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Persistent homology, an algebraic method for discerning structure in abstract data, relies on the construction of a sequence of nested topological spaces known as a filtration. Two-parameter persistent homology allows the analysis of data…

Computational Geometry · Computer Science 2022-07-08 Anway De , Thong Vo , Matthew Wright

Proteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics and transport is one of most challenging tasks in biological science. In the present work, persistent homology is,…

Biomolecules · Quantitative Biology 2014-12-10 Kelin Xia , Guo-Wei Wei

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

We present a machine learning approach that leverages persistent homology to classify bacterial flagellar motors into two functional states: rotated and stalled. By embedding protein structural data into a topological framework, we extract…

Biomolecules · Quantitative Biology 2025-12-19 Zakaria Lamine , Abdelatif Hafid , Mohamed Rahouti

We present an algorithm for computing the barcode of the image of a morphisms in persistent homology induced by an inclusion of filtered finite-dimensional chain complexes. These algorithms make use of the clearing optimization and can be…

Algebraic Topology · Mathematics 2022-01-13 Ulrich Bauer , Maximilian Schmahl

We present a parallelizable algorithm for computing the persistent homology of a filtered chain complex. Our approach differs from the commonly used reduction algorithm by first computing persistence pairs within local chunks, then…

Algebraic Topology · Mathematics 2013-03-05 Ulrich Bauer , Michael Kerber , Jan Reininghaus

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

Persistent homology (PH) is a method for generating topology-inspired representations of data. Empirical studies that investigate the properties of PH, such as its sensitivity to perturbations or ability to detect a feature of interest,…

Algebraic Topology · Mathematics 2024-03-05 Shuang Liang , Renata Turkeš , Jiayi Li , Nina Otter , Guido Montúfar

Techniques from computational topology, in particular persistent homology, are becoming increasingly relevant for data analysis. Their stable metrics permit the use of many distance-based data analysis methods, such as multidimensional…

Algebraic Topology · Mathematics 2021-01-20 Bastian Rieck , Filip Sadlo , Heike Leitte

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

0-dimensional persistent homology is known, from a computational point of view, as the easy case. Indeed, given a list of $n$ edges in non-decreasing order of filtration value, one only needs a union-find data structure to keep track of the…

Computational Geometry · Computer Science 2023-12-12 Marc Glisse

Persistent homology is a popular and powerful tool for capturing topological features of data. Advances in algorithms for computing persistent homology have reduced the computation time drastically -- as long as the algorithm does not…

Computational Geometry · Computer Science 2013-10-03 Ulrich Bauer , Michael Kerber , Jan Reininghaus

Data analysis that uses the output of topological data analysis as input for machine learning algorithms has been the subject of extensive research. This approach offers a means of capturing the global structure of data. Persistent homology…

Machine Learning · Computer Science 2023-10-17 Naofumi Hama

Mathematical morphology is a theory and technique to collect features like geometric and topological structures in digital images. Given a target image, determining suitable morphological operations and structuring elements is a cumbersome…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Yucong Shen , Xin Zhong , Frank Y. Shih

This paper aims to discuss a method of quantifying the 'shape' of data, via a methodology called topological data analysis. The main tool within topological data analysis is persistent homology; this is a means of measuring the shape of…

Algebraic Topology · Mathematics 2022-09-14 Tristan Gowdridge , Nikolaos Devilis , Keith Worden

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Persistent Homology is a fairly new branch of Computational Topology which combines geometry and topology for an effective shape description of use in Pattern Recognition. In particular it registers through "Betti Numbers" the presence of…

Quantitative Methods · Quantitative Biology 2016-06-01 Massimo Ferri , Ivan Tomba , Andrea Visotti , Ignazio Stanganelli

Topological Data Analysis (TDA) combines computational topology and data science to extract and analyze intrinsic topological and geometric structures in data set in a metric space. While the persistent homology (PH), a widely used tool in…

Computational Geometry · Computer Science 2025-04-15 Chuanshen Hu , Yu Wang , Kelin Xia , Ke Ye , Yipeng Zhang

We characterize structures such as monotonicity, convexity, and modality in smooth regression curves using persistent homology. Persistent homology is a key tool in topological data analysis that detects higher-dimensional topological…

Algebraic Topology · Mathematics 2025-10-28 Satish Kumar , Subhra Sankar Dhar

In this work we use the persistent homology method, a technique in topological data analysis (TDA), to extract essential topological features from the data space and combine them with deep learning features for classification tasks. In TDA,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Mariana Dória Prata Lima , Gilson Antonio Giraldi , Gastão Florêncio Miranda Junior