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Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large language models (LLMs) are increasingly being applied to clinical care, a domain where both accuracy and transparent reasoning are critical for safe and trustworthy deployment. Chain-of-thought (CoT) prompting, which elicits…

Computation and Language · Computer Science 2025-12-09 Jiageng Wu , Kevin Xie , Bowen Gu , Nils Krüger , Kueiyu Joshua Lin , Jie Yang

As large language models empower healthcare, intelligent clinical decision support has developed rapidly. Longitudinal electronic health records (EHR) provide essential temporal evidence for accurate clinical diagnosis and analysis.…

Computation and Language · Computer Science 2026-05-15 Zihan Deng , Xiaozhen Zhong , Chuanzhi Xu

Continuous latent-space reasoning offers a compact alternative to textual chain-of-thought for multimodal models, enabling high-dimensional visual evidence to be integrated without explicit reasoning tokens. However, we identify a…

Machine Learning · Computer Science 2026-05-05 Xin Zhang , Qiqi Tao , Jiawei Du , Moyun Liu , Joey Tianyi Zhou

Healthcare AI systems have historically faced challenges in merging contextual reasoning, long-term state management, and human-verifiable workflows into a cohesive framework. This paper introduces a completely innovative architecture and…

Artificial Intelligence · Computer Science 2025-12-08 Zag ElSayed , Craig Erickson , Ernest Pedapati

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

Computation and Language · Computer Science 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

Clinical notes in Electronic Health Records (EHRs) capture rich temporal information on events, clinician reasoning, and lifestyle factors often missing from structured data. Leveraging them for predictive modeling can be impactful for…

Computation and Language · Computer Science 2026-05-08 Rochana Chaturvedi , Yue Zhou , Andrew D. Boyd , Brian T. Layden , Mudassir Rashid , Lu Cheng , Ali Cinar , Barbara Di Eugenio

Low-dose chest computed tomography (LDCT) captures pulmonary and cardiac structures in a single scan, enabling joint assessment of lung and cardiovascular health. Existing approaches typically model these domains independently and do not…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yifei Zhang , Jiashuo Zhang , Mojtaba Safari , Xiaofeng Yang , Liang Zhao

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

In the wake of the recent resurgence of the Datalog language of databases, together with its extensions for ontological reasoning settings, this work aims to bridge the gap between the theoretical studies of DatalogMTL (Datalog extended…

Databases · Computer Science 2025-06-11 Luigi Bellomarini , Livia Blasi , Markus Nissl , Emanuel Sallinger

Recent advances in medical large language models have explored Test-Time Reinforcement Learning (TTRL) to enhance reasoning. However, standard TTRL often relies on majority voting (MV) as a heuristic supervision signal, which can be…

Machine Learning · Computer Science 2026-03-11 Kailong Fan , Anqi Pu , Yichen Wu , Wanhua Li , Yicong Li , Hanspeter Pfister , Huafeng Liu , Xiang Li , Quanzheng Li , Ning Guo

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Computation and Language · Computer Science 2025-04-08 Juncheng Wu , Wenlong Deng , Xingxuan Li , Sheng Liu , Taomian Mi , Yifan Peng , Ziyang Xu , Yi Liu , Hyunjin Cho , Chang-In Choi , Yihan Cao , Hui Ren , Xiang Li , Xiaoxiao Li , Yuyin Zhou

Continuous physiological monitoring is central to emergency care, yet deploying trustworthy AI is challenging. While LLMs can translate complex physiological signals into clinical narratives, it is unclear how agentic systems perform…

Machine Learning · Computer Science 2026-03-05 Davide Gabrielli , Paola Velardi , Stefano Faralli , Bardh Prenkaj

While Long Chain-of-Thought (CoT) reasoning significantly improves Large Language Models (LLMs) performance on complex reasoning tasks, the substantial computational and memory costs of generating long CoT sequences limit their efficiency…

Artificial Intelligence · Computer Science 2026-02-03 Liang Zhang , Yu Zhao , Longyue Wang , Tianqi Shi , Weihua Luo , Kaifu Zhang , Jinsong Su

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

Machine Learning · Computer Science 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee

We propose TRACIE, a novel temporal reasoning dataset that evaluates the degree to which systems understand implicit events -- events that are not mentioned explicitly in natural language text but can be inferred from it. This introduces a…

Computation and Language · Computer Science 2021-05-11 Ben Zhou , Kyle Richardson , Qiang Ning , Tushar Khot , Ashish Sabharwal , Dan Roth

Large Reasoning Models (LRMs) introduce new opportunities for safety monitoring through their Chain of Thought (CoT) reasoning. However, CoT is not always faithful to the model's final output, undermining its reliability as a monitoring…

Computation and Language · Computer Science 2026-05-19 Maciej Chrabąszcz , Aleksander Szymczyk , Marcin Sendera , Tomasz Trzciński , Sebastian Cygert

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved…

Artificial Intelligence · Computer Science 2026-02-04 Linjie Mu , Zhongzhen Huang , Yannian Gu , Shengqian Qin , Shaoting Zhang , Xiaofan Zhang

Predicting the near-term behavior of a reactive agent is crucial in many robotic scenarios, yet remains challenging when observations of that agent are sparse or intermittent. Vision-Language Models (VLMs) offer a promising avenue by…