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Diffusion tensor imaging (DTI) plays a key role in analyzing the physical structures of biological tissues, particularly in reconstructing fiber tracts of the human brain in vivo. On the one hand, eigenvalues of diffusion tensors (DTs)…
Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…
Deep neural networks are applied in more and more areas of everyday life. However, they still lack essential abilities, such as robustly dealing with spatially transformed input signals. Approaches to mitigate this severe robustness issue…
Carefully engineered radiofrequency (RF) pulses play a key role in a number of systems such as mobile phone, radar, and magnetic resonance imaging. The design of an RF waveform, however, is often posed as an inverse problem with no general…
Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) enables us to probe the microstructural arrangement of cardiomyocytes within the myocardium in vivo and non-invasively, which no other imaging modality allows. This innovative technology…
Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain stimulation technique enabling cortical and deep brain targeting with unprecedented spatial accuracy. Given the high rate of adoption by new users with varying…
Automatic brain tumor segmentation from Magnetic Resonance Imaging (MRI) data plays an important role in assessing tumor response to therapy and personalized treatment stratification.Manual segmentation is tedious and…
In-scanner motion degrades the quality of magnetic resonance imaging (MRI) thereby reducing its utility in the detection of clinically relevant abnormalities. We introduce a deep learning-based MRI artifact reduction model (DMAR) to…
Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…
A time-varying microwave photonic filter (TV-MPF) based on stimulated Brillouin scattering (SBS) is proposed and utilized to suppress the in-band noise of broadband arbitrary microwave waveforms, thereby improving the signal-to-noise ratio…
In this work, we propose a learning framework for identifying synapses using a deep and wide multi-scale recursive (DAWMR) network, previously considered in image segmentation applications. We apply this approach on electron microscopy data…
Functional near-infrared spectroscopy (fNIRS) is a non-invasive, low-cost method used to study the brain's blood flow pattern. Such patterns can enable us to classify performed by a subject. In recent research, most classification systems…
Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…
Decoding motor performance from brain signals offers promising avenues for adaptive deep brain stimulation (aDBS) for Parkinson's disease (PD). In a two-center cohort of 19 PD patients executing a drawing task, we decoded motor performance…
Supervised Deep-Learning (DL)-based reconstruction algorithms have shown state-of-the-art results for highly-undersampled dynamic Magnetic Resonance Imaging (MRI) reconstruction. However, the requirement of excessive high-quality…
We propose a noninvasive and dispersive framework for estimating the spatially nonuniform conductivity of brain tumors using MR images. The method consists of two components: (i) voxel-wise assignment of tumor conductivity based on…
This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…
In this work, we investigate the use of spatio-temporalImplicit Neural Representations (INRs) for dynamic X-ray computed tomography (XCT) reconstruction under interlaced acquisition schemes. The proposed approach combines ADMM-based…
We introduce a wavefront shaping protocol for focusing inside disordered media based on a generalization of the established Wigner-Smith time-delay operator. The key ingredient for our approach is the scattering (or transmission) matrix of…
Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…