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Deep brain stimulation (DBS) is an advanced surgical treatment for the symptoms of Parkinson's disease (PD), involving electrical stimulation of neurons within the basal ganglia region of the brain. DBS is traditionally delivered in an…

Systems and Control · Electrical Eng. & Systems 2025-06-19 Cédric Join , Jakub Orłowski , Antoine Chaillet , Madeleine Lowery , Hugues Mounier , Michel Fliess

The electron density is a key parameter to characterize any plasma. Most of the plasma applications and research in the area of low-temperature plasmas (LTPs) are based on the accurate estimations of plasma density and plasma temperature.…

Objective: The objective of this study is to develop and evaluate a systematic approach to optimize Deep Brain Stimulation (DBS) parameters, addressing the challenge of identifying patient-specific settings and optimal stimulation targets…

Systems and Control · Electrical Eng. & Systems 2026-01-13 Anna Franziska Frigge , Lina Uggla , Elena Jiltsova , Markus Fahlström , Dag Nyholm , Alexander Medvedev

Emerging research in edge devices and micro-controller units (MCU) enables on-device computation of Deep Learning Training and Inferencing tasks. More recently, contemporary trends focus on making the Deep Neural Net (DNN) Models runnable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-30 Ziliang Zhang

Objective:We propose a novel iterative-optimizationinspired direct targeting strategy (DTS) for smart nanosystems, which harness swarms of externally manipulable nanoswimmers assembled by magnetic nanoparticles (MNPs) for knowledgeaided…

Medical Physics · Physics 2019-01-03 Yifan Chen , Muhammad Ali , Shaolong Shi , U Kei Cheang

Millimeter Wave (mmWave) communications rely on highly directional beams to combat severe propagation loss. In this paper, an adaptive beam search algorithm based on spatial scanning, called Iterative Deactivation and Beam Shifting (IDBS),…

Information Theory · Computer Science 2020-05-05 Chunshan Liu , Min Li , Lou Zhao , Philip Whiting , Stephen V. Hanly , Iain B. Collings

Epilepsy is the fourth most common neurological disorder and affects people of all ages worldwide. Deep Brain Stimulation (DBS) has emerged as an alternative treatment option when anti-epileptic drugs or resective surgery cannot lead to…

Image and Video Processing · Electrical Eng. & Systems 2022-01-27 Han Liu , Kathryn L. Holloway , Dario J. Englot , Benoit M. Dawant

Deep Brain Stimulation (DBS) is a well-established neurosurgical treatment aiming at symptom alleviation in a range of neurological and psychiatric diseases. Computational models of DBS are widely used to investigate the effects of…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Anna Franziska Frigge , Alexander Medvedev

In recent years, non-invasive neuro-modulation methods such as Focused Ultrasound (FUS) have gained popularity. The aim of this work is to introduce the use of existing open-source technology for surgical navigation to the field of…

Medical Physics · Physics 2019-09-30 Frank Preiswerk , Spencer T. Brinker , Nathan J. McDannold , Timothy Y. Mariano

It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…

Deep brain stimulation (DBS) is an established intervention for Parkinson's disease (PD), but conventional open-loop systems lack adaptability, are energy-inefficient due to continuous stimulation, and provide limited personalization to…

Machine Learning · Computer Science 2025-07-10 Harsh Ravivarapu , Gaurav Bagwe , Xiaoyong Yuan , Chunxiu Yu , Lan Zhang

Deep brain stimulation (DBS) is an effective therapy as an alternative to pharmaceutical treatments for Parkinson's disease (PD). Aside from factors such as instrumentation, treatment plans, and surgical protocols, the success of the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Yiming Xiao , Jonathan C. Lau , Dimuthu Hemachandra , Greydon Gilmore , Ali R. Khan , Terry M. Peters

Automated brain tumor segmentation based on deep learning (DL) has achieved promising performance. However, it generally relies on annotated images for model training, which is not always feasible in clinical settings. Therefore, the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Xinru Zhang , Ni Ou , Chenghao Liu , Zhizheng Zhuo , Yaou Liu , Chuyang Ye

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

Neurons and Cognition · Quantitative Biology 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…

Signal Processing · Electrical Eng. & Systems 2024-03-14 Loraine Franke , Tae Young Park , Jie Luo , Yogesh Rathi , Steve Pieper , Lipeng Ning , Daniel Haehn

Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…

Neurons and Cognition · Quantitative Biology 2026-04-02 William J. Tyler

Diffusion Tensor Imaging (DTI) allows estimating the position, orientation and dimension of bundles of nerve pathways. This non-invasive imaging technique takes advantage of the diffusion of water molecules and determines the diffusion…

Computer Vision and Pattern Recognition · Computer Science 2011-03-09 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic and radiotherapy (RT) planning tool, offering detailed insights into the anatomy of the human body. The extensive scan time is stressful for patients, who must remain motionless…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Shahinur Alam , Jinsoo Uh , Alexander Dresner , Chia-ho Hua , Khaled Khairy

Intraoperative ultrasound (iUS) imaging has the potential to improve surgical outcomes in brain surgery. However, its interpretation is challenging, even for expert neurosurgeons. In this work, we designed the first patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Reuben Dorent , Erickson Torio , Nazim Haouchine , Colin Galvin , Sarah Frisken , Alexandra Golby , Tina Kapur , William Wells

Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…

Neurons and Cognition · Quantitative Biology 2025-05-16 Ekaterina Kuzmina , Dmitrii Kriukov , Mikhail Lebedev , Dmitry V. Dylov