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Background: We present a Patient Simulator that leverages real world patient encounters which cover a broad range of conditions and symptoms to provide synthetic test subjects for development and testing of healthcare agentic models. The…

Computation and Language · Computer Science 2025-06-05 Sina Rashidian , Nan Li , Jonathan Amar , Jong Ha Lee , Sam Pugh , Eric Yang , Geoff Masterson , Myoung Cha , Yugang Jia , Akhil Vaid

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Artificial Intelligence · Computer Science 2025-04-11 Antoine Lizée , Pierre-Auguste Beaucoté , James Whitbeck , Marion Doumeingts , Anaël Beaugnon , Isabelle Feldhaus

AI based mental health diagnosis is often judged by benchmark accuracy, yet in practice its value depends on how psychologists respond whether they accept, adjust, or reject AI suggestions. Mental health makes this especially challenging:…

Human-Computer Interaction · Computer Science 2025-12-11 Filippo Cenacchi , Longbing Cao , Deborah Richards

There are growing concerns about the risks posed by AI companion applications designed for emotional engagement. Existing safety evaluations often rely on self-reported user data or interviews, offering limited insights into real-time…

Computation and Language · Computer Science 2026-05-04 Prerna Juneja , Lika Lomidze

As AI systems become increasingly integrated into daily life, their potential to exacerbate or trigger severe psychological harms remains poorly understood and inadequately tested. This paper presents a proactive methodology for…

Human-Computer Interaction · Computer Science 2025-11-13 Chayapatr Archiwaranguprok , Constanze Albrecht , Pattie Maes , Karrie Karahalios , Pat Pataranutaporn

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Patient safety training is essential for preparing healthcare professionals to identify, investigate, and prevent adverse events. However, conventional simulation-based approaches often require substantial faculty time, physical resources,…

Human-Computer Interaction · Computer Science 2026-03-20 Yuqi Hu , Qiwen Xiong , Zhenzhen Qin , Brandon Watanabe , Yujing Wang , Mirjana Prpa , Ilmi Yoon

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

The proliferation of Large Language Models (LLMs) and Intelligent Virtual Agents acting as psychotherapists presents significant opportunities for expanding mental healthcare access. However, their deployment has also been linked to serious…

Computation and Language · Computer Science 2025-09-23 Ian Steenstra , Timothy W. Bickmore

Training dialog policies for speech-based virtual assistants requires a plethora of conversational data. The data collection phase is often expensive and time consuming due to human involvement. To address this issue, a common solution is…

Computation and Language · Computer Science 2019-11-11 Maryam Fazel-Zarandi , Longshaokan Wang , Aditya Tiwari , Spyros Matsoukas

Large language models (LLMs) are increasingly used for mental health support, yet existing safety evaluations rely primarily on small, simulation-based test sets that have an unknown relationship to the linguistic distribution of real…

Computers and Society · Computer Science 2026-01-27 Caitlin A. Stamatis , Jonah Meyerhoff , Richard Zhang , Olivier Tieleman , Matteo Malgaroli , Thomas D. Hull

Healthcare professionals need effective ways to use, understand, and validate AI-driven clinical decision support systems. Existing systems face two key limitations: complex visualizations and a lack of grounding in scientific evidence. We…

Human-Computer Interaction · Computer Science 2025-07-08 Reza Samimi , Aditya Bhattacharya , Lucija Gosak , Gregor Stiglic , Katrien Verbert

Patient simulators are gaining traction in mental health training by providing scalable exposure to complex and sensitive patient interactions. Simulating depressed patients is particularly challenging, as safety constraints and high…

Computation and Language · Computer Science 2026-04-29 Nguyen Khoi Hoang , Shuhaib Mehri , Tse-An Hsu , Yi-Jyun Sun , Quynh Xuan Nguyen Truong , Khoa D Doan , Dilek Hakkani-Tür

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Problem: Effective patient-centered communication is a core competency for physicians. However, both seasoned providers and medical trainees report decreased confidence in leading conversations on sensitive topics such as goals of care or…

Human-Computer Interaction · Computer Science 2024-05-31 Simon N. Chu , Alex J. Goodell

In this study, we investigate the feasibility of using a human-centered artificial intelligence (AI) chat platform where medical specialists collaboratively assess complex cases. As the target population for this platform, we focus on…

Human-Computer Interaction · Computer Science 2025-03-24 Shinnosuke Sawano , Satoshi Kodera

This study investigates clinicians' perceptions and attitudes toward an assistive artificial intelligence (AI) system that employs a speech-based explainable ML algorithm for detecting depression. The AI system detects depression from…

Human-Computer Interaction · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

Healthcare conversational AI agents shouldn't be optimized only for clean benchmark accuracy in production-first regime; they must be optimized for the lived reality of patient conversations, where audio is imperfect, intent is indirect,…

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington
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