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We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

Early detection of lung cancer in chest radiographs (CXRs) is crucial for improving patient outcomes, yet nodule detection remains challenging due to their subtle appearance and variability in radiological characteristics like size,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Shreshtha Singh , Ashish Mittal , Manoj Tadepalli , Piyush Kumar , Preetham Putha

The scarcity of high-quality, labelled retinal imaging data, which presents a significant challenge in the development of machine learning models for ophthalmology, hinders progress in the field. Existing methods for synthesising Colour…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Junzhi Ning , Cheng Tang , Kaijing Zhou , Diping Song , Lihao Liu , Ming Hu , Wei Li , Huihui Xu , Yanzhou Su , Tianbin Li , Jiyao Liu , Jin Ye , Sheng Zhang , Yuanfeng Ji , Junjun He

The persistent challenge of medical image synthesis posed by the scarcity of annotated data and the need to synthesize `missing modalities' for multi-modal analysis, underscored the imperative development of effective synthesis methods.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Yuchen Mao , Hongwei Li , Wei Pang , Giorgos Papanastasiou , Guang Yang , Chengjia Wang

Recent advancements in ophthalmology foundation models such as RetFound have demonstrated remarkable diagnostic capabilities but require massive datasets for effective pre-training, creating significant barriers for development and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Qingshan Hou , Meng Wang , Peng Cao , Zou Ke , Xiaoli Liu , Huazhu Fu , Osmar R. Zaiane

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Kanishk Choudhary

Despite recent advances in deep generative modeling, skin lesion classification systems remain constrained by the limited availability of large, diverse, and well-annotated clinical datasets, resulting in class imbalance between benign and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Stathis Galanakis , Alexandros Koliousis , Stefanos Zafeiriou

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and AI systems can expand access to fundus photography screening. Current FDA-cleared systems primarily provide binary referral outputs, where this minimal output may…

Artificial Intelligence · Computer Science 2025-09-17 Nadim Barakat , William Lotter

Designing generative models for 3D structural brain MRI that synthesize morphologically-plausible and attribute-specific (e.g., age, sex, disease state) samples is an active area of research. Existing approaches based on frameworks like…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Alan Q. Wang , Fangrui Huang , Bailey Trang , Wei Peng , Mohammad Abbasi , Kilian Pohl , Mert Sabuncu , Ehsan Adeli

Effective dietary monitoring is critical for managing Type 2 diabetes, yet accurately estimating caloric intake remains a major challenge. While continuous glucose monitors (CGMs) offer valuable physiological data, they often fall short in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Adarsh Kumar

Recently, large-scale diffusion models have made impressive progress in text-to-image (T2I) generation. To further equip these T2I models with fine-grained spatial control, approaches like ControlNet introduce an extra network that learns…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Yifeng Xu , Zhenliang He , Shiguang Shan , Xilin Chen

Diabetic retinopathy (DR) is a complication of diabetes that severely affects eyes. It can be graded into five levels of severity according to international protocol. However, optimizing a grading model to have strong generalizability…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Yi Zhou , Boyang Wang , Xiaodong He , Shanshan Cui , Ling Shao

Foundation models (FMs) show great promise for robust downstream performance across medical imaging tasks and modalities, including cardiac magnetic resonance (CMR), following task-specific adaptation. However, adaptation using single-site…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Joan Perramon-Llussà , Amelia Jiménez-Sánchez , Grzegorz Skorupko , Fotis Avgoustidis , Carlos Martín-Isla , Karim Lekadir , Polyxeni Gkontra

Automated grading of diabetic retinopathy (DR) faces several critical challenges: subtle inter-grade visual distinctions in fine-grained lesion patterns, distributional discrepancies induced by heterogeneous imaging devices and acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yiqun Wang

This paper addresses the emerging task of recognizing multiple retinal diseases from wide-field (WF) and ultra-wide-field (UWF) fundus images. For an effective use of existing large amount of labeled color fundus photo (CFP) data and the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-25 Qijie Wei , Jingyuan Yang , Bo Wang , Jinrui Wang , Jianchun Zhao , Xinyu Zhao , Sheng Yang , Niranchana Manivannan , Youxin Chen , Dayong Ding , Jing Zhou , Xirong Li

Background/Aim. This study aims to predict Amyloid Positron Emission Tomography (AmyloidPET) status with multimodal retinal imaging and convolutional neural networks (CNNs) and to improve the performance through pretraining with synthetic…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 I. R. Slootweg , M. Thach , K. R. Curro-Tafili , F. D. Verbraak , F. H. Bouwman , Y. A. L. Pijnenburg , J. F. Boer , J. H. P. de Kwisthout , L. Bagheriye , P. J. González

In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Diabetic Retinopathy (DR) is a non-negligible eye disease among patients with Diabetes Mellitus, and automatic retinal image analysis algorithm for the DR screening is in high demand. Considering the resolution of retinal image is very…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Kang Zhou , Zaiwang Gu , Wen Liu , Weixin Luo , Jun Cheng , Shenghua Gao , Jiang Liu

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed
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