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Related papers: Benchmarking Computational Pathology Foundation Mo…

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Advancements in artificial intelligence have driven the development of numerous pathology foundation models capable of extracting clinically relevant information. However, there is currently limited literature independently evaluating these…

The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts. However, model training is often…

Foundation models, trained on vast amounts of data using self-supervised techniques, have emerged as a promising frontier for advancing artificial intelligence (AI) applications in medicine. This study evaluates three different…

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Foundation models are increasingly developed in computational pathology (CPath) given their promise in facilitating many downstream tasks. While recent studies have evaluated task performance across models, less is known about the structure…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Vaibhav Mishra , William Lotter

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

To handle the large scale of whole slide images in computational pathology, most approaches first tessellate the images into smaller patches, extract features from these patches, and finally aggregate the feature vectors with…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Benedikt Roth , Valentin Koch , Sophia J. Wagner , Julia A. Schnabel , Carsten Marr , Tingying Peng

Recent advancements in foundation models have transformed computer vision, driving significant performance improvements across diverse domains, including digital histopathology. However, the advantages of domain-specific histopathology…

Computer Vision and Pattern Recognition · Computer Science 2025-02-05 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Enrico Grisan

The deep learning field is converging towards the use of general foundation models that can be easily adapted for diverse tasks. While this paradigm shift has become common practice within the field of natural language processing, progress…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Joana Palés Huix , Adithya Raju Ganeshan , Johan Fredin Haslum , Magnus Söderberg , Christos Matsoukas , Kevin Smith

In colonoscopy, 80% of the missed polyps could be detected with the help of Deep Learning models. In the search for algorithms capable of addressing this challenge, foundation models emerge as promising candidates. Their zero-shot or…

Recent vision foundation models (VFMs) have demonstrated proficiency in various tasks but require supervised fine-tuning to perform the task of semantic segmentation effectively. Benchmarking their performance is essential for selecting…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Tommie Kerssies , Daan de Geus , Gijs Dubbelman

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Weakly supervised semantic segmentation (WSSS) in histopathology relies heavily on classification backbones, yet these models often localize only the most discriminative regions and struggle to capture the full spatial extent of tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Khang Le , Ha Thach , Anh M. Vu , Trang T. K. Vo , Han H. Huynh , David Yang , Minh H. N. Le , Thanh-Huy Nguyen , Akash Awasthi , Chandra Mohan , Zhu Han , Hien Van Nguyen

Vision Foundation Model (VFM) such as the Segment Anything Model (SAM) and Contrastive Language-Image Pre-training Model (CLIP) has shown promising performance for segmentation and detection tasks. However, although SAM excels in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Kunliang Liu , Jianming Wang , Rize Jin , Wonjun Hwang , Tae-Sun Chung

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Carolin Teuber , Anwai Archit , Tobias Boothe , Peter Ditte , Jochen Rink , Constantin Pape
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