallel GPU accelerated, smoothed particle hydrodynamics (SPH)-based, radiation hydrodynamics (RHD) code designed specifically for simulating high intensity laser-plasma interactions.…

Computational Physics · Physics 2026-04-23 Min Ki Jung , Hakhyeon Kim , Su-San Park , Eung Soo Kim , Yong-Su Na , Sang June Hahn

The goal to control short-wavelength radiation for the investigation and manipulation of ultrafast dynamics in quantum systems coevolves with the growing availability of extreme-ultraviolet (XUV) and x-ray sources from high-harmonic…

Radiation therapy is considered to be one of important treatment protocols for cancers. Radiation therapy employs several beams of ionizing radiation to kill cancer tumors, but such irradiation also causes damage to normal tissues.…

Optimization and Control · Mathematics 2016-12-06 Shogo Kishimoto , Makoto Yamashita

Background: Ultra-high-dose-rate (UHDR) radiation therapy has demonstrated promising potential in reducing toxicity to organs-at-risk (OARs). Proton therapy is uniquely positioned to deliver UHDR by leveraging the Bragg peak in conjunction…

Medical Physics · Physics 2025-04-30 Jiayue Han , Ya-Nan Zhu , Aoxiang Wang , Wangyao Li , Yuting Lin , Hao Gao

Spin-polarized particle beams are of interest for applications like deep-inelastic scattering, e.g. to gain further understanding of the proton's nuclear structure. With the advent of high-intensity laser facilities, laser-plasma-based…

Plasma Physics · Physics 2025-11-06 Lars Reichwein , Zheng Gong , Chuan Zheng , Liangliang Ji , Alexander Pukhov , Markus Büscher

The remarkable temporal properties of ultra-short pulsed lasers in combination with novel beam shaping concepts enable the development of completely new material processing strategies. We demonstrate the benefit of employing focus…

One of the key insights in the emerging field of non-Hermitian photonics is that well-established concepts like the laser can be operated in reverse to realize a 'coherent perfect absorber' (CPA). While conceptually appealing, such CPAs are…

A large distance propagation in turbulent atmosphere results in disintegration of laser beam into speckles. We find that the most intense speckle approximately preserves both the Gaussian shape and the diameter of the initial collimated…

Optics · Physics 2019-12-10 Pavel M. Lushnikov , Natalia Vladimirova

We present a novel and straightforward approach for the spatio-spectral characterization of ultrashort pulses. This minimally intrusive method relies on placing a mask with specially arranged pinholes in the beam path before the focusing…

We present an initial examination of a novel approach to accurately position a patient during head and neck intensity modulated radiotherapy (IMRT). Position-based visual-servoing of a radio-transparent soft robot is used to control the…

Robotics · Computer Science 2017-02-08 Olalekan Ogunmolu , Xuejun Gu , Steve Jiang , Nicholas Gans

Proposals to reach the next generation of laser intensities through Raman or Brillouin backscattering have centered on optical frequencies. Higher frequencies are beyond the range of such methods mainly due to the wave damping that…

Plasma Physics · Physics 2017-12-05 Yuan Shi , Hong Qin , Nathaniel J. Fisch

The control of large-scale quantum information processors based on arrays of trapped ions requires a means to route and focus multiple laser beams to each of many trapping sites in parallel. Here, we combine arrays of fibres, 3D…

Total Body Photography (TBP) is becoming a useful screening tool for patients at high risk for skin cancer. While much progress has been made, existing TBP systems can be further improved for automatic detection and analysis of suspicious…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Wei-Lun Huang , Joshua Liu , Davood Tashayyod , Jun Kang , Amir Gandjbakhche , Misha Kazhdan , Mehran Armand

Many nuclear safety applications need fast, portable, and accurate imagers to better locate radiation sources. The Rotating Scatter Mask (RSM) system is an emerging device with the potential to meet these needs. The main challenge is the…

Signal Processing · Electrical Eng. & Systems 2023-08-01 Yilun Zhu , Clayton Scott , Darren Holland , George Landon , Aaron Fjeldsted , Azaree Lintereur

Efficient coupling of intense laser pulses to solid-density matter is critical to many applications including ion acceleration for cancer therapy. At relativistic intensities, the focus has been mainly on investigating various laser beams…

Plasma Physics · Physics 2015-09-24 L. L. Ji , J. Snyder , A. Pukhov , R. R. Freeman , K. U. Akli

Recently a coherent optical process called plasmon injection ($\Pi$) scheme, which employs an auxiliary source, has been introduced as a new technique to compensate losses in metamaterials. In this work, a physical implementation of the…

Optics · Physics 2018-05-09 Anindya Ghoshroy , Wyatt Adams , Xu Zhang , Durdu O. Guney

The `Laser-hybrid Accelerator for Radiobiological Applications', LhARA, is conceived as a novel, uniquely-flexible facility dedicated to the study of radiobiology. The technologies demonstrated in LhARA, which have wide application, will be…

Due to the highly inhomogeneous distributions of refractive indexes, light propagation in complex media such as biological tissue experiences multiple light scattering events. The suppression and control of multiple light scattering events…

Hyperfine atomic states are among the most promising candidates for qubit encoding in quantum information processing. In atomic systems, hyperfine transitions are typically driven through a two-photon Raman process by a laser field which is…