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Deep convolutional neural networks (CNNs) have been widely used for medical image segmentation. In most studies, only the output layer is exploited to compute the final segmentation results and the hidden representations of the deep learned…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Sheng He , Yanfang Feng , P. Ellen Grant , Yangming Ou

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Boram Song , Seoung Wan Chae , Jin Tae Kwak

Precise image segmentation provides clinical study with instructive information. Despite the remarkable progress achieved in medical image segmentation, there is still an absence of a 3D foundation segmentation model that can segment a wide…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Yuxin Du , Fan Bai , Tiejun Huang , Bo Zhao

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

The deployment of foundation models for medical imaging has demonstrated considerable success. However, their training overheads associated with downstream tasks remain substantial due to the size of the image encoders employed, and the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Chengxi Zeng , Yuxuan Jiang , Fan Zhang , Alberto Gambaruto , Tilo Burghardt

Foundation models have revolutionized computer vision by achieving vastly superior performance across diverse tasks through large-scale pretraining on extensive datasets. However, their application in surgical computer vision has been…

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

Recent advances in foundational Vision Language Models (VLMs) have reshaped the evaluation paradigm in computer vision tasks. These foundational models, especially CLIP, have accelerated research in open-vocabulary computer vision tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 M. Arda Aydın , Efe Mert Çırpar , Elvin Abdinli , Gozde Unal , Yusuf H. Sahin

The segmentation of histopathological whole slide images into tumourous and non-tumourous types of tissue is a challenging task that requires the consideration of both local and global spatial contexts to classify tumourous regions…

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Existing semantic segmentation approaches are often limited by costly pixel-wise annotations and predefined classes. In this work, we present CLIP-S$^4$ that leverages self-supervised pixel representation learning and vision-language models…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Wenbin He , Suphanut Jamonnak , Liang Gou , Liu Ren

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Ruiwen Ding , James Hall , Neil Tenenholtz , Kristen Severson

Foundation models have substantially advanced computational pathology by learning transferable visual representations from large histological datasets, yet their performance varies widely across tasks due to differences in training data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Wenhui Lei , Yusheng Tan , Anqi Li , Hanyu Chen , Hengrui Tian , Ruiying Li , Zhengqun Jiang , Fang Yan , Xiaofan Zhang , Shaoting Zhang

Accurate classification of skin lesions from dermatoscopic images is essential for diagnosis and treatment of skin cancer. In this study, we investigate the utility of a dermatology-specific foundation model, PanDerm, in comparison with two…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Amirreza Mahbod , Rupert Ecker , Ramona Woitek

Recently, vision-language pre-trained models have emerged in computational pathology. Previous works generally focused on the alignment of image-text pairs via the contrastive pre-training paradigm. Such pre-trained models have been applied…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Anh Tien Nguyen , Trinh Thi Le Vuong , Jin Tae Kwak

Biomedical image analysis is fundamental for biomedical discovery in cell biology, pathology, radiology, and many other biomedical domains. Holistic image analysis comprises interdependent subtasks such as segmentation, detection, and…

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