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Purpose: Probe-based Confocal Laser Endomicroscopy (pCLE) is a recent imaging modality that allows performing in vivo optical biopsies. The design of pCLE hardware, and its reliance on an optical fibre bundle, fundamentally limits the image…

Computer Vision and Pattern Recognition · Computer Science 2018-04-25 Daniele Ravì , Agnieszka Barbara Szczotka , Dzhoshkun Ismail Shakir , Stephen P Pereira , Tom Vercauteren

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Cardiac Magnetic Resonance (CMR) imaging is a vital non-invasive tool for diagnosing heart diseases and evaluating cardiac health. However, the limited availability of large-scale, high-quality CMR datasets poses a major challenge to the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Ziyu Li , Yujian Hu , Zhengyao Ding , Yiheng Mao , Haitao Li , Fan Yi , Hongkun Zhang , Zhengxing Huang

Confocal Laser Endomicroscope (CLE) is a novel handheld fluorescence imaging device that has shown promise for rapid intraoperative diagnosis of brain tumor tissue. Currently CLE is capable of image display only and lacks an automatic…

Due to the three-dimensional nature of CT- or MR-scans, generative modeling of medical images is a particularly challenging task. Existing approaches mostly apply patch-wise, slice-wise, or cascaded generation techniques to fit the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Paul Friedrich , Julia Wolleb , Florentin Bieder , Alicia Durrer , Philippe C. Cattin

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

We introduce CoLoRA (Convolutional Low-Rank Adaptation), a parameter-efficient fine-tuning method for convolutional neural networks (CNNs). CoLoRA extends LoRA to convolutional layers by decomposing kernel updates into lightweight depthwise…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Mariano Rivera , Angello Hoyos

Medical image segmentation has achieved remarkable advancements using deep neural networks (DNNs). However, DNNs often need big amounts of data and annotations for training, both of which can be difficult and costly to obtain. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Hengji Cui , Dong Wei , Kai Ma , Shi Gu , Yefeng Zheng

Multimodal large language models (MLLMs) hold promise for integrating diverse data modalities, but current medical adaptations such as LLaVA-Med often fail to fully exploit the synergy between color fundus photography (CFP) and optical…

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

Paucity of medical data severely limits the generalizability of diagnostic ML models, as the full spectrum of disease variability can not be represented by a small clinical dataset. To address this, diffusion models (DMs) have been…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Janet Wang , Yunbei Zhang , Zhengming Ding , Jihun Hamm

Medical imaging applications are highly specialized in terms of human anatomy, pathology, and imaging domains. Therefore, annotated training datasets for training deep learning applications in medical imaging not only need to be highly…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Arjun Krishna , Ge Wang , Klaus Mueller

3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Continual adaptation of deep generative models holds tremendous potential and critical importance, given their rapid and expanding usage in text and vision based applications. Incremental training, however, remains highly challenging due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Victor Enescu , Hichem Sahbi

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…

Computer Vision and Pattern Recognition · Computer Science 2017-05-03 Yehui Yang , Tao Li , Wensi Li , Haishan Wu , Wei Fan , Wensheng Zhang

Corneal diseases are the most common eye disorders. Deep learning techniques are used to per-form automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-30 Samer Kais Jameel , Sezgin Aydin , Nebras H. Ghaeb , Jafar Majidpour , Tarik A. Rashid , Sinan Q. Salih , P. S. JosephNg

Convolutional neural networks (CNNs) have been widely used in efficient image super-resolution. However, for CNN-based methods, performance gains often require deeper networks and larger feature maps, which increase complexity and inference…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Xinning Chai , Yao Zhang , Yuxuan Zhang , Zhengxue Cheng , Yingsheng Qin , Yucai Yang , Li Song

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia