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For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

Neurons and Cognition · Quantitative Biology 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure…

Systems and Control · Electrical Eng. & Systems 2023-12-14 Mobina Zibandepour , Akram Shojaei , Arash Abbasi Larki , Mehdi Delrobaei

Objective: The strengths of Electrical Impedance Tomography (EIT) are its capability of imaging the internal body by using a noninvasive, radiation safe technique, and the absence of known hazards. In this paper we introduce a novel idea of…

Signal Processing · Electrical Eng. & Systems 2022-03-08 Sebastien Martin

Spinal cord injury (SCI) is a debilitating condition that often results in significant motor and sensory deficits, impacting the quality of life. Current rehabilitation methods, including physical therapy and electrical stimulation, offer…

Neurons and Cognition · Quantitative Biology 2024-12-18 Ruidong Cheng , Yuling Shao , Xi Li , Li Zhang , Zehao Sheng , Chenyang Li , Xu Xie , Huilin Mou , Weidong Chen , Shaomin Zhang , Yuchen Xu , Minmin Wang

Deep Brain Stimulation (DBS) is an established and powerful treatment method in various neurological disorders. It involves chronically delivering electrical pulses to a certain stimulation target in the brain in order to alleviate the…

Systems and Control · Electrical Eng. & Systems 2023-10-03 Anna Franziska Frigge , Alexander Medvedev , Elena Jiltsova , Dag Nyholm

A new type of non-invasive deep-brain stimulation is conceived and demonstrated by computer simulations. The process is based on spatio-temporal Fourier synthesis using multiple electrode pairs with sinusoidal current drive to limit skin…

General Physics · Physics 2024-08-02 Laszlo B. Kish , Andrea Antal

Deep Brain Stimulation (DBS) stands as an effective intervention for alleviating the motor symptoms of Parkinson's disease (PD). Traditional commercial DBS devices are only able to deliver fixed-frequency periodic pulses to the basal…

Machine Learning · Computer Science 2024-03-12 Hao-Lun Hsu , Qitong Gao , Miroslav Pajic

Electrical impedance tomography (EIT) is a promising technique for biomedical imaging. The strength of EIT is its ability to reconstruct images of the body's internal structures through radiation-safe techniques. EIT is regarded as safe for…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Sebastien Martin

We introduce a metasurface-based system for the microwave hyperthermia treatment of brain tumors, where the metasurface is designed by the time-reversal technique for optimal focusing at the location of the tumor. Compared to previous…

Medical Physics · Physics 2023-01-04 Mohamad J. Hajiahmadi , Reza Faraji-Dana , Christophe Caloz

Background: Spinal cord injury (SCI) rehabilitation remains a major clinical challenge, with limited treatment options for functional recovery. Temporal interference (TI) electrical stimulation has emerged as a promising non-invasive…

Medical Physics · Physics 2025-03-07 Xu Xie , Yuchen Xu , Huilin Mou , Xi Li , Li Zhang , Zehao Sheng , Weidong Chen , Shaomin Zhang , Ruidong Cheng , Minmin Wang

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

Deep Brain Stimulation (DBS) is a therapy widely used for treating the symptoms of neurological disorders. Electrical pulses are chronically delivered in DBS to a disease-specific brain target via a surgically implanted electrode. The…

Systems and Control · Electrical Eng. & Systems 2024-10-24 Anna Franziska Frigge , Elena Jiltsova , Fredrik Olsson , Dag Nyholm , Alexander Medvedev

We propose a novel Neural Steering technique that adapts the target area of a spatial-aware multi-microphone sound source separation algorithm during inference without the necessity of retraining the deep neural network (DNN). To achieve…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-23 Martin Strauss , Wolfgang Mack , María Luis Valero , Okan Köpüklü

Electromagnetic stimulation of the human brain is a key tool for the neurophysiological characterization and diagnosis of several neurological disorders. Transcranial magnetic stimulation (TMS) is one procedure that is commonly used…

Machine Learning · Computer Science 2020-02-04 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of…

Signal Processing · Electrical Eng. & Systems 2022-08-23 Arsalan Heidarpanah

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

Deep brain stimulation (DBS) is a surgical treatment for Parkinson's Disease. Static models based on quasi-static approximation are common approaches for DBS modeling. While this simplification has been validated for bioelectric sources,…

Neurons and Cognition · Quantitative Biology 2016-08-18 Pablo A. Alvarado , Mauricio A. Álvarez , Álvaro A. Orozco

This work presents a systematic design of a metasurface-based microwave hyperthermia system, leveraging the time-reversal technique to achieve precise focusing of electromagnetic energy at deep-seated brain tumors. The manuscript includes…

Medical Physics · Physics 2025-09-19 Alireza Rahmani , Mohammad Javad Hajiahmadi , Reza Faraji-Dana

Deep Brain Stimulation (DBS) is an effective treatment for Parkinson's disease, but conventional fixed-parameter stimulation can reduce battery life and cause side effects while failing to adapt to changing neural dynamics. Recent…

In this paper we present an efficient model of the neuronal potentials recorded by a deep brain stimulation microelectrode (DBS MER) in the subthalamic nucleus. It is shown that a computationally efficient filtered point process consisting…

Neurons and Cognition · Quantitative Biology 2016-07-05 Kristian J. Weegink , Paul A. Bellette , John J. Varghese , Peter A. Silburn , Paul A. Meehan , Andrew P. Bradley
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