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Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

Machine Learning · Computer Science 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Recent advances in Large Language Models (LLMs) and Large Reasoning Models (LRMs) have enabled agentic search systems that interleave multi-step reasoning with external tool use. However, existing frameworks largely rely on unstructured…

Information Retrieval · Computer Science 2025-12-29 Shuting Wang , Qiaolin Xia , Vich Wang , Herberttli , Bobsimons , Zhicheng Dou

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

Large language models can exhibit emergent reasoning behaviors, often manifested as recurring lexical patterns (e.g., "wait," indicating verification). However, complex reasoning trajectories remain sparse in unconstrained sampling, and…

Artificial Intelligence · Computer Science 2026-03-03 Po-Nien Kung , Zhen Yang , Jeffrey Luo , Cheng-Fu Yang , Haikang Deng , Zi-Yi Dou , Yinfei Yang , Nanyun Peng , Zhe Gan , Kai-Wei Chang

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

Machine Learning · Computer Science 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Large language models (LLMs) solve complex problems by generating multi-step reasoning traces. Yet these traces are typically analyzed from only one of two perspectives: the sequence of tokens across different reasoning steps in the…

Computation and Language · Computer Science 2026-03-25 Ruidi Chang , Jiawei Zhou , Hanjie Chen

Large-scale telecom and datacenter infrastructures rely on multi-layered service and resource models, where failures propagate across physical and logical components and affect multiple customers. Traditional approaches to root cause…

Artificial Intelligence · Computer Science 2026-01-13 Nicolas Tacheny

Most studies on machine learning in sensing systems focus on low-level perception tasks that process raw sensory data within a short time window. However, many practical applications, such as human routine modeling and occupancy tracking,…

Artificial Intelligence · Computer Science 2024-04-01 Xiaomin Ouyang , Mani Srivastava

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure…

Artificial Intelligence · Computer Science 2025-09-30 Hongjun Liu , Yinghao Zhu , Yuhui Wang , Yitao Long , Zeyu Lai , Lequan Yu , Chen Zhao

Clinical decision support systems are assisting physicians in providing care to patients. However, in the context of clinical pathway management such systems are rather limited as they only take the current state of the patient into account…

Computers and Society · Computer Science 2021-04-13 Hong Sun , Dörthe Arndt , Jos De Roo , Erik Mannens

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

Other Quantitative Biology · Quantitative Biology 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Temporal reasoning in multi-session dialogues presents a significant challenge which has been under-studied in previous temporal reasoning benchmarks. To bridge this gap, we propose a new evaluation task for temporal reasoning in…

Artificial Intelligence · Computer Science 2025-09-26 Yubin Ge , Salvatore Romeo , Jason Cai , Raphael Shu , Monica Sunkara , Yassine Benajiba , Yi Zhang

Cardiovascular diseases and heart failures in particular are the main cause of non-communicable disease mortality in the world. Constant patient monitoring enables better medical treatment as it allows practitioners to react on time and…

Artificial Intelligence · Computer Science 2021-04-21 Kordian Gontarska , Weronika Wrazen , Jossekin Beilharz , Robert Schmid , Lauritz Thamsen , Andreas Polze

Large language models (LLMs) have demonstrated strong performance and rapid progress in a wide range of medical reasoning tasks. However, their sequential autoregressive decoding forces inherently parallel clinical reasoning, such as…

Machine Learning · Computer Science 2026-04-17 Jianwen Chen , Xinyu Yang , Peng Xia , Arian Azarang , Yueh Z Lee , Gang Li , Hongtu Zhu , Yun Li , Beidi Chen , Huaxiu Yao

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

Eye-tracking data reveals valuable insights into users' cognitive states but is difficult to analyze due to its structured, non-linguistic nature. While large language models (LLMs) excel at reasoning over text, they struggle with temporal…

Human-Computer Interaction · Computer Science 2025-07-25 Dongyang Guo , Yasmeen Abdrabou , Enkeleda Thaqi , Enkelejda Kasneci

Visual transformation reasoning (VTR) is a vital cognitive capability that empowers intelligent agents to understand dynamic scenes, model causal relationships, and predict future states, and thereby guiding actions and laying the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Yuheng Ji , Yipu Wang , Yuyang Liu , Xiaoshuai Hao , Yue Liu , Yuting Zhao , Huaihai Lyu , Xiaolong Zheng
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