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We develop a statistical mechanical approach based on the replica method to study the design space of deep and wide neural networks constrained to meet a large number of training data. Specifically, we analyze the configuration space of the…

Disordered Systems and Neural Networks · Physics 2020-04-17 Hajime Yoshino

This report details an approach to improve the accuracy and precision of free energy difference estimates using thermodynamic integration data (slope of the free energy with respect to the switching variable lambda) and its application to…

Computational Physics · Physics 2010-01-19 Conrad Shyu , F. Marty Ytreberg

Local-to-global learning approach plays an essential role in Bayesian network (BN) structure learning. Existing local-to-global learning algorithms first construct the skeleton of a DAG (directed acyclic graph) by learning the MB (Markov…

Machine Learning · Computer Science 2021-12-21 Kui Yu , Zhaolong Ling , Lin Liu , Hao Wang , Jiuyong Li

Spectroscopy is a central pillar of materials characterization, providing useful information on properties like structure, composition, or excited state dynamics of a system. However, many spectroscopic techniques present challenges in…

Materials Science · Physics 2026-04-09 Amalya C. Johnson , Chris Fajardo , Leena Sansguiri , Weike Ye , Steven B. Torrisi

Density estimation is a fundamental problem in statistical learning. This problem is especially challenging for complex high-dimensional data due to the curse of dimensionality. A promising solution to this problem is given here in an…

Machine Learning · Statistics 2018-05-23 Saeed Saremi , Arash Mehrjou , Bernhard Schölkopf , Aapo Hyvärinen

We propose a new structured pruning framework for compressing Deep Neural Networks (DNNs) with skip connections, based on measuring the statistical dependency of hidden layers and predicted outputs. The dependence measure defined by the…

Machine Learning · Computer Science 2022-01-28 Mohammadreza Soltani , Suya Wu , Yuerong Li , Jie Ding , Vahid Tarokh

Machine learning techniques are being increasingly used as flexible non-linear fitting and prediction tools in the physical sciences. Fitting functions that exhibit multiple solutions as local minima can be analysed in terms of the…

We have developed a new simulation algorithm for free-energy calculations. The method is a multidimensional extension of the replica-exchange method. While pairs of replicas with different temperatures are exchanged during the simulation in…

Statistical Mechanics · Physics 2009-10-31 Yuji Sugita , Akio Kitao , Yuko Okamoto

We present a simple model system with four hard disks moving in a circular region for which free energy landscapes can be directly calculated and visualized in two and three dimensions. We construct several energy landscapes for our system…

Disordered Systems and Neural Networks · Physics 2021-04-06 Eric R. Weeks , Keely Criddle

Sampling the free energy surface, namely, the distribution of collective variables (CVs), is a crucial problem in statistical physics, as it underpins a better understanding of chemical reactions and conformational transitions. Traditional…

Machine Learning · Computer Science 2026-05-04 Zichen Liu , Tiejun Li

We propose a novel inverse-modelling approach which estimates the parameters of a simple land-surface model (LSM) by assimilating data into a differentiable physics-based forward model. The governing equations are expressed within a…

Atmospheric and Oceanic Physics · Physics 2026-04-17 Ruiyue Huang , Claire E. Heaney , Maarten van Reeuwijk

Physical systems ranging from elastic bodies to kinematic linkages are defined on high-dimensional configuration spaces, yet their typical low-energy configurations are concentrated on much lower-dimensional subspaces. This work addresses…

Score-based generative models (SGMs) learn a family of noise-conditional score functions corresponding to the data density perturbed with increasingly large amounts of noise. These perturbed data densities are linked together by the…

Machine Learning · Computer Science 2023-06-16 Chieh-Hsin Lai , Yuhta Takida , Naoki Murata , Toshimitsu Uesaka , Yuki Mitsufuji , Stefano Ermon

In this PhD thesis, we explore and apply methods inspired by the free energy principle to two important areas in machine learning and neuroscience. The free energy principle is a general mathematical theory of the necessary…

Artificial Intelligence · Computer Science 2021-08-31 Beren Millidge

We study reward-free reinforcement learning (RL) with linear function approximation, where the agent works in two phases: (1) in the exploration phase, the agent interacts with the environment but cannot access the reward; and (2) in the…

Machine Learning · Computer Science 2024-02-15 Junkai Zhang , Weitong Zhang , Quanquan Gu

Energy landscape analysis is a data-driven method to analyze multidimensional time series, including functional magnetic resonance imaging (fMRI) data. It has been shown to be a useful characterization of fMRI data in health and disease. It…

Neurons and Cognition · Quantitative Biology 2024-08-21 Pitambar Khanra , Johan Nakuci , Sarah Muldoon , Takamitsu Watanabe , Naoki Masuda

In many practical fluid dynamics experiments, measuring variables such as velocity and pressure is possible only at a limited number of sensor locations, \textcolor{black}{for a few two-dimensional planes, or for a small 3D domain in the…

Fluid Dynamics · Physics 2023-07-14 Ali Girayhan Özbay , Sylvain Laizet

The rising computational and energy demands of deep learning, particularly in large-scale architectures such as foundation models and large language models (LLMs), pose significant challenges to sustainability. Traditional gradient-based…

Machine Learning · Computer Science 2025-09-19 Mohammad Saleh Vahdatpour , Huaiyuan Chu , Yanqing Zhang

Model-free Reinforcement Learning (RL) algorithms such as Q-learning [Watkins, Dayan 92] have been widely used in practice and can achieve human level performance in applications such as video games [Mnih et al. 15]. Recently, equipped with…

Machine Learning · Computer Science 2019-05-03 Zhao Song , Wen Sun

This paper proposes distributed estimation procedures for three scalar-on-function regression models: the functional linear model (FLM), the functional non-parametric model (FNPM), and the functional partial linear model (FPLM). The…

Computation · Statistics 2026-01-08 Peilun He , Han Lin Shang , Nan Zou
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