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The natural indirect effect (NIE) and mediation proportion (MP) are two measures of primary interest in mediation analysis. The standard approach for estimating NIE and MP is through the product method, which involves a model for the…

Methodology · Statistics 2021-08-20 Chao Cheng , Donna Spiegelman , Fan Li

Graphical tests assess whether a function of interest departs from an envelope of functions generated under a simulated null distribution. This approach originated in spatial statistics, but has recently gained some popularity in functional…

Methodology · Statistics 2020-06-25 Meng Xu , Philip T. Reiss

Pseudo-marginal Metropolis-Hastings (pmMH) is a powerful method for Bayesian inference in models where the posterior distribution is analytical intractable or computationally costly to evaluate directly. It operates by introducing…

Computation · Statistics 2016-08-06 Johan Dahlin , Fredrik Lindsten , Joel Kronander , Thomas B. Schön

In many settings, robust data analysis involves computational methods for uncertainty quantification and statistical inference. To design frequentist studies that leverage robust analysis methods, suitable sample sizes to achieve desired…

Methodology · Statistics 2025-12-19 Luke Hagar , Andrew J. Martin

To date, attribute discretization is typically performed by replacing the original set of continuous features with a transposed set of discrete ones. This paper provides support for a new idea that discretized features should often be used…

Machine Learning · Computer Science 2018-02-12 Avi Rosenfeld , Ron Illuz , Dovid Gottesman , Mark Last

Many methods have been developed to estimate the set of relevant variables in a sparse linear model Y= XB+e where the dimension p of B can be much higher than the length n of Y. Here we propose two new methods based on multiple hypotheses…

Statistics Theory · Mathematics 2012-06-12 Florian Rohart

Pseudospectral collocation methods and finite difference methods have been used for approximating an important family of soliton like solutions of the mKdV equation. These solutions present a structural instability which make difficult to…

Numerical Analysis · Mathematics 2011-09-29 Carlos Gorria , Miguel A. Alejo , Luis Vega

We introduce an extension to the Discrete Multiplier Method (DMM), called Minimal $\ell_2$ Norm Discrete Multiplier Method (MN-DMM), where conservative finite difference schemes for dynamical systems with multiple conserved quantities are…

Numerical Analysis · Mathematics 2025-06-19 Erick Schulz , Andy T. S. Wan

Counting experiments often rely on Monte Carlo simulations for predictions of Poisson expectations. The accompanying uncertainty from the finite Monte Carlo sample size can be incorporated into parameter estimation by modifying the Poisson…

Instrumentation and Methods for Astrophysics · Physics 2020-04-22 Thorsten Glüsenkamp

This essay looks at decision-making with interval-valued probability measures. Existing decision methods have either supplemented expected utility methods with additional criteria of optimality, or have attempted to supplement the…

Artificial Intelligence · Computer Science 2013-04-15 Ronald P. Loui

In a recent opinion article, Muff et al. recapitulate well-known objections to the Neyman-Pearson Null-Hypothesis Significance Testing (NHST) framework and call for reforming our practices in statistical reporting. We agree with them on…

Quantitative Methods · Quantitative Biology 2022-05-30 Florian Hartig , Frédéric Barraquand

The Metropolis-Hastings algorithm allows one to sample asymptotically from any probability distribution $\pi$. There has been recently much work devoted to the development of variants of the MH update which can handle scenarios where such…

Computation · Statistics 2018-03-28 Christophe Andrieu , Arnaud Doucet , Sinan Yıldırım , Nicolas Chopin

Multiple comparison procedures that control a family-wise error rate or false discovery rate provide an achieved error rate as the adjusted p-value for each hypothesis tested. However, since such p-values are not probabilities that the null…

Methodology · Statistics 2013-09-03 David R. Bickel

Predictive mean matching (PMM) is a popular imputation strategy that imputes missing values by borrowing observed values from other cases with similar expectations. We show that, unlike other imputation strategies, PMM is not guaranteed to…

Methodology · Statistics 2025-07-01 Paul T. von Hippel

Introductory statistical inference texts and courses treat the point estimation, hypothesis testing, and interval estimation problems separately, with primary emphasis on large-sample approximations. Here I present an alternative approach…

Other Statistics · Statistics 2017-07-14 Ryan Martin

Stratification in both the design and analysis of randomized clinical trials is common. Despite features in automated randomization systems to re-confirm the stratifying variables, incorrect values of these variables may be entered. These…

Methodology · Statistics 2023-07-24 Neal Thomas

In many practical applications of multiple hypothesis testing using the False Discovery Rate (FDR), the given hypotheses can be naturally partitioned into groups, and one may not only want to control the number of false discoveries (wrongly…

Methodology · Statistics 2016-11-01 Rina Foygel Barber , Aaditya Ramdas

In genome-wide epigenetic studies, exposures (e.g., Single Nucleotide Polymorphisms) affect outcomes (e.g., gene expression) through intermediate variables such as DNA methylation. Mediation analysis offers a way to study these intermediate…

Methodology · Statistics 2025-12-08 Asmita Roy , Xianyang Zhang

As a result of a rather long-time research started in 2016, this theory whose structure is based on a fixed variable and an algebraic inequality, improves and somehow generalizes the well-known least squares theory. In fact, the fixed…

Statistics Theory · Mathematics 2023-10-24 Mohammad Masjed-Jamei

In this paper we develop a very general class of bivariate discrete distributions. The basic idea is very simple. The marginals are obtained by taking the random geometric sum of a baseline distribution function. The proposed class of…

Methodology · Statistics 2018-05-22 Debasis Kundu
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